Small Angle X-ray Scattering
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Small Angle X-ray Scattering
Small-angle X-ray scattering (SAXS) is a small-angle scattering technique by which nanoscale density differences in a sample can be quantified. This means that it can determine nanoparticle size distributions, resolve the size and shape of (monodisperse) macromolecules, determine pore sizes, characteristic distances of partially ordered materials, and much more. This is achieved by analyzing the elastic scattering behaviour of X-rays when travelling through the material, recording their scattering at small angles (typically 0.1 – 10°, hence the "Small-angle" in its name). It belongs to the family of small-angle scattering (SAS) techniques along with small-angle neutron scattering, and is typically done using hard X-rays with a wavelength of 0.07 – 0.2 nm.. Depending on the angular range in which a clear scattering signal can be recorded, SAXS is capable of delivering structural information of dimensions between 1 and 100 nm, and of repeat distances in partially ordered sys ...
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Small-angle Scattering
Small-angle scattering (SAS) is a scattering technique based on deflection of collimated radiation away from the straight trajectory after it interacts with structures that are much larger than the wavelength of the radiation. The deflection is small (0.1-10°) hence the name ''small-angle''. SAS techniques can give information about the size, shape and orientation of structures in a sample. SAS is a powerful technique for investigating large-scale structures from 10 Å up to thousands and even several tens of thousands of angstroms. The most important feature of the SAS method is its potential for analyzing the inner structure of disordered systems, and frequently the application of this method is a unique way to obtain direct structural information on systems with random arrangement of density inhomogeneities in such large-scales. Currently, the SAS technique, with its well-developed experimental and theoretical procedures and wide range of studied objects, is a self-contained b ...
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Polymersome
In biotechnology, polymersomesDischer B M; Won Y Y; Ege D S; Lee J C; Bates F S; Discher D E; Hammer D A ''Science'' (1999), ''284''(5417), 1143-6. are a class of artificial vesicles, tiny hollow spheres that enclose a solution. Polymersomes are made using amphiphilic synthetic block copolymers to form the vesicle membrane, and have radii ranging from 50 nm to 5 µm or more. Most reported polymersomes contain an aqueous solution in their core and are useful for encapsulating and protecting sensitive molecules, such as drugs, enzymes, other proteins and peptides, and DNA and RNA fragments. The polymersome membrane provides a physical barrier that isolates the encapsulated material from external materials, such as those found in biological systems. Synthosomes are polymersomes engineered to contain channels (transmembrane proteins) that allow certain chemicals to pass through the membrane, into or out of the vesicle. This allows for the collection or enzymatic modification ...
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Collimated Beam
A collimated beam of light or other electromagnetic radiation has parallel rays, and therefore will spread minimally as it propagates. A perfectly collimated light beam, with no divergence, would not disperse with distance. However, diffraction prevents the creation of any such beam. Light can be approximately collimated by a number of processes, for instance by means of a collimator. Perfectly collimated light is sometimes said to be ''focused at infinity''. Thus, as the distance from a point source increases, the spherical wavefronts become flatter and closer to plane waves, which are perfectly collimated. Other forms of electromagnetic radiation can also be collimated. In radiology, X-rays are collimated to reduce the volume of the patient's tissue that is irradiated, and to remove stray photons that reduce the quality of the x-ray image ("film fog"). In scintigraphy, a gamma ray collimator is used in front of a detector to allow only photons perpendicular to the surface to be ...
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Synchrotron
A synchrotron is a particular type of cyclic particle accelerator, descended from the cyclotron, in which the accelerating particle beam travels around a fixed closed-loop path. The magnetic field which bends the particle beam into its closed path increases with time during the accelerating process, being ''synchronized'' to the increasing kinetic energy of the particles. The synchrotron is one of the first accelerator concepts to enable the construction of large-scale facilities, since bending, beam focusing and acceleration can be separated into different components. The most powerful modern particle accelerators use versions of the synchrotron design. The largest synchrotron-type accelerator, also the largest particle accelerator in the world, is the Large Hadron Collider (LHC) near Geneva, Switzerland, built in 2008 by the European Organization for Nuclear Research (CERN). It can accelerate beams of protons to an energy of 6.5 tera electronvolts (TeV or 1012 eV). Th ...
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Focus (optics)
In geometrical optics, a focus, also called an image point, is a point where light rays originating from a point on the object converge. Although the focus is conceptually a point, physically the focus has a spatial extent, called the blur circle. This non-ideal focusing may be caused by aberrations of the imaging optics. In the absence of significant aberrations, the smallest possible blur circle is the Airy disc, which is caused by diffraction from the optical system's aperture. Aberrations tend to worsen as the aperture diameter increases, while the Airy circle is smallest for large apertures. An image, or image point or region, is in focus if light from object points is converged almost as much as possible in the image, and out of focus if light is not well converged. The border between these is sometimes defined using a "circle of confusion" criterion. A principal focus or focal point is a special focus: * For a lens, or a spherical or parabolic mirror, it is a point ...
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Beam Divergence
In electromagnetics, especially in optics, beam divergence is an angular measure of the increase in beam diameter or radius with distance from the optical aperture or antenna aperture from which the beam emerges. The term is relevant only in the "far field", away from any focus of the beam. Practically speaking, however, the far field can commence physically close to the radiating aperture, depending on aperture diameter and the operating wavelength. Beam divergence is often used to characterize electromagnetic beams in the optical regime, for cases in which the aperture from which the beam emerges is very large with respect to the wavelength. However, it is also used in the radio frequency (RF) band for cases in which the antenna is very large relative to a wavelength. Beam divergence usually refers to a beam of circular cross section, but not necessarily so. A beam may, for example, have an elliptical cross section, in which case the orientation of the beam divergence must be ...
