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Sensing Of Phage-triggered Ion Cascades
Sensing of phage-triggered ion cascades (SEPTIC) is a prompt bacterium identification method based on fluctuation-enhanced sensing in fluid medium. The advantages of SEPTIC are the specificity and speed (needs only a few minutes) offered by the characteristics of phage infection, the sensitivity due to fluctuation-enhanced sensing, and durability originating from the robustness of phages. An idealistic SEPTIC device may be as small as a pen and maybe able to identify a library of different bacteria within a few minutes measurement window. The mechanism SEPTIC utilizes bacteriophages as indicators to trigger an ionic response by the bacteria during phage infection. Microscopic metal electrodes detect the random fluctuations of the electrochemical potential due to the stochastic fluctuations of the ionic concentration gradient caused by the phage infection of bacteria. The electrode pair in the electrolyte with different local ion concentrations at the vicinity of electrodes form an ...
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Fluctuation-enhanced Sensing
Fluctuation-enhanced sensing (FES) is a specific type of chemical or biological sensing where the stochastic component, ''noise'', of the sensor signal is analyzed. The stages following the sensor in a FES system typically contain filters and preamplifier(s) to extract and amplify the stochastic signal components, which are usually microscopic temporal fluctuations that are orders of magnitude weaker than the sensor signal. Then selected statistical properties of the amplified ''noise'' are analyzed, and a corresponding pattern is generated as the stochastic fingerprint of the sensed agent. Often the power density spectrum of the stochastic signal is used as output pattern however FES has been proven effective with more advanced methods, too, such as higher-order statistics. History During the 1990s, several authors (for example, Bruno Neri and coworkers, Peter Gottwald and Bela Szentpali) had proposed using the spectrum of measured noise to obtain information about ambient chemic ...
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Bacteriophage
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. Their genomes may encode as few as four genes (e.g. MS2) and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm. Bacteriophages are among the most common and diverse entities in the biosphere. Bacteriophages are ubiquitous viruses, found wherever bacteria exist. It is estimated there are more than 1031 bacteriophages on the planet, more than every other organism on Earth, including bacteria, combined. Viruses are the most abundant biological entity in the water column of the world's oceans, and the second largest component of biom ...
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Electrochemical Cell
An electrochemical cell is a device capable of either generating electrical energy from chemical reactions or using electrical energy to cause chemical reactions. The electrochemical cells which generate an electric current are called voltaic or galvanic cells and those that generate chemical reactions, via electrolysis for example, are called electrolytic cells. A common example of a galvanic cell is a standard 1.5 volt cell meant for consumer use. A ''battery'' consists of one or more cells, connected in parallel, series or series-and-parallel pattern. Electrolytic cell An electrolytic cell is an electrochemical cell that drives a non-spontaneous redox reaction through the application of electrical energy. They are often used to decompose chemical compounds, in a process called electrolysis—the Greek word lysis means ''to break up''. Important examples of electrolysis are the decomposition of water into hydrogen and oxygen, and bauxite into aluminium and other chemic ...
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Noise (electronics)
In electronics, noise is an unwanted disturbance in an electrical signal. Noise generated by electronic devices varies greatly as it is produced by several different effects. In particular, noise is inherent in physics, and central to thermodynamics. Any conductor with electrical resistance will generate thermal noise inherently. The final elimination of thermal noise in electronics can only be achieved cryogenically, and even then quantum noise would remain inherent. Electronic noise is a common component of noise in signal processing. In communication systems, noise is an error or undesired random disturbance of a useful information signal in a communication channel. The noise is a summation of unwanted or disturbing energy from natural and sometimes man-made sources. Noise is, however, typically distinguished from interference, for example in the signal-to-noise ratio (SNR), signal-to-interference ratio (SIR) and signal-to-noise plus interference ratio (SNIR) measu ...
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Spectral Density
The power spectrum S_(f) of a time series x(t) describes the distribution of power into frequency components composing that signal. According to Fourier analysis, any physical signal can be decomposed into a number of discrete frequencies, or a spectrum of frequencies over a continuous range. The statistical average of a certain signal or sort of signal (including noise) as analyzed in terms of its frequency content, is called its spectrum. When the energy of the signal is concentrated around a finite time interval, especially if its total energy is finite, one may compute the energy spectral density. More commonly used is the power spectral density (or simply power spectrum), which applies to signals existing over ''all'' time, or over a time period large enough (especially in relation to the duration of a measurement) that it could as well have been over an infinite time interval. The power spectral density (PSD) then refers to the spectral energy distribution that would be ...
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1/f Noise
Pink noise or noise is a signal or process with a frequency spectrum such that the power spectral density (power per frequency interval) is inversely proportional to the frequency of the signal. In pink noise, each octave interval (halving or doubling in frequency) carries an equal amount of noise energy. Pink noise sounds like a waterfall. It is often used to tune loudspeaker systems in professional audio. Pink noise is one of the most commonly observed signals in biological systems. The name arises from the pink appearance of visible light with this power spectrum. This is in contrast with white noise which has equal intensity per frequency interval. Definition Within the scientific literature, the term 1/f noise is sometimes used loosely to refer to any noise with a power spectral density of the form S(f) \propto \frac, where ''f'' is frequency, and 0 < α < 2, with exponent α usually close to 1. One-dimensional signals with α = 1 are usually called pink noise. The f ...
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Texas A&M University
Texas A&M University (Texas A&M, A&M, or TAMU) is a public, land-grant, research university in College Station, Texas. It was founded in 1876 and became the flagship institution of the Texas A&M University System in 1948. As of late 2021, Texas A&M has the largest student body in the United States, and is the only university in Texas to hold simultaneous designations as a land, sea, and space grant institution. In 2001, it was inducted into the Association of American Universities. The university's students, alumni, and sports teams are known as Aggies, and its athletes compete in eighteen varsity sports as a member of the Southeastern Conference. The university was the first public higher-education institution in Texas; it opened for classes on October 4, 1876, as the Agricultural and Mechanical College of Texas (A.M.C.) under the provisions of the 1862 Morrill Land-Grant Act. In the following decades, the college grew in size and scope, expanding to its largest enrol ...
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Sergey M
Sergey may refer to: * Sergey (name), a Russian given name (including a list of people with the name) * Sergey, Switzerland, a municipality in Switzerland * ''Sergey'' (wasp), a genus in subfamily Doryctinae The Doryctinae or doryctine wasps are a large subfamily of braconid parasitic wasps (Braconidae). Numerous genera and species formerly unknown to science are being described every year. This subfamily is presumably part of a clade containing o ...
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United States Navy
The United States Navy (USN) is the maritime service branch of the United States Armed Forces and one of the eight uniformed services of the United States. It is the largest and most powerful navy in the world, with the estimated tonnage of its active battle fleet alone exceeding the next 13 navies combined, including 11 allies or partner nations of the United States as of 2015. It has the highest combined battle fleet tonnage (4,635,628 tonnes as of 2019) and the world's largest aircraft carrier fleet, with eleven in service, two new carriers under construction, and five other carriers planned. With 336,978 personnel on active duty and 101,583 in the Ready Reserve, the United States Navy is the third largest of the United States military service branches in terms of personnel. It has 290 deployable combat vessels and more than 2,623 operational aircraft . The United States Navy traces its origins to the Continental Navy, which was established during the American Revo ...
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Biological Techniques And Tools
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the scientific meth ...
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