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Parapoxvirus
''Parapoxvirus'' is a genus of viruses, in the family ''Poxviridae'', in the subfamily ''Chordopoxvirinae''. Like all members of the family Poxviridae, they are oval, relatively large, double-stranded DNA viruses. Parapoxviruses have a unique spiral coat that distinguishes them from other poxviruses. Parapoxviruses infect vertebrates, including a wide selection of mammals, and humans. Not all parapoxviruses are zoonotic. Notable zoonotic hosts of parapoxviruses include sheep, goats, and cattle. The most recent species of parapoxviruses has been found in New Zealand red deer. There are also some tentative species in the genus, including Auzduk disease virus, Chamois contagious ecthyma virus, and sealpox virus. Structure Viruses in ''Parapoxvirus'' are enveloped, with ovoid geometries. These viruses are about 140–170 nm wide and 220–300 nm long, and have a regular surface structure; tubules with a diameter of 10–20 nm form a criss-cross pattern. Genomes ar ...
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Red Deerpox Virus
''Red deerpox virus'' (RDPV) is a species of virus in the genus ''Parapoxvirus''. It has been reported in deer in New Zealand, and in wild ruminants in Italy. In 1987, deaths among infected deer occurred on two Red Deer farms in New Zealand where secondary bacterial infections were seen alongside the lesions. In these particular cases, morbidity rates reached 100%. Viral classification RDPV was classified as a separate species due to its unique patterns of restriction enzymes. Parapoxviruses belongs to the family of viruses named ''Poxviridae'', family of double-stranded DNA viruses. ''Parapoxvirus'' is classified into the subfamily of ''Chordopoxvirinae''. Virion size Generally, viruses within the ''Poxviridae'' family have brick or oval-shaped virions. Sizes range from between 140-260 nanometres in width and 220-450 nanometres in length. They are enveloped viruses with surface tubules sometimes referred to as surface filaments. Structure ''Parapoxvirus'' virions are large ...
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Pseudocowpox Virus
Pseudocowpox is a disease caused by the Paravaccinia virus or Pseudocowpox virus, a virus of the family ''Poxviridae'' and the genus ''Parapoxvirus''. Humans can contract the virus from contact with livestock infected with Bovine papular stomatitis and the disease is common among ranchers, milkers, and veterinarians. Infection in humans will present with fever, fatigue, and lesion on the skin. Signs and symptoms Paravaccinia virus presents itself with blisters, nodules, or lesions about 4 mm in diameter, typically in the area that has made contact with livestock that is infected with bovine papular stomatitis. Lesions may begin forming as late as three weeks after contact has been made with an infected animal. In rare cases, lesions may be seen systemic. General signs of infection are also common, such as fever and fatigue. Infected livestock may present with blisters or lesions on their udders or snout. Often, however, infected livestock show little to no symptoms. Mechan ...
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Poxviridae
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymology ...
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Chordopoxvirinae
''Chordopoxvirinae'' is a subfamily of viruses in the family ''Poxviridae''. Humans, vertebrates, and arthropods serve as natural hosts. Currently, 52 species are placed in this subfamily, divided among 18 genera. Diseases associated with this subfamily include smallpox. Four genera in this subfamily contain species that infect humans: ''Molluscipoxvirus, Orthopoxvirus, Parapoxvirus'', and ''Yatapoxvirus''. Virology The virions are generally enveloped though the intracellular mature virion form of the virus, which contains a different envelope, and is also infectious. They vary in their shape depending upon the species, but are generally shaped like a brick or as an oval form similar to a rounded brick because they are wrapped by the endoplasmic reticulum. The virion is exceptionally large, around 200 nm in diameter and 300 nm in length, and carries its genome in a single, double-stranded segment of DNA. Genomes are linear, around 130-375kb in length. Lifecycle Viral r ...
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Sealpox Virus
Sealpox is a cutaneous (skin) condition caused by a ''Parapoxvirus'', usually affecting seal handlers who have been bitten by infected harbor or grey seals. First identified in 1969, it wasn't unequivocally proven to be transmissible to humans until 2005, though such transmission had been reported at least as early as 1987. It causes lesions that closely resemble those caused by orf. As many as 2% of seals in marine mammal rehabilitation facilities in North America may have it. See also * Farmyard pox * Tanapox * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ... References External links Virus-related cutaneous conditions Poxviruses Rare diseases Rare infectious diseases Infraspecific virus taxa {{Cutaneous-infection-stub ...
