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Scabies
Scabies (; also sometimes known as the seven-year itch) is a contagious human skin infestation by the tiny (0.2–0.45 mm) mite ''Sarcoptes scabiei'', variety ''hominis''. The word is from . The most common symptoms are severe itchiness and a papular, pimple-like rash. Occasionally, tiny burrows may appear on the skin. In a first-ever infection, the infected person usually develops symptoms within two to six weeks. During a second infection, symptoms may begin within 24 hours. These symptoms can be present across most of the body or just in certain areas such as the wrists, between fingers, or along the waistline. The head may be affected, but this is typically only in young children. The itch is often worse at night. Scratching may cause skin breakdown and an additional bacterial infection in the skin. Various names have been given to this condition and the name 'seven year itch' has been recorded in many documents from the 1800's. Although the 1952 The_Seven_Year_Itch_( ...
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Ivermectin
Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis. It works through many mechanisms to kill the targeted parasites, and can be taken by mouth, or applied to the skin for external infestations. It belongs to the avermectin family of medications. William Campbell and Satoshi Ōmura were awarded the 2015 Nobel Prize in Physiology or Medicine for its discovery and applications. It is on the World Health Organization's List of Essential Medicines, and is approved by the US Food and Drug Administration (FDA) as an antiparasitic agent. In 2022, it was the 314th most commonly prescribed medication in the United States, with more than 200,000 prescriptions. It is available as ...
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Sarcoptic Mange
Mange () is a type of skin disease caused by parasitic mites. Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection, is sometimes reserved for pathological mite-infestation of nonhuman mammals. Thus, mange includes mite-associated skin disease in domestic mammals (cats and dogs), in livestock (such as sheep scab), and in wild mammals (for example, foxes, coyotes, cougars, Tasmanian devils, and wombats). Severe mange caused by mites has been observed in wild bears. Since mites belong to the arachnid subclass Acari (also called Acarina), another term for mite infestation is acariasis. Parasitic mites that cause mange in mammals embed themselves in either skin or hair follicles in the animal, depending upon their genus. '' Sarcoptes'' spp. burrow into skin, while ''Demodex'' spp. live in follicles. In humans, these two types of mite infections, whi ...
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Itchiness
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex, whereas itches leads to a scratch reflex. Unmyelinated nerve fibers for itches and pain both originate in the skin. Information for them is conveyed centrally in two distinct systems that both use the same nerve bundle and spinothalamic tract. Classification Most commonly, an itch is felt in one place. If it is felt all over the body, then it is called ''generalized itch'' or ''generalized pruritus''. Generalized itch is infrequently a symptom of a serious underlying condition, such as cholestatic liver disease. If the sensation of itching persists for six weeks or longer, then it is called ''chronic itch'' or ''ch ...
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Sarcoptes Scabiei
''Sarcoptes scabiei'' (/sɑː''r''ˈkɒptiːz skeɪˈbiːaɪ/ Traditional English pronunciation of Latin) or the itch mite is a parasite, parasitic mite found in all parts of the world that burrows into skin and causes scabies. Humans become Infestation, infested by ''Sarcoptes scabiei'' var. ''hominis''; other mammals can be infested with different varieties of the mite. They include wild and domesticated dogs and cats (in which it is one cause of mange), ungulates, wild boars, bovids, wombats, koalas, and great apes. The Italian biologists Giovanni Cosimo Bonomo and Diacinto Cestoni showed in the 17th century that scabies is caused by ''Sarcoptes scabiei''; this discovery of the itch mite in 1687 marked scabies as the first disease of humans with a known microscopic causative agent. The disease produces intense, itchy skin rashes when the impregnated female tunnels into the stratum corneum of the skin and deposits egg (biology), eggs in the burrow. The larvae, which hatch in t ...
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Pruritus
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex, whereas itches leads to a scratch reflex. Unmyelinated nerve fibers for itches and pain both originate in the skin. Information for them is conveyed centrally in two distinct systems that both use the same nerve bundle and spinothalamic tract. Classification Most commonly, an itch is felt in one place. If it is felt all over the body, then it is called ''generalized itch'' or ''generalized pruritus''. Generalized itch is infrequently a symptom of a serious underlying condition, such as cholestatic liver disease. If the sensation of itching persists for six weeks or longer, then it is called ''chronic itch'' or ''ch ...
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Lindane
Lindane, also known as ''gamma''-hexachlorocyclohexane (γ-HCH), gammaxene, Gammallin and benzene hexachloride (BHC), is an organochlorine chemical and an isomer of hexachlorocyclohexane that has been used both as an agricultural insecticide and as a pharmaceutical treatment for lice and scabies. Lindane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABAA receptor-chloride channel complex at the picrotoxin binding site. In humans, lindane affects the nervous system, liver, and kidneys, and may well be a carcinogen. Whether lindane is an endocrine disruptor is unclear. The World Health Organization classifies lindane as "moderately hazardous", and its international trade is restricted and regulated under the Rotterdam Convention on Prior Informed Consent.World Health Organization''The WHO Recommended Classification of Pesticides by Hazard'' 2005. In 2009, the production and agricultural use of lindane was banned under the Stock ...
