6-Hydroxymellein is a
dihydroisocoumarin, a
phenolic
Phenolic is an adjective and a substantive (noun) that may apply to :
* Phenol (or carbolic acid), a colorless crystalline solid and aromatic compound
* Phenols, a class of chemical compounds that include phenol
* Phenolic content in wine
* Phenol ...
compound found in
carrots. It has also been isolated in ''
Aspergillus terreus
''Aspergillus terreus'', also known as ''Aspergillus terrestris'', is a fungus (mold) found worldwide in soil. Although thought to be strictly asexual until recently, ''A. terreus'' is now known to be capable of sexual reproduction. This saprotr ...
'' and shows an inhibition of
pollen development in ''
Arabidopsis thaliana''.
Biosynthesis
6-Methoxymellein is formed from
S-adenosyl methionine
''S''-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throug ...
and 6-hydroxymellein by the enzyme
6-hydroxymellein O-methyltransferase with secondary production of
S-adenosylhomocysteine.
6-Hydroxymellein biosynthesis pathway on www.biocyc.org
/ref>
References
Dihydroisocoumarins
Lactones
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