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Occupational Epidemiology
Occupational epidemiology is a subdiscipline of epidemiology that focuses on investigations of workers and the workplace. Occupational epidemiologic studies examine health outcomes among workers, and their potential association with conditions in the workplace including noise, chemicals, heat, or radiation, or work organization such as schedules. The need for evidence to inform occupational safety regulations, workers' compensation programs, and safety legislation motivated the development of public health policy, occupational epidemiology methods, and surveillance mechanisms. Occupational epidemiological research can inform risk assessments; development of standards and other risk management activities; and estimates of the co-benefits and co-harms of policies designed to reduce risk factors or conditions that can affect human health. Occupational epidemiology methods are common to methods used in environmental epidemiology. History Occupational hazards have long been recogniz ...
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Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic epidemiology, occupational epidemiology, screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. ...
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Case Series
A case series (also known as a clinical series) is a type of medical research study that tracks subjects with a known exposure, such as patients who have received a similar treatment, or examines their medical records for exposure and outcome. Case series may be ''consecutive'' or ''non-consecutive'', depending on whether all cases presenting to the reporting authors over a period were included, or only a selection. When information on ''more than three patients'' is included, the case series is considered to be a systematic investigation designed to contribute to generalizable knowledge (i.e., ''research''), and therefore submission is required to an institutional review board (IRB). Case series usually contain demographic information about the patient(s), for example, age, gender, ethnic origin. etc. Case series have a descriptive study design; unlike studies that employ an analytic design (e.g. cohort studies, case-control studies or randomized controlled trials), case series ...
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Benzene
Benzene is an organic chemical compound with the molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar ring with one hydrogen atom attached to each. Because it contains only carbon and hydrogen atoms, benzene is classed as a hydrocarbon. Benzene is a natural constituent of petroleum and is one of the elementary petrochemicals. Due to the cyclic continuous pi bonds between the carbon atoms, benzene is classed as an aromatic hydrocarbon. Benzene is a colorless and highly flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline. It is used primarily as a precursor to the manufacture of chemicals with more complex structure, such as ethylbenzene and cumene, of which billions of kilograms are produced annually. Although benzene is a major industrial chemical, it finds limited use in consumer items because of its toxicity. History Discovery The word "''benzene''" derives from "''gum benzoin''" (benzoin res ...
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Occupational Exposure Limit
An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health. It is an important tool in risk assessment and in the management of activities involving handling of dangerous substances. There are many dangerous substances for which there are no formal occupational exposure limits. In these cases, hazard banding or control banding strategies can be used to ensure safe handling. Background Occupational Exposure Limits (OELs) have been established for airborne workplace chemicals by multiple regulatory and authoritative organizations around the world for well over 60 years now. With the changing regulatory arena, shifting centers of manufacturing growth, and the move towards a more global view on occupational hygiene issues, it is important for the ...
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Cross-sectional Study
In medical research, social science, and biology, a cross-sectional study (also known as a cross-sectional analysis, transverse study, prevalence study) is a type of observational study that analyzes data from a population, or a representative subset, ''at a specific point in time''—that is, cross-sectional data. In economics, cross-sectional studies typically involve the use of cross-sectional regression, in order to sort out the existence and magnitude of causal effects of one independent variable upon a dependent variable of interest at a given point in time. They differ from time series analysis, in which the behavior of one or more economic aggregates is traced through time. In medical research, cross-sectional studies differ from case-control studies in that they aim to provide data on the entire population under study, whereas case-control studies typically include only individuals who have developed a specific condition and compare them with a matched sample, o ...
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Scientific Community
The scientific community is a diverse network of interacting scientists. It includes many " sub-communities" working on particular scientific fields, and within particular institutions; interdisciplinary and cross-institutional activities are also significant. Objectivity is expected to be achieved by the scientific method. Peer review, through discussion and debate within journals and conferences, assists in this objectivity by maintaining the quality of research methodology and interpretation of results. History of scientific communities The eighteenth century had some societies made up of men who studied nature, also known as natural philosophers and natural historians, which included even amateurs. As such these societies were more like local clubs and groups with diverse interests than actual scientific communities, which usually had interests on specialized disciplines. Though there were a few older societies of men who studied nature such as the Royal Society of London, ...
