3-Methyl-PCPy (3-Me-PCPy) is an
arylcyclohexylamine derivative with an unusual spectrum of pharmacological effects, acting as both a potent
NMDA antagonist and also a
triple reuptake inhibitor
Triple is used in several contexts to mean "threefold" or a "treble":
Sports
* Triple (baseball), a three-base hit
* A basketball three-point field goal
* A figure skating jump with three rotations
* In bowling terms, three strikes in a row
* In ...
which inhibits reuptake of all three monoamine neurotransmitters
serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vas ...
,
dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic compound, organic chemical of the catecholamine and phenethylamine families. Dopamine const ...
and
noradrenaline. It also acts as a high
affinity
Affinity may refer to:
Commerce, finance and law
* Affinity (law), kinship by marriage
* Affinity analysis, a market research and business management technique
* Affinity Credit Union, a Saskatchewan-based credit union
* Affinity Equity Partn ...
sigma receptor ligand, selective for the
σ2 subtype. It produces both
stimulant
Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and inv ...
and
dissociative effects in animal behavioural studies.
Legal Status
3-Methyl-PCPy is covered by drug analogue laws in various jurisdictions (UK, Germany, Japan, Australia etc) as a generic arylcyclohexylamine derivative, and a
structural isomer
In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a chemical compound, compound is another compound whose molecule has the same number of atoms of each element, but with logically distinct chemical bond, b ...
of
phencyclidine.
See also
*
3-Methyl-PCP
*
BTCP
Benocyclidine, also known as benzothiophenylcyclohexylpiperidine (BTCP), is a psychoactive recreational drug of the arylcyclohexylamine class which is related to phencyclidine (PCP). It was first described in a patent application naming Marc C ...
*
Deoxymethoxetamine
Deoxymethoxetamine (3'-methyl-2-oxo-PCE, DMXE, 3D-MXE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It is an analogue of methoxetamine where the 3-methoxy group has been replaced by methyl. It has ...
*
Ephenidine
*
MDPCP
References
{{reflist
Arylcyclohexylamines
NMDA receptor antagonists
Serotonin–norepinephrine–dopamine reuptake inhibitors