Vertical Occipital Fasciculus
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Vertical Occipital Fasciculus
The vertical occipital fasciculus is a fascicle of white matter running vertically in the rear of the brain. It is found at least in primates. It "is the only major fiber bundle connecting dorsolateral and ventrolateral visual cortex." Early discovery Originally depicted by Carl Wernicke, who called it the ''senkrechte Occipitalbündel'' (vertical occipital bundle), the region was practically lost to scientific knowledge during the twentieth century. Theodor Meynert had described the brain's other white matter tracts as being horizontally oriented, and did not accept Wernicke's finding. Heinrich Obersteiner named the area the "fasciculus occipitalis perpendicularis", and Heinrich Sachs named the area the "stratum profundum convexitatis". It appeared in a 1918 edition of Gray's Anatomy, but fell into obscurity. A diffusion tensor imaging (DTI) study in 2004 noted an area of short-range association fibers in the lateral occipital lobe The occipital lobe is one of the four ...
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White Matter
White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. White matter is named for its relatively light appearance resulting from the lipid content of myelin. However, the tissue of the freshly cut brain appears pinkish-white to the naked eye because myelin is composed largely of lipid tissue veined with capillaries. Its white color in prepared specimens is due to its usual preservation in formaldehyde. Structure White matter White matter is composed of bundles, which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, which allows electrical signals to jump, rather than c ...
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Visual Cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each hemisphere's V1 ...
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Carl Wernicke
Carl (or Karl) Wernicke (; ; 15 May 1848 – 15 June 1905) was a German physician, anatomist, psychiatrist and neuropathologist. He is known for his influential research into the pathological effects of specific forms of encephalopathy and also the study of receptive aphasia, both of which are commonly associated with Wernicke's name and referred to as Wernicke encephalopathy and Wernicke's aphasia, respectively. His research, along with that of Paul Broca, led to groundbreaking realizations of the localization of brain function, specifically in speech. As such, Wernicke's area (a.k.a. Wernicke's Speech Area) has been named after the scientist. Biography Wernicke was born on May 15, 1848, in Tarnowitz, a small town in Upper Silesia, Prussia, now Tarnowskie Góry, Poland. He obtained his secondary education at the gymnasium in Oppeln, which is a school near the university of Breslau. Wernicke then studied medicine at the University of Breslau and did graduate work studying langu ...
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Theodor Meynert
Theodor Hermann Meynert (15 June 1833 – 31 May 1892) was a German-Austrian psychiatrist, neuropathologist and anatomist born in Dresden. Meynert believed that disturbances in brain development could be a predisposition for psychiatric illness and that certain psychoses are reversible. In 1861 he earned his medical doctorate, and in 1875 became director of the psychiatric clinic associated with the University of Vienna. Some of his better known students in Vienna were Josef Breuer, Sigmund Freud, who in 1883 worked at Meynert's psychiatric clinic, and Julius Wagner-Jauregg, who introduced fever treatment for syphilis. Meynert later distanced himself from Freud because of the latter's involvement with practices such as hypnosis. Meynert also ridiculed Freud's idea of male hysteria; though some authors believe this to be due to his own hidden suffering of the illness, prompting a reconciliation with Freud near to his death. Other famous students of Meynert's were Russian neuropsychi ...
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Heinrich Obersteiner
Heinrich Obersteiner (13 November 1847 – 19 November 1922) was an Austrian neurologist born in Vienna. In 1870 earned his doctorate from the University of Vienna, where he worked in the laboratory of Ernst Wilhelm von Brücke (1819–1892). In 1873 he earned his habilitation for pathology and anatomy of the nervous system at the University of Vienna, becoming an associate professor in 1880, and receiving the title of "full professor" in 1898. He was also director of a private mental institution at Oberdöbling, outside of Vienna. In 1882 he established an internationally known neurological institute in Vienna. The eponymous Obersteiner–Redlich line is named after him, along with Emil Redlich (1866–1930). This zone is where the central nervous system and peripheral nervous system meet, as well as the place where Schwann cells meet oligodendroglia cells. Written works * '' Anleitung beim Studium des baues der nervösen Centralorgane im gesunden und kranken Zustande''. L ...
