5-Fluoro-DET (5F-DET, 5-fluoro-''N,N''-diethyltryptamine) is a

tryptamine Tryptamine is an indolamine metabolite of the essential amino acid, tryptophan. The chemical structure is defined by an indole ─ a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the f ...

derivative related to drugs such as DET and

5-MeO-DET 5-MeO-DET or 5-methoxy-''N,N''-diethyltryptamine is a hallucinogenic tryptamine. Pharmacology 5-MeO-DET inhibits serotonin reuptake with an IC50 value of 2.4 μM and activates 5-HT2A receptors with an EC50 value of 8.11 nM. Effects Low dosages ...

. It acts as an inhibitor of the enzyme

myeloperoxidase Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the ''MPO'' gene on chromosome 17. MPO is most abundantly expressed in neutrophil granulocytes (a subtype of white blood cells), and produces hypohalous acids to carry ou ...

, and is also thought to be an

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...

at the 5-HT_2A receptor.

References

Psychedelic tryptamines Tryptamines Fluoroarenes {{nervous-system-drug-stub

See also

References