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Thomson (unit)
The thomson (symbol: Th) is a unit that has appeared infrequently in scientific literature relating to the field of mass spectrometry as a unit of mass-to-charge ratio. The unit was proposed by Cooks and Rockwood naming it in honour of J. J. Thomson who measured the mass-to-charge ratio of electrons and ions. Definition The thomson is defined as : 1~\mathrm = 1~\frac \approx 1.036426 \times 10^\,\mathrm where Da is the symbol for the unit dalton (also called the unified atomic mass unit, symbol u), and ''e'' is the elementary charge which is the unit of electric charge in the system of Hartree atomic units. For example, the ion C7H72+ has a mass of 91 Da. Its charge number is +2, and hence its charge is 2''e''. The ion will be observed at 45.5 Th in a mass spectrum. The thomson allows for negative values for negatively charged ions. For example, the benzoate anion would be observed at −121 Th since the charge is −''e''. Use The thomson has been used by some m ...
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Mass-to-charge Ratio
The mass-to-charge ratio (''m''/''Q'') is a physical quantity relating the ''mass'' (quantity of matter) and the ''electric charge'' of a given particle, expressed in units of kilograms per coulomb (kg/C). It is most widely used in the electrodynamics of charged particles, e.g. in electron optics and ion optics. It appears in the scientific fields of electron microscopy, cathode ray tubes, accelerator physics, nuclear physics, Auger electron spectroscopy, cosmology and mass spectrometry. The importance of the mass-to-charge ratio, according to classical electrodynamics, is that two particles with the same mass-to-charge ratio move in the same path in a vacuum, when subjected to the same electric and magnetic fields. On rare occasions, the thomson has been used as its unit in the field of mass spectrometry. Some disciplines use the charge-to-mass ratio (''Q''/''m'') instead, which is the multiplicative inverse of the mass-to-charge ratio. The CODATA recommended value for an ...
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Mass Spectrometry
Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures. A mass spectrum is a type of plot of the ion signal as a function of the mass-to-charge ratio. These spectra are used to determine the elemental or isotopic signature of a sample, the masses of particles and of molecules, and to elucidate the chemical identity or structure of molecules and other chemical compounds. In a typical MS procedure, a sample, which may be solid, liquid, or gaseous, is ionized, for example by bombarding it with a beam of electrons. This may cause some of the sample's molecules to break up into positively charged fragments or simply become positively charged without fragmenting. These ions (fragments) are then separated accordin ...
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Mass-to-charge Ratio
The mass-to-charge ratio (''m''/''Q'') is a physical quantity relating the ''mass'' (quantity of matter) and the ''electric charge'' of a given particle, expressed in units of kilograms per coulomb (kg/C). It is most widely used in the electrodynamics of charged particles, e.g. in electron optics and ion optics. It appears in the scientific fields of electron microscopy, cathode ray tubes, accelerator physics, nuclear physics, Auger electron spectroscopy, cosmology and mass spectrometry. The importance of the mass-to-charge ratio, according to classical electrodynamics, is that two particles with the same mass-to-charge ratio move in the same path in a vacuum, when subjected to the same electric and magnetic fields. On rare occasions, the thomson has been used as its unit in the field of mass spectrometry. Some disciplines use the charge-to-mass ratio (''Q''/''m'') instead, which is the multiplicative inverse of the mass-to-charge ratio. The CODATA recommended value for an ...
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Rapid Communications In Mass Spectrometry
''Rapid Communications in Mass Spectrometry'' (''RCM'') is a biweekly peer-reviewed scientific journal published since 1987 by John Wiley & Sons. It covers research on all aspects of mass spectrometry. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 2.419. RCM Beynon Prize To mark the 80th birthday of John H. Beynon John H. Beynon FRS (29 December 1923 – 24 August 2015) was a Welsh chemist and physicist known for his work in mass spectrometry. Education and military service Beynon was born in the Welsh coal-mining town of Ystalyfera and was the older o ..., the founding Editor of RCM, in 2004 an annual award was established in his honour by the publishers. The award is made on the recommendation of an ad hoc Sub-committee of the Editorial Board of RCM. References External links * Mass spectrometry journals Publications established in 1987 Wiley (publisher) academic journals {{biochem-journal-stub ...
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Dalton (unit)
The dalton or unified atomic mass unit (symbols: Da or u) is a non-SI unit of mass widely used in physics and chemistry. It is defined as of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest. The atomic mass constant, denoted ''m''u, is defined identically, giving . This unit is commonly used in physics and chemistry to express the mass of atomic-scale objects, such as atoms, molecules, and elementary particles, both for discrete instances and multiple types of ensemble averages. For example, an atom of helium-4 has a mass of . This is an intrinsic property of the isotope and all helium-4 atoms have the same mass. Acetylsalicylic acid (aspirin), , has an average mass of approximately . However, there are no acetylsalicylic acid molecules with this mass. The two most common masses of individual acetylsalicylic acid molecules are , having the most common isotopes, and , in which one carbon is carbon-13. The molecular mass ...