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Heinrich Sachs
Heinrich Sachs (1863 - 1928) was a late 19th and early 20th century German neurologist and neuroanatomist best known for his atlas of the brain's white matter White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution .... Scientific career Heinrich Sachs was born in Halberstadt, Germany, in 1863. He studied medicine in Berlin, graduating in 1885 with a dissertation on amyotrophic lateral sclerosis. After practicing as a physician for a few years, he joined neuropathologist Carl Wernicke's laboratory at University Hospital, Breslau, where he studied spatial perception and gained a postdoctoral qualification (habilitation) in psychiatry and neurology in 1897. In 1892, Sachs published the first installment of an ambitious and informative atlas of the brain's white matter, with a focus on the ana ...
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Gray's Anatomy
''Gray's Anatomy'' is a reference book of human anatomy written by Henry Gray, illustrated by Henry Vandyke Carter, and first published in London in 1858. It has gone through multiple revised editions and the current edition, the 42nd (October 2020), remains a standard reference, often considered "the doctors' bible". Earlier editions were called ''Anatomy: Descriptive and Surgical'', ''Anatomy of the Human Body'' and ''Gray's Anatomy: Descriptive and Applied'', but the book's name is commonly shortened to, and later editions are titled, ''Gray's Anatomy''. The book is widely regarded as an extremely influential work on the subject. Publication history Origins The English anatomist Henry Gray was born in 1827. He studied the development of the endocrine glands and spleen and in 1853 was appointed Lecturer on Anatomy at St George's Hospital Medical School in London. In 1855, he approached his colleague Henry Vandyke Carter with his idea to produce an inexpensive and ac ...
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TheGuardian
''The Guardian'' is a British daily newspaper. It was founded in 1821 as ''The Manchester Guardian'', and changed its name in 1959. Along with its sister papers ''The Observer'' and ''The Guardian Weekly'', ''The Guardian'' is part of the Guardian Media Group, owned by the Scott Trust Limited, Scott Trust. The trust was created in 1936 to "secure the financial and editorial independence of ''The Guardian'' in perpetuity and to safeguard the journalistic freedom and liberal values of ''The Guardian'' free from commercial or political interference". The trust was converted into a limited company in 2008, with a constitution written so as to maintain for ''The Guardian'' the same protections as were built into the structure of the Scott Trust by its creators. Profits are reinvested in journalism rather than distributed to owners or shareholders. It is considered a newspaper of record in the UK. The editor-in-chief Katharine Viner succeeded Alan Rusbridger in 2015. Since 2018, th ...
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Diffusion Tensor Imaging
Diffusion-weighted magnetic resonance imaging (DWI or DW-MRI) is the use of specific MRI sequences as well as software that generates images from the resulting data that uses the diffusion of water molecules to generate contrast in MR images. It allows the mapping of the diffusion process of molecules, mainly water, in biological tissues, in vivo and non-invasively. Molecular diffusion in tissues is not random, but reflects interactions with many obstacles, such as macromolecules, fibers, and membranes. Water molecule diffusion patterns can therefore reveal microscopic details about tissue architecture, either normal or in a diseased state. A special kind of DWI, diffusion tensor imaging (DTI), has been used extensively to map white matter tractography in the brain. Introduction In diffusion weighted imaging (DWI), the intensity of each image element (voxel) reflects the best estimate of the rate of water diffusion at that location. Because the mobility of water is driven by t ...
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Occipital Lobe
The occipital lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The name derives from its position at the back of the head, from the Latin ''ob'', "behind", and ''caput'', "head". The occipital lobe is the visual processing center of the mammalian brain containing most of the anatomical region of the visual cortex. The primary visual cortex is Brodmann area 17, commonly called V1 (visual one). Human V1 is located on the medial side of the occipital lobe within the calcarine sulcus; the full extent of V1 often continues onto the occipital pole. V1 is often also called striate cortex because it can be identified by a large stripe of myelin, the Stria of Gennari. Visually driven regions outside V1 are called extrastriate cortex. There are many extrastriate regions, and these are specialized for different visual tasks, such as visuospatial processing, color differentiation, and motion perception. Bilateral lesions of the occipital lobe can lead ...
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