Nuclear Bodies
Nuclear bodies (also known as nuclear domains, or nuclear dots) are membraneless structures found in the cell nuclei of eukaryotic cells. Nuclear bodies include Cajal bodies, the nucleolus, and promyelocytic leukemia protein (PML) nuclear bodies (also called PML oncogenic dots). Nuclear bodies also include ND10s. ND stands for nuclear domain, and 10 refers to the number of dots seen. Nuclear bodies were first seen as prominent interchromatin structures in the nuclei of malignant or hyperstimulated animal cells identified using anti-sp100 autoantibodies from primary biliary cirrhosis and subsequently the promyelocytic leukemia (PML) factor, but appear also to be elevated in many autoimmune and cancerous diseases. Nuclear dots are metabolically stable and resistant to nuclease digestion and salt extraction. A nuclear body subtype is a clastosome suggested to be a site of protein degradation. Structure Simple nuclear bodies (types I and II) and the shells of complex nuclear ...
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Nuclear Substructures
Nuclear may refer to: Physics Relating to the nucleus of the atom: *Nuclear engineering *Nuclear physics *Nuclear power *Nuclear reactor *Nuclear weapon *Nuclear medicine *Radiation therapy *Nuclear warfare Mathematics *Nuclear space *Nuclear operator *Nuclear congruence *Nuclear C*-algebra Biology Relating to the nucleus of the cell: * Nuclear DNA Society *Nuclear family, a family consisting of a pair of adults and their children Music * "Nuclear" (band), group music. * "Nuclear" (Ryan Adams song), 2002 *"Nuclear", a song by Mike Oldfield from his ''Man on the Rocks'' album * ''Nu.Clear'' (EP) by South Korean girl group CLC See also *Nucleus (other) *Nucleolus *Nucleation *Nucleic acid *Nucular ''Nucular'' is a common, proscribed pronunciation of the word "nuclear". It is a rough phonetic spelling of . The ''Oxford English Dictionary''s entry dates the word's first published appearance to 1943. Dictionary notes This is one of two con ...

Autoimmune Diseases
An autoimmune disease is a condition arising from an abnormal immune response to a functioning body part. At least 80 types of autoimmune diseases have been identified, with some evidence suggesting that there may be more than 100 types. Nearly any body part can be involved. Common symptoms can be diverse and transient, ranging from mild to severe, and generally include low grade fever and feeling tired. The cause is unknown. Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors. Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, graves' disease, inflammatory bowel disease, multiple sclerosis, alopecia areata, addison’s disease, pernicious anemia, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus. The diagnosis can be difficult to determine. Treatment depends on the type and severity of the condition. Nonsteroidal ant ...
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