Pupillometer
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Pupillometer
Pupilometer, also spelled pupillometer, is a name for two different devices—one used to measure the pupillary light reflex, and the other used in ophthalmology, which measures the distance between pupils through visual stimuli. Automated Pupillometry An automated pupillometer is a portable, handheld device that provides a reliable and objective measurement of pupillary size, symmetry, and reactivity through measurement of the pupillary light reflex. Independent of examiner, an automated pupillometer eliminates variability and subjectivity, expressing pupil reactivity numerically so that both pupil size and reactivity can be trended for changes, just like other vital signs. An automated pupillometer also provides a reliable and effective way to quantitatively classify and trend the pupil light response. Using automated pupillometers and algorithms, NeurOptics' Neurological Pupil index (NPi) can offer a consolidated parametric approach to mitigate subjectivity. The NPi and automa ...
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Neurological Pupil Index
Clinicians routinely check the pupils of critically injured and ill patients to monitor neurological status. However, manual pupil measurements (performed using a penlight or ophthalmoscope) have been shown to be subjective, inaccurate, and not repeatable or consistent. Automated assessment of the pupillary light reflex has emerged as an objective means of measuring pupillary reactivity across a range of neurological diseases, including stroke, traumatic brain injury and edema, tumoral herniation syndromes, and sports or war injuries. Automated pupillometers are used to assess an array of objective pupillary variables including size, constriction velocity, latency, and dilation velocity, which are normalized and standardized to compute an indexed score such as the Neurological Pupil index (NPi). Pupillary evaluation Pupillary evaluation involves the assessment of two components—pupil size and reactivity to light. * Pupil size is traditionally measured using a pupil gauge to e ...
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Neurological Pupil Index (NPi)
Clinicians routinely check the pupils of critically injured and ill patients to monitor neurological status. However, manual pupil measurements (performed using a penlight or ophthalmoscope) have been shown to be subjective, inaccurate, and not repeatable or consistent. Automated assessment of the pupillary light reflex has emerged as an objective means of measuring pupillary reactivity across a range of neurological diseases, including stroke, traumatic brain injury and edema, tumoral herniation syndromes, and sports or war injuries. Automated pupillometers are used to assess an array of objective pupillary variables including size, constriction velocity, latency, and dilation velocity, which are normalized and standardized to compute an indexed score such as the Neurological Pupil index (NPi). Pupillary evaluation Pupillary evaluation involves the assessment of two components—pupil size and reactivity to light. * Pupil size is traditionally measured using a pupil gauge to esti ...
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Pupillometry
Pupillometry, the measurement of pupil size and reactivity, is a key part of the clinical neurological exam for patients with a wide variety of neurological injuries. It is also used in psychology. Pupillometry in critical care For more than 100 years, clinicians have evaluated the pupils of patients with suspected or known brain injury or impaired consciousness to monitor neurological status and trends, checking for pupil size and reactivity to light. In fact, before the advent of electricity, doctors checked a patient’s reaction to light using a candle. Today, clinicians routinely evaluate pupils as a component of the neurological examination and monitoring of critically ill patients, including patients with traumatic brain injury and stroke. In 2019, the first smartphone based pupillometer was released as an accurate and economical way to objectively determine pupil size and dynamic response. Patient care and outcome Numerous studies have shown the importance of pupil eval ...
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Syphilis
Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter) though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. In latent syphilis, which can last for years, there are few or no symptoms. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. Syphilis has been known as "the great imitator" as it may cause symptoms similar to many other diseases. Syphilis is most commonly spread through sexual activity. It may also be transmi ...
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Psychophysiology
Psychophysiology (from Ancient Greek, Greek , ''psȳkhē'', "breath, life, soul"; , ''physis'', "nature, origin"; and , ''wiktionary:-logia, -logia'') is the branch of psychology that is concerned with the physiology, physiological bases of psychology, psychological processes. While psychophysiology was a general broad field of research in the 1960s and 1970s, it has now become quite specialized, based on methods, topic of studies and scientific traditions. Methods vary as combinations of electrophysiological methods (such as EEG), neuroimaging (MRI, Positron emission tomography, PET), and neurochemistry. Topics have branched into subspecializations such as social, sport, cognitive, cardiovascular, clinical and other branches of psychophysiology. Background Some people have difficulty distinguishing a psychophysiologist from a Physiological psychology, physiological psychologist, two very different perspectives. Psychologists are interested in why we may fear spiders and physio ...
