2,3-Diaminopropionic acid (2,3-diaminopropionate, Dpr) is a

non-proteinogenic amino acid In biochemistry, non-coded or non-proteinogenic amino acids are distinct from the 22 proteinogenic amino acids (21 in eukaryotesplus formylmethionine in eukaryotes with prokaryote organelles like mitochondria) which are naturally encoded in the ge ...

found in certain secondary metabolites, including zwittermicin A and tuberactinomycin.

Biosynthesis

2,3-Diaminopropionate is formed by the

pyridoxal phosphate Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. The International Union of Biochemistry and Molecular Biology has catalogued more than 140 PLP-dependent ac ...

(PLP) mediated amination of

serine Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated − form under biological conditions), a carboxyl group (which is in the deprotonated − form un ...

References

{{DEFAULTSORT:Diaminopropionate, 2,3- Amino acids Carboxylic acids