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Sealpox Virus
Sealpox is a cutaneous (skin) condition caused by a ''Parapoxvirus'', usually affecting seal handlers who have been bitten by infected harbor or grey seals. First identified in 1969, it wasn't unequivocally proven to be transmissible to humans until 2005, though such transmission had been reported at least as early as 1987. It causes lesions that closely resemble those caused by orf. As many as 2% of seals in marine mammal rehabilitation facilities in North America may have it. See also * Farmyard pox * Tanapox * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ... References External links Virus-related cutaneous conditions Poxviruses Rare diseases Rare infectious diseases Infraspecific virus taxa {{Cutaneous-infection-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cutaneous
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/os clitoris. All mammals have some hair on their skin, even marine mammals like whales, dolphins, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parapoxvirus
''Parapoxvirus'' is a genus of viruses, in the family ''Poxviridae'', in the subfamily ''Chordopoxvirinae''. Like all members of the family Poxviridae, they are oval, relatively large, double-stranded DNA viruses. Parapoxviruses have a unique spiral coat that distinguishes them from other poxviruses. Parapoxviruses infect vertebrates, including a wide selection of mammals, and humans. Not all parapoxviruses are zoonotic. Notable zoonotic hosts of parapoxviruses include sheep, goats, and cattle. The most recent species of parapoxviruses has been found in New Zealand red deer. There are also some tentative species in the genus, including Auzduk disease virus, Chamois contagious ecthyma virus, and sealpox virus. Structure Viruses in ''Parapoxvirus'' are enveloped, with ovoid geometries. These viruses are about 140–170 nm wide and 220–300 nm long, and have a regular surface structure; tubules with a diameter of 10–20 nm form a criss-cross pattern. Genomes ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harbor Seal
The harbor (or harbour) seal (''Phoca vitulina''), also known as the common seal, is a true seal found along temperate and Arctic marine coastlines of the Northern Hemisphere. The most widely distributed species of pinniped (walruses, eared seals, and true seals), they are found in coastal waters of the northern Atlantic, Pacific Oceans, Baltic and North Seas. Harbor seals are brown, silvery white, tan, or gray, with distinctive V-shaped nostrils. An adult can attain a length of 1.85 m (6.1 ft) and a mass of up to . Blubber under the seal's skin helps to maintain body temperature. Females outlive males (30–35 years versus 20–25 years). Harbor seals stick to familiar resting spots or haulout sites, generally rocky areas (although ice, sand, and mud may also be used) where they are protected from adverse weather conditions and predation, near a foraging area. Males may fight over mates under water and on land. Females bear a single pup after a nine-month gestation, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grey Seal
The grey seal (''Halichoerus grypus'') is found on both shores of the North Atlantic Ocean. In Latin Halichoerus grypus means "hook-nosed sea pig". It is a large seal of the family Phocidae, which are commonly referred to as "true seals" or "earless seals". It is the only species classified in the genus ''Halichoerus''. Its name is spelled gray seal in the US; it is also known as Atlantic seal and the horsehead seal. Taxonomy There are two recognized subspecies of this seal: The type specimen of ''H. g. grypus'' (Zoological Museum of Copenhagen specimen ZMUC M11-1525, caught off the island of Amager, Danish part of the Baltic Sea) was believed lost for many years but was rediscovered in 2016, and a DNA test showed it belonged to a Baltic Sea specimen rather than from Greenland, as had previously been assumed (because it was first described in Otto Fabricius' book on the animals in Greenland: ''Fauna Groenlandica''). The name ''H. g. grypus'' was therefore transferred to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orf (disease)
Orf is a farmyard pox, a type of zoonosis. It causes small pustules in the skin of primarily sheep and goats, but can also occur on the hands of humans. A pale halo forms around a red centre. It may persist for several weeks before crusting and then either resolves or leaves a hard lump. There is usually only one lesion, but there may be many, and they are not painful. Sometimes there are swollen lymph glands. It is caused by a ''Parapoxvirus''. It can occur in humans who handle infected animals or contaminated objects. One third of cases may develop erythema multiforme. Once resolved, a person can still be infected again. Generally, treatment options are limited. Injecting the lesion with cidofovir or applying imiquimod has been tried. It is sometimes necessary to cut them out. The vaccine used in sheep to prevent orf is live and has been known to cause disease in humans. The disease is endemic in livestock herds worldwide. A recent outbreak emerged in southwest Ethiopia betw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Farmyard Pox
Farmyard pox is a group of closely related ''Parapoxviruses'' of sheep and cattle that can cause bovine papular stomatitis, orf and milker's nodule in humans. See also * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ... References Virus-related cutaneous conditions {{Cutaneous-infection-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tanapox
Tanapox (a virus from the genus ''Yatapoxvirus'') was first seen among individuals in the flood plain of the Tana River in Kenya during two epidemics (1957 and 1962) of acute febrile illness accompanied by localized skin lesions. Signs and symptoms The incubation period in human cases remains unknown, but in a person who underwent voluntary inoculation, erythema and central thickening appear by the fourth day. Most patients present a mild pre-eruptive fever that lasts 3–4 days, severe headaches and backaches, and often itching at the site where the skin lesion develops. There is initially a small nodule, without any central abrasion. This small nodule soon becomes papular and gradually enlarges to reach a maximum diameter of about 15 mm by the end of the second week of infection. The draining lymph nodes are also enlarged and tender from about the fifth day following the appearance of the skin lesion. The lesion remains mostly nodular but, ulcerates during the third week ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skin Lesion
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails). While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described. Classification of these conditions often presents many nosological challenges, since underlying causes and pathogenetics are often not known. Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology ( chronic blistering conditions), cause (skin conditions resul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poxviruses
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rare Diseases
A rare disease is any disease that affects a small percentage of the population. In some parts of the world, an orphan disease is a rare disease whose rarity means there is a lack of a market large enough to gain support and resources for discovering treatments for it, except by the government granting economically advantageous conditions to creating and selling such treatments. Orphan drugs are ones so created or sold. Most rare diseases are genetic and thus are present throughout the person's entire life, even if symptoms do not immediately appear. Many rare diseases appear early in life, and about 30% of children with rare diseases will die before reaching their fifth birthdays. With only four diagnosed patients in 27 years, ribose-5-phosphate isomerase deficiency is considered the rarest known genetic disease. No single cut-off number has been agreed upon for which a disease is considered rare. A disease may be considered rare in one part of the world, or in a particular gro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