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Pupil
The pupil is a black hole located in the center of the iris of the eye that allows light to strike the retina.Cassin, B. and Solomon, S. (1990) ''Dictionary of Eye Terminology''. Gainesville, Florida: Triad Publishing Company. It appears black because light rays entering the pupil are either absorbed by the tissues inside the eye directly, or absorbed after diffuse reflections within the eye that mostly miss exiting the narrow pupil. The term "pupil" was coined by Gerard of Cremona. In humans, the pupil is round, but its shape varies between species; some cats, reptiles, and foxes have vertical slit pupils, goats have horizontally oriented pupils, and some catfish have annular types. In optical terms, the anatomical pupil is the eye's aperture and the iris is the aperture stop. The image of the pupil as seen from outside the eye is the entrance pupil, which does not exactly correspond to the location and size of the physical pupil because it is magnified by the cornea. On the ...
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Television
Television, sometimes shortened to TV, is a telecommunication medium for transmitting moving images and sound. The term can refer to a television set, or the medium of television transmission. Television is a mass medium for advertising, entertainment, news, and sports. Television became available in crude experimental forms in the late 1920s, but only after several years of further development was the new technology marketed to consumers. After World War II, an improved form of black-and-white television broadcasting became popular in the United Kingdom and the United States, and television sets became commonplace in homes, businesses, and institutions. During the 1950s, television was the primary medium for influencing public opinion.Diggs-Brown, Barbara (2011''Strategic Public Relations: Audience Focused Practice''p. 48 In the mid-1960s, color broadcasting was introduced in the U.S. and most other developed countries. The availability of various types of archival st ...
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Marketing Research
Marketing research is the systematic gathering, recording, and analysis of qualitative and quantitative data about issues relating to marketing products and services. The goal is to identify and assess how changing elements of the marketing mix impacts customer behavior. This involves specifying the data required to address these issues, then designing the method for collecting information, managing and implementing the data collection process. After analyzing the data collected, these results and findings, including their implications, are forwarded to those empowered to act on them. Market research, marketing research, and marketing are a sequence of business activities; sometimes these are handled informally. The field of ''marketing research'' is much older than that of ''market research''. Although both involve consumers, ''Marketing'' research is concerned specifically about marketing processes, such as advertising effectiveness and salesforce effectiveness, while ''mark ...
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Penlight
A flashlight ( US, Canada) or torch ( UK, Australia) is a portable hand-held electric lamp. Formerly, the light source typically was a miniature incandescent light bulb, but these have been displaced by light-emitting diodes (LEDs) since the mid-2000s. A typical flashlight consists of the light source mounted in a reflector, a transparent cover (sometimes combined with a lens) to protect the light source and reflector, a battery, and a switch, all enclosed in a case. The invention of the dry cell and miniature incandescent electric lamps made the first battery-powered flashlights possible around 1899. Today, flashlights use mostly light-emitting diodes and run on disposable or rechargeable batteries. Some are powered by the user turning a crank, shaking the lamp, or squeezing it. Some have solar panels to recharge the battery. Flashlights are used as a light source outdoors, in places without permanently installed lighting, during power outages, or when a portable light sou ...
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Pupillary Light Reflex
The pupillary light reflex (PLR) or photopupillary reflex is a reflex that controls the diameter of the pupil, in response to the intensity (luminance) of light that falls on the retinal ganglion cells of the retina in the back of the eye, thereby assisting in adaptation of vision to various levels of lightness/darkness. A greater intensity of light causes the pupil to constrict ( miosis/myosis; thereby allowing less light in), whereas a lower intensity of light causes the pupil to dilate ( mydriasis, expansion; thereby allowing more light in). Thus, the pupillary light reflex regulates the intensity of light entering the eye. Light shone into one eye will cause both pupils to constrict. Terminology The pupil is the dark circular opening in the center of the iris and is where light enters the eye. By analogy with a camera, the pupil is equivalent to aperture, whereas the iris is equivalent to the diaphragm. It may be helpful to consider the ''Pupillary reflex'' as an Iris' refle ...
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Argyll Robertson Pupil
Argyll Robertson pupils (AR pupils) are bilateral small pupils that reduce in size on a near object (i.e., they accommodate), but do ''not'' constrict when exposed to bright light (i.e., they do not react). They are a highly specific sign of neurosyphilis; however, Argyll Robertson pupils may also be a sign of diabetic neuropathy. In general, pupils that accommodate but do not react are said to show light-near dissociation (i.e., it is the absence of a miotic reaction to light, both direct and consensual, with the preservation of a miotic reaction to near stimulus (accommodation/convergence). AR pupils are extremely uncommon in the developed world. There is continued interest in the underlying pathophysiology, but the scarcity of cases makes ongoing research difficult. Pathophysiology The two different types of near response are caused by different underlying disease processes. ''Adie's pupil'' is caused by damage to ''peripheral'' pathways to the pupil (parasympathetic neuro ...
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