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Soman
Soman (or GD, EA 1210, Zoman, PFMP, A-255, systematic name: ''O''-pinacolyl methylphosphonofluoridate) is an extremely toxic chemical substance. It is a nerve agent, interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase. It is an inhibitor of both acetylcholinesterase and butyrylcholinesterase. As a chemical weapon, it is classified as a weapon of mass destruction by the United Nations according to UN Resolution 687. Its production is strictly controlled, and stockpiling is outlawed by the Chemical Weapons Convention of 1993 where it is classified as a Schedule 1 substance. Soman was the third of the so-called ''G-series'' nerve agents to be discovered along with GA (tabun), GB (sarin), and GF (cyclosarin). When pure, soman is a volatile, corrosive, and colorless liquid with a faint odor like that of mothballs or rotten fruit. More commonly, it is a yellow to brown color and has a strong odor described as similar to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nerve Agent
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are acetylcholinesterase inhibitors used as poison. Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles. Some nerve agents are readily vaporized or aerosolized, and the primary portal of entry into the body is the respiratory system. Nerve agents can also be absorbed through the skin, requiring that those likely to be subjected to such agents wear a full body suit in addition to a respirat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabun (nerve Agent)
Tabun or GA is an extremely toxic synthetic organophosphorus compound. It is a clear, colorless, and tasteless liquid with a faint fruity odor.Facts About Tabun National Terror Alert Response System It is classified as a because it fatally interferes with normal functioning of the mammalian nervous system. Its production is strictly controlled and stockpiling outlawed by the of 1993. Tabun is the first of the ''G-series'' nerve agents ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Weapon
A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans. According to the Organisation for the Prohibition of Chemical Weapons (OPCW), this can be any chemical compound intended as a weapon "or its precursor that can cause death, injury, temporary incapacitation or sensory irritation through its chemical action. Munitions or other delivery devices designed to deliver chemical weapons, whether filled or unfilled, are also considered weapons themselves." Chemical weapons are classified as weapons of mass destruction (WMD), though they are distinct from nuclear weapons, biological weapons, and radiological weapons. All may be used in warfare and are known by the military acronym NBC (for nuclear, biological, and chemical warfare). Weapons of mass destruction are distinct from conventional weapons, which are primarily effective due to their explosive, kinetic, or incendiary potential. Chemical weapons can be widely disp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabun (nerve Agent)
Tabun or GA is an extremely toxic synthetic organophosphorus compound. It is a clear, colorless, and tasteless liquid with a faint fruity odor.Facts About Tabun National Terror Alert Response System It is classified as a because it fatally interferes with normal functioning of the mammalian nervous system. Its production is strictly controlled and stockpiling outlawed by the of 1993. Tabun is the first of the ''G-series'' nerve agents ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Schedule 1 Substances (CWC)
Schedule 1 substances, in the sense of the Chemical Weapons Convention, are chemicals which can either be used as chemical weapons themselves or used in the manufacture of chemical weapons and which have no, or very limited, uses outside of chemical warfare. These may be produced or used for research, medical, pharmaceutical or chemical weapon defence testing (called "protective testing" in the treaty) purposes but production above 100 grams per year must be declared to the OPCW in accordance with Part VI of the "Verification Annex". A country is limited to possessing a maximum of one tonne of these materials. They are sub-divided into Part A substances, which are chemicals that can be used directly as weapons, and Part B which are precursors useful in the manufacture of chemical weapons. Examples are mustard and nerve agents, and substances which are solely used as precursor chemicals in their manufacture. A few of these chemicals have very small-scale non-military application ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Kuhn
Richard Johann Kuhn (; 3 December 1900 – 1 August 1967) was an Austrian-German biochemist who was awarded the Nobel Prize in Chemistry in 1938 "for his work on carotenoids and vitamins". Biography Early life Kuhn was born in Vienna, Austria, where he attended grammar school and high school. His interest in chemistry surfaced early; however he had many interests and decided late to study chemistry. Between 1910 and 1918 he was a schoolmate of Wolfgang Pauli, who was awarded the Nobel Prize in Physics for 1945. Beginning in 1918, Kuhn attended lectures at the University of Vienna in chemistry. He finished his chemistry studies at University of Munich and received his doctoral degree in 1922 with Richard Willstätter for a scientific work on enzymes. After graduating, Kuhn continued his scientific career, first in Munich, then at the ETH Zurich and from 1929 onwards at the University of Heidelberg, where he was head of the chemistry department beginning in 1937. In 1928 he m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gerhard Schrader