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Light Beam
A light beam or beam of light is a directional projection of light energy radiating from a light source. Sunlight forms a light beam (a sunbeam) when filtered through media such as clouds, foliage, or windows. To artificially produce a light beam, a lamp and a parabolic reflector is used in many lighting devices such as spotlights, car headlights, PAR Cans, and LED housings. Light from certain types of laser has the smallest possible beam divergence. Visible light beams From the side, a beam of light is only visible if part of the light is scattered by objects: tiny particles like dust, water droplets (mist, fog, rain), hail, snow, or smoke, or larger objects such as birds. If there are many objects in the light path, then it appears as a continuous beam, but if there are only a few objects, then the light is visible as a few individual bright points. In any case, this scattering of light from a beam, and the resultant visibility of a light beam from the side, is known as t ...
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Monochrome
A monochrome or monochromatic image, object or palette is composed of one color (or values of one color). Images using only shades of grey are called grayscale (typically digital) or black-and-white (typically analog). In physics, monochromatic light refers to electromagnetic radiation that contains a narrow band of wavelengths, which is a distinct concept. Application Of an image, the term monochrome is usually taken to mean the same as black and white or, more likely, grayscale, but may also be used to refer to other combinations containing only tones of a single color, such as green-and-white or green-and-red. It may also refer to sepia displaying tones from light tan to dark brown or cyanotype ("blueprint") images, and early photographic methods such as daguerreotypes, ambrotypes, and tintypes, each of which may be used to produce a monochromatic image. In computing, monochrome has two meanings: *it may mean having only one color which is either on or off (also known as ...
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Resonant Inelastic X-ray Scattering
Resonant inelastic X-ray scattering (RIXS) is an X-ray spectroscopy technique used to investigate the electronic structure of molecules and materials. Inelastic X-ray scattering is a fast developing experimental technique in which one scatters high energy, X-ray photons inelastically off matter. It is a photon-in/photon-out spectroscopy where one measures both the energy and momentum change of the scattered photon. The energy and momentum lost by the photon are transferred to intrinsic excitations of the material under study and thus RIXS provides information about those excitations. The RIXS process can also be described as a resonant X-ray Raman or resonant X-ray emission process. RIXS is a resonant technique because the energy of the incident photon is chosen such that it coincides with, and hence resonates with, one of the atomic X-ray absorption edges of the system. The resonance can greatly enhance the inelastic scattering cross section, sometimes by many orders of magni ...
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X-ray Absorption Spectroscopy
X-ray absorption spectroscopy (XAS) is a widely used technique for determining the local geometric and/or electronic structure of matter. The experiment is usually performed at synchrotron radiation facilities, which provide intense and tunable X-ray beams. Samples can be in the gas phase, solutions, or solids. Background XAS data is obtained by tuning the photon energy, using a crystalline monochromator, to a range where core electrons can be excited (0.1-100 keV). The edges are, in part, named by which core electron is excited: the principal quantum numbers n = 1, 2, and 3, correspond to the K-, L-, and M-edges, respectively. For instance, excitation of a 1s electron occurs at the K-edge, while excitation of a 2s or 2p electron occurs at an L-edge (Figure 1). There are three main regions found on a spectrum generated by XAS data which are then thought of as separate spectroscopic techniques (Figure 2): # The ''absorption threshold'' determined by the transition to the lowest ...
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Flux
Flux describes any effect that appears to pass or travel (whether it actually moves or not) through a surface or substance. Flux is a concept in applied mathematics and vector calculus which has many applications to physics. For transport phenomena, flux is a vector quantity, describing the magnitude and direction of the flow of a substance or property. In vector calculus flux is a scalar quantity, defined as the surface integral of the perpendicular component of a vector field over a surface. Terminology The word ''flux'' comes from Latin: ''fluxus'' means "flow", and ''fluere'' is "to flow". As ''fluxion'', this term was introduced into differential calculus by Isaac Newton. The concept of heat flux was a key contribution of Joseph Fourier, in the analysis of heat transfer phenomena. His seminal treatise ''Théorie analytique de la chaleur'' (''The Analytical Theory of Heat''), defines ''fluxion'' as a central quantity and proceeds to derive the now well-known express ...
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Synchrotron Radiation
Synchrotron radiation (also known as magnetobremsstrahlung radiation) is the electromagnetic radiation emitted when relativistic charged particles are subject to an acceleration perpendicular to their velocity (). It is produced artificially in some types of particle accelerators, or naturally by fast electrons moving through magnetic fields. The radiation produced in this way has a characteristic polarization and the frequencies generated can range over a large portion of the electromagnetic spectrum. Synchrotron radiation is similar to bremsstrahlung radiation, which is emitted by a charged particle when the acceleration is parallel to the direction of motion. The general term for radiation emitted by particles in a magnetic field is ''gyromagnetic radiation'', for which synchrotron radiation is the ultra-relativistic special case. Radiation emitted by charged particles moving non-relativistically in a magnetic field is called cyclotron emission. For particles in the mildly ...
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