α-cadinol
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α-Cadinol or 10α-hydroxy-4-cadinene is an
organic compound In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The ...
, a
sesquiterpenoid Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be cyclic or contain rings, including many unique combinations. Biochemical modificati ...
alcohol Alcohol most commonly refers to: * Alcohol (chemistry), an organic compound in which a hydroxyl group is bound to a carbon atom * Alcohol (drug), an intoxicant found in alcoholic drinks Alcohol may also refer to: Chemicals * Ethanol, one of sev ...
.


Natural occurrence

This compound is found in
essential oil An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the o ...
s and
extract An extract is a substance made by extracting a part of a raw material, often by using a solvent such as ethanol, oil or water. Extracts may be sold as tinctures, absolutes or in powder form. The aromatic principles of many spices, nuts, h ...
s of many plants, such as *'' Agrotaxis selaginoides'', * ''
Tabernaemontana catharinensis ''Tabernaemontana catharinensis'' is a species of plant in the family Apocynaceae.''Tabernaemontana c ...
'' * '' Litsea acutivena'' (7.7%), * '' Salvia aratocensis'' (20%), * '' Protium giganteum'' (7%), * '' Uvaria ovata'' root bark (13–24%), * '' Plinia trunciflora'' (19%) * '' Tanacetum sonbolii'' (35%) * ''
Schisandra chinensis ''Schisandra chinensis'' (common name: magnolia-vine, Chinese magnolia-vine, schisandra), whose fruit is called magnolia berry or five-flavor-fruit (from Chinese 五味子 ''wǔwèizi''), is a vine plant native to forests of Northern China, the ...
'' berries (5%), * ''
Melia azedarach ''Melia azedarach'', commonly known as the chinaberry tree, pride of India, bead-tree, Cape lilac, syringa berrytree, Persian lilac, Indian lilac, or white cedar, is a species of deciduous tree in the mahogany family, Meliaceae, that is native ...
'' (11%), * ''
Neolitsea parvigemma ''Neolitsea parvigemma'' is a species of small to medium-sized tree in the family Lauraceae. It is Endemism, endemic to Taiwan, and confined to the south central mountain regions of the island. A number of chemicals from ''N. parvigemma'' show i ...
'' (10%), * ''
Tetradenia riparia ''Tetradenia riparia'' is a species of flowering plant native to southern Africa. It belongs in the mint and sage family Lamiaceae. It is occasionally referred to as misty plume bush and is commonly used as a decorative garden plant due to its fl ...
'' (8%)


Biological activity

α-Cadinol was said to act as anti-fungal and as
hepatoprotective Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity. Hepatoprotective molecules used in emergency medicine * Acetylcysteine is considered the hepatopro ...
, and was proposed as a possible remedy for
drug-resistant Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. The term is used in the context of resistance that pathogens or cancers have "acquired", that is, ...
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
.


See also

*
δ-Cadinol δ-Cadinol is an organic compound, a sesquiterpenoid alcohol produced by many plants as well as some animals and microorganisms. It is a white crystalline solid, soluble in isopropyl ether and ethanol. It is an epimer of α-cadinol. δ-Cadinol ...
(torreyol)


References

{{DEFAULTSORT:Cadinol, alpha- Sesquiterpenes Tertiary alcohols Alkene derivatives Isopropyl compounds