Epiestriol () (brand names Actriol, Arcagynil, Klimadoral), or epioestriol (), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is a minor and weak
endogenous
Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.
In contrast, exogenous substances and processes are those that originate from outside of an organism.
For example, es ...
estrogen, and the 16β-
epimer of
estriol (which is 16α-hydroxy-17β-estradiol).
Epiestriol is (or has previously been) used clinically in the treatment of
acne.
In addition to its estrogenic actions, epiestriol has been found to possess significant
anti-inflammatory properties without
glycogenic activity or
immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like
hydrocortisone (a
glucocorticoid).
See also
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17α-Epiestriol
17α-Epiestriol, or simply 17-epiestriol, also known as 16α-hydroxy-17α-estradiol or estra-1,3,5(10)-triene-3,16α,17α-triol, is a minor and weak endogenous estrogen, and the 17α-epimer of estriol (which is 16α-hydroxy-17β-estradiol). It is ...
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16β,17α-Epiestriol
16β,17α-Epiestriol, or 16,17-epiestriol, also known as 16β-hydroxy-17α-estradiol, as well as estra-1,3,5(10)-triene-3,16β,17α-triol, is a minor and weak endogenous steroidal estrogen that is related to 17α-estradiol and estriol. Along wi ...
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Epimestrol
Epimestrol (, , ) (brand names Alene, Stimovul; former developmental code name ORG-817), also known as 3-methoxy-17-epiestriol, is a synthetic, steroidal estrogen and an estrogen ether and prodrug of 17-epiestriol. It has been used as a compo ...
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Mytatrienediol
References
Anti-acne preparations
Anti-inflammatory agents
Estranes
Estrogens
Hormones of the hypothalamus-pituitary-gonad axis
Sex hormones
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