5-Fluoro-EPT (5F-EPT, 5-fluoro-''N''-ethyl-''N''-propyltryptamine) is a

psychedelic Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of ...

tryptamine derivative related to drugs such as EPT and 5-MeO-EPT. It acts as a potent full

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...

at the 5-HT_2A receptor with an EC₅₀ of 5.54 nM and an efficacy of 104% (compared to

serotonin Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vas ...

). It produces a head-twitch response in animal studies, and is claimed to have

antidepressant Antidepressants are a class of medication used to treat major depressive disorder, anxiety disorders, chronic pain conditions, and to help manage addictions. Common side-effects of antidepressants include dry mouth, weight gain, dizziness, hea ...

activity.

References

Psychedelic tryptamines Tryptamines Fluoroarenes {{nervous-system-drug-stub

See also

References