Łucja Frey
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Łucja Frey
Łucja Frey or Łucja Frey-Gottesman (November 3, 1889 in Lwów – 1942?) was a Polish physician and neurologist, known for describing the syndrome later named after her. She was one of the first female academic neurologists in Europe. Frey perished during the Holocaust in 1942 in Lwów ghetto aged 53. Life Łucja Frey was born on November 3, 1889 in Lwów, then part of the Austro-Hungarian empire, as the daughter of the building contractor Szymon Symcha Frey and his wife, Dina (née Weinreb)Mirjam Moltrecht: Dr. med. Lucja Frey. Eine Ärztin aus Lwow 1889-1942. Rekonstruktion eines Lebens. Hartung Gorre Verlag Konstanz, 2004PDF/ref> Frey and her family were Jewish. She attended a Christian elementary school between 1896 and 1900. She graduated from Franciszek-Józef secondary school as an extern pupil in 1907. After graduation she studied mathematics and philosophy under professor Marian Smoluchowski (1872-1917). She was a student of the faculty of philosophy from 1907 to 1912, ...
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Retrosplenial Region
The retrosplenial cortex (RSC) is a cortical area in the brain comprising Brodmann areas 29 and 30. It is secondary association cortex, making connections with numerous other brain regions. The region's name refers to its anatomical location immediately behind the splenium of the corpus callosum in primates, although in rodents it is located more towards the brain surface and is relatively larger. Its function is currently not well understood, but its location close to visual areas and also to the hippocampal spatial/memory system suggest it may have a role in mediating between perceptual and memory functions, particularly in the spatial domain. However, its exact contribution to either space or memory processing has been hard to pin down. Anatomy There is large variation in the region's size across different species. In humans it comprises roughly 0.3% of the entire cortical surface whereas in rabbits it is at least 10% and in rats it extends for more than half the cerebrum dor ...
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Frontal Lobe
The frontal lobe is the largest of the four major lobes of the brain in mammals, and is located at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is parted from the parietal lobe by a groove between tissues called the central sulcus and from the temporal lobe by a deeper groove called the lateral sulcus (Sylvian fissure). The most anterior rounded part of the frontal lobe (though not well-defined) is known as the frontal pole, one of the three poles of the cerebrum. The frontal lobe is covered by the frontal cortex. The frontal cortex includes the premotor cortex, and the primary motor cortex – parts of the motor cortex. The front part of the frontal cortex is covered by the prefrontal cortex. There are four principal gyri in the frontal lobe. The precentral gyrus is directly anterior to the central sulcus, running parallel to it and contains the primary motor cortex, which controls voluntary movements of specific body parts ...
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Clivus (anatomy)
The clivus (, Latin for "slope"), or Blumenbach clivus, is a bony part of the cranium The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, the ... at the base of the skull. It is a shallow depression behind the dorsum sellae of the sphenoid bone. It slopes gradually to the anterior part of the basilar occipital bone at its junction with the sphenoid bone. It extends to the foramen magnum. It is related to the pons and the abducens nerve (CN VI). Structure The clivus is a shallow depression behind the dorsum sellae of the sphenoid bone. It slopes gradually to the anterior part of the basilar occipital bone at its junction with the sphenoid bone. Synchondrosis of these two bones forms the clivus. The clivus extends inferiorly to the foramen magnum. On axial planes, it sits just posterior to ...
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Charcot Joints
Neuropathic arthropathy (or neuropathic osteoarthropathy), also known as Charcot joint (often Charcot foot) after the first to describe it, Jean-Martin Charcot, refers to progressive degeneration of a weight-bearing joint, a process marked by bony destruction, bone resorption, and eventual deformity due to loss of sensation. Onset is usually insidious. If this pathological process continues unchecked, it can result in joint deformity, ulceration and/or superinfection, loss of function, and in the worst-case scenario, amputation or death. Early identification of joint changes is the best way to limit morbidity. Symptoms and signs The clinical presentation varies depending on the stage of the disease from mild swelling to severe swelling and moderate deformity. Inflammation, erythema, pain and increased skin temperature (3–7 degrees Celsius) around the joint may be noticeable on examination. X-rays may reveal bone resorption and degenerative changes in the joint. These findi ...