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Unified Atomic Mass Unit
The dalton or unified atomic mass unit (symbols: Da or u) is a non-SI unit of mass widely used in physics and chemistry. It is defined as of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest. The atomic mass constant, denoted ''m''u, is defined identically, giving . This unit is commonly used in physics and chemistry to express the mass of atomic-scale objects, such as atoms, molecules, and elementary particles, both for discrete instances and multiple types of ensemble averages. For example, an atom of helium-4 has a mass of . This is an intrinsic property of the isotope and all helium-4 atoms have the same mass. Acetylsalicylic acid (aspirin), , has an average mass of approximately . However, there are no acetylsalicylic acid molecules with this mass. The two most common masses of individual acetylsalicylic acid molecules are , having the most common isotopes, and , in which one carbon is carbon-13. The molecular mass ...
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Elementary Charge
The elementary charge, usually denoted by is the electric charge carried by a single proton or, equivalently, the magnitude of the negative electric charge carried by a single electron, which has charge −1 . This elementary charge is a fundamental physical constant. In the SI system of units, the value of the elementary charge is exactly defined as e =  coulombs, or 160.2176634 zeptocoulombs (zC). Since the 2019 redefinition of SI base units, the seven SI base units are defined by seven fundamental physical constants, of which the elementary charge is one. In the centimetre–gram–second system of units (CGS), the corresponding quantity is . Robert A. Millikan and Harvey Fletcher's oil drop experiment first directly measured the magnitude of the elementary charge in 1909, differing from the modern accepted value by just 0.6%. Under assumptions of the then-disputed atomic theory, the elementary charge had also been indirectly inferred to ~3% accuracy from bla ...
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Units Of Measurement
A unit of measurement is a definite magnitude (mathematics), magnitude of a quantity, defined and adopted by convention or by law, that is used as a standard for measurement of the same kind of quantity. Any other quantity of that kind can be expressed as a multiple of the unit of measurement. For example, a length is a physical quantity. The metre (symbol m) is a unit of length that represents a definite predetermined length. For instance, when referencing "10 metres" (or 10 m), what is actually meant is 10 times the definite predetermined length called "metre". The definition, agreement, and practical use of units of measurement have played a crucial role in human endeavour from early ages up to the present. A multitude of System of measurement, systems of units used to be very common. Now there is a global standard, the International System of Units (SI), the modern form of the metric system. In trade, weights and measures is often a subject of governmental r ...
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Electric Charge
Electric charge is the physical property of matter that causes charged matter to experience a force when placed in an electromagnetic field. Electric charge can be ''positive'' or ''negative'' (commonly carried by protons and electrons respectively). Like charges repel each other and unlike charges attract each other. An object with an absence of net charge is referred to as neutral. Early knowledge of how charged substances interact is now called classical electrodynamics, and is still accurate for problems that do not require consideration of quantum effects. Electric charge is a conserved property; the net charge of an isolated system, the amount of positive charge minus the amount of negative charge, cannot change. Electric charge is carried by subatomic particles. In ordinary matter, negative charge is carried by electrons, and positive charge is carried by the protons in the nuclei of atoms. If there are more electrons than protons in a piece of matter, it will have ...
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Hartree Atomic Units
The Hartree atomic units are a system of natural units of measurement which is especially convenient for atomic physics and computational chemistry calculations. They are named after the physicist Douglas Hartree. By definition, the following four fundamental physical constants may each be expressed as the numeric value 1 multiplied by a coherent unit of this system: * Reduced Planck constant: \hbar, also known as the atomic unit of action * Elementary charge: e, also known as the atomic unit of charge * Bohr radius: a_0, also known as the atomic unit of length * Electron mass: m_\text, also known as the atomic unit of mass Atomic units are often abbreviated "a.u." or "au", not to be confused with the same abbreviation used also for astronomical units, arbitrary units, and absorbance units in other contexts. Defining constants Each unit in this system can be expressed as a product of powers of four physical constants without a multiplying constant. This makes it a coherent sys ...
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Benzoate
Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, which was for a long time its only source. Benzoic acid occurs naturally in many plants and serves as an intermediate in the biosynthesis of many secondary metabolites. Salts of benzoic acid are used as food preservatives. Benzoic acid is an important precursor for the industrial synthesis of many other organic substances. The salts and esters of benzoic acid are known as benzoates . History Benzoic acid was discovered in the sixteenth century. The dry distillation of gum benzoin was first described by Nostradamus (1556), and then by Alexius Pedemontanus (1560) and Blaise de Vigenère (1596). Justus von Liebig and Friedrich Wöhler determined the composition of benzoic acid. These latter also investigated how hippuric acid is related ...
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Alexander Alexeyevich Makarov
Alexander Alexeyevich Makarov, (born 1966) is a Russian physicist who led the team that developed the Orbitrap, a type of mass spectrometer, and received the 2008 American Society for Mass Spectrometry Distinguished Contribution in Mass Spectrometry Award for this development. In November 2013 he was appointed to Professor by Special Appointment of High Resolution Mass Spectrometry at the Department of Chemistry and the Bijvoet Center for Biomolecular Research of Utrecht University in the Netherlands. As of 2016, he is Director of Global Research for Life Sciences Mass Spectrometry at Thermo Fisher Scientific. Early life and education * 1989 Moscow Engineering Physics Institute - M.S. Molecular Physics * 1993 Moscow Engineering Physics Institute - Ph.D. Physics and Mathematics * 1994-1996 Warwick University - Postdoctoral Appointment Awards * 2008 ASMS Distinguished Contribution in Mass Spectrometry Award * 2012 Thomson Medal Award * 2020 Fellow of the Royal Society F ...
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