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Pulvinar Nuclei
The pulvinar nuclei or nuclei of the pulvinar (nuclei pulvinares) are the nuclei ( cell bodies of neurons) located in the thalamus (a part of the vertebrate brain). As a group they make up the collection called the pulvinar of the thalamus (pulvinar thalami), usually just called the pulvinar. The pulvinar is usually grouped as one of the ''lateral thalamic nuclei'' in rodents and carnivores, and stands as an independent complex in primates. Pulvinar acts as an association nucleus that, along with medial dorsal nucleus, connected with parietal, occipital, and temporal lobes, but the function is largely unknown. No distinctive syndrome or obvious sensory deficit can be linked to either one. Structure By convention, the pulvinar is divided into four nuclei: Their connectomic details are as follows: * The ''lateral'' and ''inferior'' pulvinar nuclei have widespread connections with early visual cortical areas. * The dorsal part of the ''lateral'' pulvinar nucleus predominant ...
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Midline Nuclear Group
The midline nuclear group (or midline thalamic nuclei) is a region of the thalamus consisting of the following nuclei: * Paraventricular thalamus, paraventricular nucleus of thalamus (''nucleus paraventricularis thalami'') - not to be confused with paraventricular nucleus of hypothalamus * paratenial nucleus (''nucleus parataenialis'') * nucleus reuniens (also known as the medioventral nucleus) * rhomboidal nucleus (''nucleus commissuralis rhomboidalis'') * subfascicular nucleus (''nucleus subfascicularis'') The List of regions in the human brain#Thalamus, midline nuclei are often called "nonspecific" in that they project widely to the cortex and elsewhere. This has led to the assumption that they may be involved in general functions such as alerting. However, anatomical connections might suggest more specific functions, with the paraventricular and paratenial nuclei involved in viscero-limbic functions, and the reuniens and rhomboid nuclei involved in multimodal sensory processin ...
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Brain
The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for special senses such as visual perception, vision, hearing, and olfaction. Being the most specialized organ, it is responsible for receiving information from the sensory nervous system, processing that information (thought, cognition, and intelligence) and the coordination of motor control (muscle activity and endocrine system). While invertebrate brains arise from paired segmental ganglia (each of which is only responsible for the respective segmentation (biology), body segment) of the ventral nerve cord, vertebrate brains develop axially from the midline dorsal nerve cord as a brain vesicle, vesicular enlargement at the rostral (anatomical term), rostral end of the neural tube, with centralized control over all body segments. All vertebr ...
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Superior Colliculus
In neuroanatomy, the superior colliculus () is a structure lying on the tectum, roof of the mammalian midbrain. In non-mammalian vertebrates, the Homology (biology), homologous structure is known as the optic tectum or optic lobe. The adjective form ''tectum, tectal'' is commonly used for both structures. In mammals, the superior colliculus forms a major component of the midbrain. It is a paired structure and together with the paired inferior colliculi forms the corpora quadrigemina. The superior colliculus is a layered structure, with a pattern that is similar in all mammals. The layers can be grouped into the superficial layers (retinal nerve fiber layer, stratum opticum and above) and the deeper remaining layers. Neurons in the superficial layers receive direct input from the retina and respond almost exclusively to visual stimuli. Many neurons in the deeper layers also respond to other modalities, and some respond to stimuli in multiple modalities. The deeper layers also conta ...
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Prefrontal Cortex
In mammalian brain anatomy, the prefrontal cortex (PFC) covers the front part of the frontal lobe of the cerebral cortex. It is the association cortex in the frontal lobe. The PFC contains the Brodmann areas BA8, BA9, BA10, BA11, BA12, BA13, BA14, BA24, BA25, BA32, BA44, BA45, BA46, and BA47. This brain region is involved in a wide range of higher-order cognitive functions, including speech formation (Broca's area), gaze ( frontal eye fields), working memory ( dorsolateral prefrontal cortex), and risk processing (e.g. ventromedial prefrontal cortex). The basic activity of this brain region is considered to be orchestration of thoughts and actions in accordance with internal goals. Many authors have indicated an integral link between a person's will to live, personality, and the functions of the prefrontal cortex. This brain region has been implicated in executive functions, such as planning, decision making, working memory, personality expression, moderating ...
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Premotor
The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and humans. The functions of the premotor cortex are diverse and not fully understood. It projects directly to the spinal cord and therefore may play a role in the direct control of behavior, with a relative emphasis on the trunk muscles of the body. It may also play a role in planning movement, in the spatial guidance of movement, in the sensory guidance of movement, in understanding the actions of others, and in using abstract rules to perform specific tasks. Different subregions of the premotor cortex have different properties and presumably emphasize different functions. Nerve signals generated in the premotor cortex cause much more complex patterns of movement than the discrete patterns generated in the primary motor cortex. Structure The pre ...