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Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the progressive loss of motor neurons that control voluntary muscles. ALS is the most common type of motor neuron diseases. Early symptoms of ALS include stiff muscles, muscle twitches, and gradual increasing weakness and muscle wasting. ''Limb-onset ALS'' begins with weakness in the arms or legs, while ''bulbar-onset ALS'' begins with difficulty speaking or swallowing. Half of the people with ALS develop at least mild difficulties with thinking and behavior, and about 15% develop frontotemporal dementia. Most people experience pain. The affected muscles are responsible for chewing food, speaking, and walking. Motor neuron loss continues until the ability to eat, speak, move, and finally the ability to breathe is lost. ALS eventually causes paralysis and early death, usually from respiratory failure. Most cases of ALS (a ...
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Brain Stem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating cardiac, and respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the body back to the ...
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Frederick Parkes Weber
Frederick Parkes Weber (8 May 1863 – 2 June 1962) was an English dermatologist and author who practiced medicine in London. Background Weber's father, Sir Hermann David Weber (1823–1918), was a personal physician to Queen Victoria. Weber was educated at Charterhouse and Trinity College, Cambridge. He subsequently studied medicine at St. Bartholomew's Hospital, and abroad at Vienna and Paris. Career Returning to England, he worked (since 1894) at the German Hospital, Dalston (London), later he became House Physician and House Surgeon at St. Bartholomew's Hospital. He was subsequently House Physician at Brompton Hospital and Physician at Mount Vernon Hospital. Weber contributed over 1200 medical articles and wrote 23 books over a period of 50 years. In 1922, he, along with his wife, published a philosophical medical tome called ''Aspects of Death and Correlated Aspects of Life in Art, Epigram, and Poetry''. Weber was a prodigious describer of new and unique dermat ...
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Friedrich Gustav Jakob Henle
Friedrich Gustav Jakob Henle (; 9 July 1809 – 13 May 1885) was a German physician, pathologist, and anatomist. He is credited with the discovery of the loop of Henle in the kidney. His essay, "On Miasma and Contagia," was an early argument for the germ theory of disease. He was an important figure in the development of modern medicine. Biography Henle was born in Fürth, Bavaria, to Simon and Rachel Diesbach Henle (Hähnlein). He was Jewish. After studying medicine at Heidelberg and at Bonn, where he took his doctor's degree in 1832, he became prosector in anatomy to Johannes Müller at Berlin. During the six years he spent in that position he published a large amount of work, including three anatomical monographs on new species of animals and papers on the structure of the lymphatic system, the distribution of epithelium in the human body, the structure and development of the hair, and the formation of mucus and pus. In 1840, he accepted the chair of anatomy at Zürich an ...
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Jules Baillarger
Jules Baillarger, full name Jules Gabriel François Baillarger (25 March 1809 – 31 December 1890), was a French neurologist and psychiatrist. Biography Baillarger was born in Montbazon, France. He studied medicine at the University of Paris under Jean-Étienne Dominique Esquirol (1772–1840), and while a student worked as an intern at the Charenton (asylum), Charenton mental institution. In 1840 he accepted a position at the Salpêtrière, and soon after became director of a ''maison de santé'' in Ivry-sur-Seine. Among his assistants at Ivry was Louis-Victor Marcé (1828-1864). With Jacques-Joseph Moreau (1804–1884) and others, he founded the influential ''Annales médico-psychologiques'' (Medical-Psychological Annals). Contributions and theories In 1840 Baillarger was the first physician to discover that the cerebral cortex was divided into six layers of alternate white and grey laminae. His name is associated with the inner and outer Band of Baillarger, bands of Baillar ...
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Charles-Édouard Brown-Séquard
Charles-Édouard Brown-Séquard FRS (8 April 1817 – 2 April 1894) was a Mauritian physiologist and neurologist who, in 1850, became the first to describe what is now called Brown-Séquard syndrome. Early life Brown-Séquard was born at Port Louis, Mauritius, to an American father and a French mother. He attended the Royal College in Mauritius, and graduated in medicine at Paris in 1846. He then returned to Mauritius with the intention of practising there, but in 1852 he went to the United States. There he was appointed to the faculty of the Medical College of Virginia where he conducted experiments in the basement of the Egyptian Building. He was elected as a member of the American Philosophical Society in 1854. Later life He returned to Paris, and in 1859 he migrated to London, becoming physician to the National Hospital for the Paralysed and Epileptic. There he stayed for about five years, expounding his views on the pathology of the nervous system in numerous lectures wh ...
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