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Bovine Papular Stomatitis Virus
Bovine papular stomatitis is a farmyard pox caused by ''Bovine papular stomatitis virus'' (BPSV), which can spread from infected cattle to cause disease in milkers, farmers and veterinarians. Generally there is usually one or a few skin lesions typically on the hands or forearm. The disease is generally mild. BPSV is a member of the family ''Poxviridae'' and the genus ''Parapoxvirus''. Spread typically occurs by direct contact with the infected animal, but has been reported in people without direct contact. It may appear similar to foot-and-mouth disease. It occurs worldwide in cattle Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult mal .... In other animals the lesions are reddish, raised, sometimes ulcerative lesions on the lips, muzzle, and in the mouth. It usually occurs before the ...
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Orf Virus
Orf is a farmyard pox, a type of zoonosis. It causes small pustules in the skin of primarily sheep and goats, but can also occur on the hands of humans. A pale halo forms around a red centre. It may persist for several weeks before crusting and then either resolves or leaves a hard lump. There is usually only one lesion, but there may be many, and they are not painful. Sometimes there are swollen lymph glands. It is caused by a ''Parapoxvirus''. It can occur in humans who handle infected animals or contaminated objects. One third of cases may develop erythema multiforme. Once resolved, a person can still be infected again. Generally, treatment options are limited. Injecting the lesion with cidofovir or applying imiquimod has been tried. It is sometimes necessary to cut them out. The vaccine used in sheep to prevent orf is live and has been known to cause disease in humans. The disease is endemic in livestock herds worldwide. A recent outbreak emerged in southwest Ethiopia betw ...
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Sealpox Virus
Sealpox is a cutaneous (skin) condition caused by a ''Parapoxvirus'', usually affecting seal handlers who have been bitten by infected harbor or grey seals. First identified in 1969, it wasn't unequivocally proven to be transmissible to humans until 2005, though such transmission had been reported at least as early as 1987. It causes lesions that closely resemble those caused by orf. As many as 2% of seals in marine mammal rehabilitation facilities in North America may have it. See also * Farmyard pox * Tanapox * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ... References External links Virus-related cutaneous conditions Poxviruses Rare diseases Rare infectious diseases Infraspecific virus taxa {{Cutaneous-infection-stub ...
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Physical Trauma
An injury is any physiological damage to living tissue caused by immediate physical stress. An injury can occur intentionally or unintentionally and may be caused by blunt trauma, penetrating trauma, burning, toxic exposure, asphyxiation, or overexertion. Injuries can occur in any part of the body, and different symptoms are associated with different injuries. Treatment of a major injury is typically carried out by a health professional and varies greatly depending on the nature of the injury. Traffic collisions are the most common cause of accidental injury and injury-related death among humans. Injuries are distinct from chronic conditions, psychological trauma, infections, or medical procedures, though injury can be a contributing factor to any of these. Several major health organizations have established systems for the classification and description of human injuries. Occurrence Injuries may be intentional or unintentional. Intentional injuries may be acts o ...
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Gorse
''Ulex'' (commonly known as gorse, furze, or whin) is a genus of flowering plants in the family Fabaceae. The genus comprises about 20 species of thorny evergreen shrubs in the subfamily Faboideae of the pea family Fabaceae. The species are native to parts of western Europe and northwest Africa, with the majority of species in Iberia. Gorse is closely related to the brooms and like them has green stems and very small leaves and is adapted to dry growing conditions. However it differs in its extreme thorniness, the shoots being modified into branched thorns long, which almost wholly replace the leaves as the plant's functioning photosynthetic organs. The leaves of young plants are trifoliate, but in mature plants they are reduced to scales or small spines. All the species have yellow flowers, generally showy, some with a very long flowering season. Species The greatest diversity of ''Ulex'' species is found in the Iberian Peninsula, and most species have narrow distributio ...
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Mean
There are several kinds of mean in mathematics, especially in statistics. Each mean serves to summarize a given group of data, often to better understand the overall value (magnitude and sign) of a given data set. For a data set, the ''arithmetic mean'', also known as "arithmetic average", is a measure of central tendency of a finite set of numbers: specifically, the sum of the values divided by the number of values. The arithmetic mean of a set of numbers ''x''1, ''x''2, ..., x''n'' is typically denoted using an overhead bar, \bar. If the data set were based on a series of observations obtained by sampling from a statistical population, the arithmetic mean is the ''sample mean'' (\bar) to distinguish it from the mean, or expected value, of the underlying distribution, the ''population mean'' (denoted \mu or \mu_x).Underhill, L.G.; Bradfield d. (1998) ''Introstat'', Juta and Company Ltd.p. 181/ref> Outside probability and statistics, a wide range of other notions of mean are o ...
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