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Neurochemist
Neurochemistry is the study of chemicals, including neurotransmitters and other molecules such as psychopharmaceuticals and neuropeptides, that control and influence the physiology of the nervous system. This particular field within neuroscience examines how neurochemicals influence the operation of neurons, synapses, and neural networks. Neurochemists analyze the biochemistry and molecular biology of organic compounds in the nervous system, and their roles in such neural processes including cortical plasticity, neurogenesis, and neural differentiation. History While neurochemistry as a recognized science is relatively new, the idea behind neurochemistry has been around since the 18th century. Originally, the brain had been thought to be a separate entity apart from the peripheral nervous system. Beginning in 1856, there was a string of research that refuted that idea. The chemical makeup of the brain was nearly identical to the makeup of the peripheral nervous system. The fir ...
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International Society For Neurochemistry
The International Society for Neurochemistry (ISN) is a professional society for neurochemists and neuroscientists throughout the world. History The idea of an organization like the ISN began in the mid-1950s as scientists began to devote more attention to the discipline of neurochemistry. As the field became more popular, scientists recognized that an international association would be useful in helping to propagate research among themselves. In 1962, Jordi Folch Pi and Heinrich Waelesch proposed the formation of a Provisional Organizing Committee to such a society. The committee eventually came into being in 1963 and had an international membership composed of scientists in the field. Preliminary statutes were drafted in 1965 and finalized in 1967 as the Articles of Association of the ISN.The Beginning
, The Inte ...
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ...
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Johann Ludwig Wilhelm Thudichum
Johann Ludwig Wilhelm Thudichum, also known as John Louis William Thudichum (August 27, 1829, Büdingen – September 7, 1901) was a German-born physician and biochemist. From 1847 he studied medicine at the University of Giessen, where he worked after hours in the laboratory of Justus von Liebig (1803–1873). In 1853 he moved to London, where he worked for the remainder of his career. Thudichum was a pioneer of British biochemistry, and a founder of "brain chemistry". He is credited with conducting chemical analyses of over one thousand human and animal brains. In his research, he isolated and characterized numerous compounds of the brain, such as cephalin, sphingomyelin, galactose, lactic acid and sphingosine. In 1884 he explained his findings in a publication titled "A Treatise on the Chemical Constitution of the Brain", a book that was widely criticized and rejected at the time by many in the scientific community. After his death, Thudichum's discoveries were realized ...
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American Society For Neurochemistry
The American Society for Neurochemistry (ASN) is a professional society for neurochemists and neuroscientists from North, Central, and South America and the Caribbean, whose research concerns the role and interactions of small molecules (proteins, peptides, nucleic acids, lipids, sugars) in the development, growth, function, and pathology of the nervous system. History The ASN was incorporated August 5, 1969, and is guided by a set of bylaws and standing rules that incorporate amendments to the bylaws. The first president was Donald B. Tower, Jordi Folch Pi was the second president. The current president (2013–2015) is Etty Benveniste (University of Alabama at Birmingham) and the current president elect is Babette Fuss (Richmond, Virginia). Elections are held ever 2 years to elect the next president, treasurer, secretary, and council members. Organization The officers and council members are assisted by a number of standing committees. An informal history of the ASN has b ...
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List Of Neurochemists
{{expand list, date=April 2013 This is a list of neurochemists. * David R. Brown * Fernando Garcia de Mello * Michaela Jaksch * David Nutt * Candace Pert * Juda Hirsch Quastel * John Raymond Smythies * Tilli Tansey * Johann Ludwig Wilhelm Thudichum See also * Neurochemistry * List of neuroscientists Many famous neuroscientists are from the 20th and 21st century, as neuroscience is a fairly new science. However many anatomists, physiologists, biologists, neurologists, psychiatrists and other physicians and psychologists are considered to be n ... Neurochemists ...
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Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic compound, organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80% of the catecholamine content in the brain. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor (chemistry), precursor chemical, L-DOPA, which is biosynthesis, synthesized in the brain and kidneys. Dopamine is also synthesized in plants and most animals. In the brain, dopamine functions as a neurotransmitter—a chemical released by neurons (nerve cells) to send signals to other nerve cells. Neurotransmitters are synthesized in specific regions of the brain, but affect many regions systemically. The brain includes several distinct dopaminergic pathway, dopamine pathways, one of which plays a major role in the motivational component of reward system, reward-motivated behavior. The anticipa ...