Gerhard Schrader (25 February 1903 – 10 April 1990) was a German chemist specializing in the discovery of new insecticides, hoping to make progress in the fight against hunger in the world. Schrader is best known for his accidental discovery of nerve agents such as sarin and tabun, and for this he is sometimes called the "father of the nerve agents". Schrader was born in Bortfeld, near Wendeburg, Germany. He attended gymnasium in Braunschweig and later studied chemistry at Braunschweig University of Technology. He was later employed at the Bayer AG division of IG Farben. Schrader discovered several very effective insecticides, including bladan (the first fully synthetic contact insecticide Hexaethyl tetraphosphate being a constituent), and parathion (E 605). In 1936, while employed by the large German conglomerate IG Farben, he was experimenting with a class of compounds called organophosphates, which killed insects by interrupting their nervous systems. Instead of a new ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pinacolyl Alcohol
Pinacolyl alcohol is a common name for 3,3-dimethylbutan-2-ol, also known as pine alcohol. It is one of the isomeric hexanols and a secondary alcohol. Pinacolyl alcohol appears on the List of Schedule 2 substances (CWC) as a precursor for the nerve agent soman. See also *Soman *Isopropyl alcohol Isopropyl alcohol (IUPAC name propan-2-ol and also called isopropanol or 2-propanol) is a colorless, flammable organic compound with a pungent alcoholic odor. As an isopropyl group linked to a hydroxyl group ( chemical formula ) it is the s ... References External links IPCS INTOX Databank Hexanols Nerve agent precursors Secondary alcohols {{Alcohol-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Konrad Henkel
Konrad Henkel (25 October 1915 - 24 April 1999) was a German chemist and industrialist, and long-time head of the Henkel Group. Life Konrad Henkel was born in 1915, the grandson of Fritz Henkel (1848-1930), founder of the detergent factory Henkel & Cie in Aachen in 1876 moved in 1878 to Düsseldorf. Henkel was the second son of Hugo Henkel and Gerda Henkel. He graduated from high school in Düsseldorf and then studied chemistry at the Technical University of Munich. He then transferred to the Technical University of Braunschweig and later to the Technical University of Karlsruhe, where he received his doctorate in 1939. Between 1939 and 1945, he worked at the then Kaiser Wilhelm Institute for Medical Research in Heidelberg, where he conducted research on poison gases under the supervision of Richard Kuhn (co-discoverer of Soman). In 1948, he joined Henkel as a chemist in product development. From 1949 to 1956, Konrad Henkel was Head of Product Development at Henkel and fin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetylcholinesterase
Acetylcholinesterase ( HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters: : acetylcholine + H2O = choline + acetate It is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides. Enzyme structure and mechanism AChE is a hydrolase that hydrolyzes choline esters. It has a very high catalytic activity—each molecule of AChE degrades about 25,000 molecules of acetylcholine (ACh) per second, approaching the limit allowed by diffusion of the substrate. The active site of AChE ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Weapon Proliferation
Many nations continue to research and/or stockpile chemical weapon agents despite numerous efforts to reduce or eliminate them. Most states have joined the Chemical Weapons Convention (CWC), which required the destruction of all chemical weapons by 2012. Twelve nations have declared chemical weapons production facilities and six nations have declared stockpiles of chemical weapons. All of the declared production facilities have been destroyed or converted to civilian use after the treaty went into force. CWC states with declared stockpiles Of 190 signatory nations to the CWC, state parties listed below have also declared stockpiles, agreed to monitored disposal, and verification, and in some cases, used chemical weapons in conflict. Both military targets and civilian populations have been affected; affected populations were not always damaged collaterally; instead, at times: themselves the target of the attack. , only North Korea and the United States are confirmed to have remain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weapon Of Mass Destruction
A weapon of mass destruction (WMD) is a chemical, biological, radiological, nuclear, or any other weapon that can kill and bring significant harm to numerous individuals or cause great damage to artificial structures (e.g., buildings), natural structures (e.g., mountains), or the biosphere. The scope and usage of the term has evolved and been disputed, often signifying more politically than technically. Originally coined in reference to aerial bombing with chemical explosives during World War II, it has later come to refer to large-scale weaponry of warfare-related technologies, such as chemical, biological, radiological, or nuclear warfare. Early uses of this term The first use of the term "weapon of mass destruction" on record is by Cosmo Gordon Lang, Archbishop of Canterbury, in 1937 in reference to the aerial bombing of Guernica, Spain: At the time, nuclear weapons had not been developed. Japan conducted research on biological weapons (see Unit 731), and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