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Permethrin
Permethrin is a medication and an insecticide. As a medication, it is used to treat scabies and lice. It is applied to the skin as a cream or lotion. As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them. Side effects include rash and irritation where it is Topical medication, applied. Use during pregnancy appears to be safe, and it is approved for use on and around people over the age of two months in the United States. Permethrin is in the pyrethroid family of medications. It works by disrupting the function of the neurons of lice and scabies mites. Permethrin was discovered in 1972. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. In 2022, it was the 351st most commonly prescribed medication in the United States, with more than 40,000 prescriptions. Uses Insecticide * In agriculture, to protect crops (a drawback is that it is lethal to bees) * In agricu ...
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Burrow
file:Chipmunk-burrow (exits).jpg, An eastern chipmunk at the entrance of its burrow A burrow is a hole or tunnel excavated into the ground by an animal to construct a space suitable for habitation or temporary refuge, or as a byproduct of Animal locomotion, locomotion. Burrows provide a form of shelter against predation and exposure to the elements, and can be found in nearly every biome and among various biological interactions. Many animal species are known to form burrows. These species range from small amphipods, to very large vertebrate species such as the polar bear. Burrows can be constructed into a wide variety of substrates and can range in complexity from a simple tube a few centimeters long to a complex network of interconnecting tunnels and chambers hundreds or thousands of meters in total length; an example of the latter level of complexity, a well-developed burrow, would be a rabbit Warren (burrow), warren. Vertebrate burrows A large variety of vertebrates constru ...
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Mite
Mites are small arachnids (eight-legged arthropods) of two large orders, the Acariformes and the Parasitiformes, which were historically grouped together in the subclass Acari. However, most recent genetic analyses do not recover the two as each other's closest relative within Arachnida, rendering the group invalid as a clade. Most mites are tiny, less than in length, and have a simple, unsegmented body plan. The small size of most species makes them easily overlooked; some species live in water, many live in soil as decomposers, others live on plants, sometimes creating galls, while others are Predation, predators or Parasitism, parasites. This last type includes the commercially destructive ''Varroa'' parasite of honey bees, as well as scabies mites of humans. Most species are harmless to humans, but a few are associated with allergies or may transmit diseases. The scientific discipline devoted to the study of mites is called acarology. Evolution and taxonomy Mites are not ...
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Pyoderma
Pyoderma means any skin disease that is pyogenic (has pus). These include superficial bacterial infections such as impetigo, impetigo contagiosa, ecthyma, folliculitis, Bockhart's impetigo, furuncle, carbuncle, tropical ulcer, etc.Page 348 in: Autoimmune conditions include pyoderma gangrenosum. Pyoderma affects more than 111 million children worldwide, making it one of the three most common skin disorders in children along with scabies and tinea. See also * List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function o ... References External links Dermatologic terminology {{Cutaneous-infection-stub ...
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Developing World
A developing country is a sovereign state with a less-developed industrial base and a lower Human Development Index (HDI) relative to developed countries. However, this definition is not universally agreed upon. There is also no clear agreement on which countries fit this category. The terms low-and middle-income country (LMIC) and newly emerging economy (NEE) are often used interchangeably but they refer only to the economy of the countries. The World Bank classifies the world's economies into four groups, based on gross national income per capita: high-, upper-middle-, lower-middle-, and low-income countries. Least developed countries, landlocked developing countries, and small island developing states are all sub-groupings of developing countries. Countries on the other end of the spectrum are usually referred to as high-income countries or developed countries. There are controversies over the terms' use, as some feel that it perpetuates an outdated concept of "us" and ...
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Tropical Climate
Tropical climate is the first of the five major climate groups in the Köppen climate classification identified with the letter A. Tropical climates are defined by a monthly average temperature of or higher in the coolest month, featuring hot temperatures and high humidity all year-round. Annual precipitation is often abundant in tropical climates, and shows a seasonal rhythm but may have seasonal dryness to varying degrees. There are normally only two seasons in tropical climates, a wet (rainy/monsoon) season and a dry season. The annual temperature range in tropical climates is normally very small. Sunlight is intense in these climates. There are three basic types of tropical climates within the tropical climate group: tropical rainforest climate (Af), tropical monsoon climate (Am) and Tropical savanna climate, tropical savanna or tropical wet and dry climate (Aw for dry winters, and As for dry summers), which are classified and distinguished by the precipitation levels of the ...
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