Markéta Vondroušová was the defending champion, but chose not to participate.
Viktória Kužmová won the title after defeating
Verónica Cepede Royg 6–4, 1–6, 6–1 in the final.
Seeds
Draw
Finals
Top half
Bottom half
References
Main Draw
{{DEFAULTSORT:2018 Empire Slovak Open - Singles
Empire Slovak Open - Singles