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Cingulate Cortex
The cingulate cortex is a part of the brain situated in the medial aspect of the cerebral cortex. The cingulate cortex includes the entire cingulate gyrus, which lies immediately above the corpus callosum, and the continuation of this in the cingulate sulcus. The cingulate cortex is usually considered part of the limbic lobe. It receives inputs from the thalamus and the neocortex, and projects to the entorhinal cortex via the cingulum. It is an integral part of the limbic system, which is involved with emotion formation and processing, learning, and memory. The combination of these three functions makes the cingulate gyrus highly influential in linking motivational outcomes to behavior (e.g. a certain action induced a positive emotional response, which results in learning). This role makes the cingulate cortex highly important in disorders such as depression and schizophrenia. It also plays a role in executive function and respiratory control. Structure Based on cerebral c ...
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Dorsal Stream
The two-streams hypothesis is a model of the neural processing of vision as well as hearing. The hypothesis, given its initial characterisation in a paper by David Milner and Melvyn A. Goodale in 1992, argues that humans possess two distinct visual systems. Recently there seems to be evidence of two distinct auditory systems as well. As visual information exits the occipital lobe, and as sound leaves the phonological network, it follows two main pathways, or "streams". The ventral stream (also known as the "what pathway") leads to the temporal lobe, which is involved with object and visual identification and recognition. The dorsal stream (or, "where pathway") leads to the parietal lobe, which is involved with processing the object's spatial location relative to the viewer and with speech repetition. History Several researchers had proposed similar ideas previously. The authors themselves credit the inspiration of work on blindsight by Weiskrantz, and previous neuroscientifi ...
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Posterior Parietal
The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus. The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin (touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe. Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure – the cortical homunculus (Latin: "little man") in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them. The superior parietal lobule and i ...
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Visual Cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and then reaches the visual cortex. The area of the visual cortex that receives the sensory input from the lateral geniculate nucleus is the primary visual cortex, also known as visual area 1 ( V1), Brodmann area 17, or the striate cortex. The extrastriate areas consist of visual areas 2, 3, 4, and 5 (also known as V2, V3, V4, and V5, or Brodmann area 18 and all Brodmann area 19). Both hemispheres of the brain include a visual cortex; the visual cortex in the left hemisphere receives signals from the right visual field, and the visual cortex in the right hemisphere receives signals from the left visual field. Introduction The primary visual cortex (V1) is located in and around the calcarine fissure in the occipital lobe. Each h ...
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Connectome
A connectome () is a comprehensive map of neural connections in the brain, and may be thought of as its " wiring diagram". These maps are available in varying levels of detail. A functional connectome shows connections between various brain regions, but not individual neurons. These are available for large animals, including mice and humans, are normally obtained by techniques such as MRI, and have a scale of millimeters. At the other extreme are neural connectomes, which show individual neurons and their interconnections. These are usually obtained by electron microscopy (EM) and have a scale of nanometers. They are only available for small creatures such as the worm ''C. Elegans'' and the fruit fly ''Drosophila melanogaster'', and small regions of mammal brains. Finally there are chemical connectomes, showing which neurons emit, and are sensitive to, a wide variety of neuromodulators. The significance of the connectome stems from the realization that the structure an ...
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Medial Pulvinar Nucleus
Medial pulvinar nucleus (''nucleus pulvinaris medialis'') is one of four traditionally anatomically distinguished nuclei of the pulvinar of the thalamus. The other three nuclei of the pulvinar are called lateral, inferior and anterior pulvinar nuclei. Connections Afferent * Medial pulvinar nucleus, together with its lateral and inferior nuclei, receives afferent input from superior colliculus. * Medial pulvinar nucleus also receives many afferent inputs from different cortical areas, including cingulate, posterior parietal, premotor and prefrontal cortical areas. This is the pattern of input connections typical for association relay nuclei of the thalamus. Efferent * Medial pulvinar nucleus sends its widespread projections to the different areas of association cortex, including cingulate, posterior parietal, premotor and prefrontal cortical areas. This is the pattern of output connections typical for association relay nuclei of the thalamus. Functions * Medi ...
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Lateral Pulvinar Nucleus
Lateral pulvinar nucleus (''nucleus pulvinaris lateralis'') is one of four traditionally anatomically distinguished nuclei of the pulvinar of the thalamus. The other three nuclei of the pulvinar are called anterior, inferior and medial pulvinar nuclei. Connections Afferent * Lateral pulvinar nucleus, together with its inferior and medial nuclei, receives afferent input from superior colliculus. * The dorsal part of the lateral pulvinar nucleus also receives afferent input from posterior parietal cortex and the dorsal stream cortical areas. Efferent * Lateral pulvinar nucleus, together with its inferior nucleus, both have projections to the early visual cortical areas. * The dorsal part of the lateral pulvinar nucleus also sends its efferent output connections to the posterior parietal cortex and the dorsal stream cortical areas. Functions * Lateral pulvinar nucleus, together with its inferior and medial nuclei, is thought to be important for the initiation ...
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