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Treatment And Control Groups
In the design of experiments, hypotheses are applied to experimental units in a treatment group. In comparative experiments, members of a control group receive a standard treatment, a placebo, or no treatment at all. There may be more than one treatment group, more than one control group, or both. A placebo control group can be used to support a double-blind study, in which some subjects are given an ineffective treatment (in medical studies typically a sugar pill) to minimize differences in the experiences of subjects in the different groups; this is done in a way that ensures no participant in the experiment (subject or experimenter) knows to which group each subject belongs. In such cases, a third, non-treatment control group can be used to measure the placebo effect directly, as the difference between the responses of placebo subjects and untreated subjects, perhaps paired by age group or other factors (such as being twins). For the conclusions drawn from the results of an e ...
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Population (statistics)
In statistics, a population is a set of similar items or events which is of interest for some question or experiment. A statistical population can be a group of existing objects (e.g. the set of all stars within the Milky Way galaxy) or a hypothetical and potentially infinite group of objects conceived as a generalization from experience (e.g. the set of all possible hands in a game of poker). A common aim of statistical analysis is to produce information about some chosen population. In statistical inference, a subset of the population (a statistical '' sample'') is chosen to represent the population in a statistical analysis. Moreover, the statistical sample must be unbiased and accurately model the population (every unit of the population has an equal chance of selection). The ratio of the size of this statistical sample to the size of the population is called a ''sampling fraction''. It is then possible to estimate the '' population parameters'' using the appropriate ...
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Disease Cluster
A disease cluster is an unusually large aggregation of a relatively uncommon medical condition or event within a particular geographical location or period. Recognition of a cluster depends on its size being seen as greater than would be expected by the play of chance. Identification of a suspected disease cluster may initially depend on anecdotal evidence. Epidemiologists and biostatisticians need to assess whether the suspected cluster corresponds to an actual increase of disease in the area. Typically, when clusters are recognized, they are reported to public health departments in the local area. If clusters are of sufficient size and importance, they may be re-evaluated as outbreaks. John Snow's pioneering investigation of the 1854 cholera outbreak in Soho, London, is seen as a classic example of the study of such a cluster. References External links Disease Clusters: An Overview introduction to a course held by the Agency for Toxic Substances and Disease Registry {{dis ...
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Longitudinal Study
A longitudinal study (or longitudinal survey, or panel study) is a research design that involves repeated observations of the same variables (e.g., people) over short or long periods of time (i.e., uses longitudinal data). It is often a type of observational study, although it can also be structured as longitudinal randomized experiment. Longitudinal studies are often used in social-personality and clinical psychology, to study rapid fluctuations in behaviors, thoughts, and emotions from moment to moment or day to day; in developmental psychology, to study developmental trends across the life span; and in sociology, to study life events throughout lifetimes or generations; and in consumer research and political polling to study consumer trends. The reason for this is that, unlike cross-sectional studies, in which different individuals with the same characteristics are compared, longitudinal studies track the same people, and so the differences observed in those people are less like ...
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Cross-sectional Study
In medical research, social science, and biology, a cross-sectional study (also known as a cross-sectional analysis, transverse study, prevalence study) is a type of observational study that analyzes data from a population, or a representative subset, ''at a specific point in time''—that is, cross-sectional data. In economics, cross-sectional studies typically involve the use of cross-sectional regression, in order to sort out the existence and magnitude of causal effects of one independent variable upon a dependent variable of interest at a given point in time. They differ from time series analysis, in which the behavior of one or more economic aggregates is traced through time. In medical research, cross-sectional studies differ from case-control studies in that they aim to provide data on the entire population under study, whereas case-control studies typically include only individuals who have developed a specific condition and compare them with a matched sample, o ...
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