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Neurotransmitter
A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, any main body part or target cell, may be another neuron, but could also be a gland or muscle cell. Neurotransmitters are released from synaptic vesicles into the synaptic cleft where they are able to interact with neurotransmitter receptors on the target cell. The neurotransmitter's effect on the target cell is determined by the receptor it binds. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available and often require a small number of biosynthetic steps for conversion. Neurotransmitters are essential to the function of complex neural systems. The exact number of unique neurotransmitters in humans is unknown, but more than 100 have been identified. Common neurotransmitters include glutamate, GABA, acetylcholine, glycine and norepinephrine. Mechanism and cycle Synthes ...
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Neurochemical
A neurochemical is a small organic molecule or peptide that participates in neural activity. The science of neurochemistry studies the functions of neurochemicals. Prominent neurochemicals Neurotransmitters and neuromodulators *Glutamate is the most common neurotransmitter. Most neurons secrete with glutamate or GABA. Glutamate is excitatory, meaning that the release of glutamate by one cell usually causes adjacent cells to fire an action potential. (Note: Glutamate is chemically identical to the MSG commonly used to flavor food.) * GABA is an example of an inhibitory neurotransmitter. * Monoamine neurotransmitters: **Dopamine is a monoamine neurotransmitter. It plays a key role in the functioning of the limbic system, which is involved in emotional function and control. It also is involved in cognitive processes associated with movement, arousal, executive function, body temperature regulation, and pleasure and reward, and other processes. **Norepinephrine, also known as noradr ...
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Psychoactive Drug
A psychoactive drug, psychopharmaceutical, psychoactive agent or psychotropic drug is a chemical substance, that changes functions of the nervous system, and results in alterations in perception, mood, consciousness, cognition or behavior. These substances may be used medically, recreationally or spiritually to a. Purposefully improve one’s perceived performance b. Alter one's consciousness (such as with entheogens for ritual, spiritual or shamanic purposes) or c. For research. Some categories of psychoactive drugs - which are believed, by some, to have therapeutic value - may be prescribed by some physicians and other healthcare practitioners. Examples of medication categories that may contain potentially beneficial psychoactive drugs include, but are not limited to: # Anesthetics # Analgesics # Anticonvulsants # Anti-Parkinson’s medications # Medications used to treat Neuropsychiatric Disorders a. Antidepressants b. Anxiolytics c. Antipsychotics ...
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Neural Network
A neural network is a network or circuit of biological neurons, or, in a modern sense, an artificial neural network, composed of artificial neurons or nodes. Thus, a neural network is either a biological neural network, made up of biological neurons, or an artificial neural network, used for solving artificial intelligence (AI) problems. The connections of the biological neuron are modeled in artificial neural networks as weights between nodes. A positive weight reflects an excitatory connection, while negative values mean inhibitory connections. All inputs are modified by a weight and summed. This activity is referred to as a linear combination. Finally, an activation function controls the amplitude of the output. For example, an acceptable range of output is usually between 0 and 1, or it could be −1 and 1. These artificial networks may be used for predictive modeling, adaptive control and applications where they can be trained via a dataset. Self-learning resulting from e ...
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Serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction. Approximately 90% of the serotonin that the body produces is in the intestinal tract. Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) hydroxylation of the 5 position on the ring (forming the intermediate 5-hydroxytryptophan), and then decarboxylation to produce serotonin. Serotonin is primarily found in the enteric nervous system located in the gastrointestinal tract (GI tract). However, it is also produced in the central nervous system (CNS), specifically in the raphe nuclei located in the brainstem, Merkel cells located in the skin, pulmonary neuroendocrine cells and taste receptor cells in the tongue. Additionally, serotonin is stored in blood platelets and is ...
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Neuroendocrinology
Neuroendocrinology is the branch of biology (specifically of physiology) which studies the interaction between the nervous system and the endocrine system; i.e. how the brain regulates the hormonal activity in the body. The nervous and endocrine systems often act together in a process called neuroendocrine integration, to regulate the physiological processes of the human body. Neuroendocrinology arose from the recognition that the brain, especially the hypothalamus, controls secretion of pituitary gland hormones, and has subsequently expanded to investigate numerous interconnections of the endocrine and nervous systems. The endocrine system consists of numerous glands throughout the body that produce and secrete hormones of diverse chemical structure, including peptides, steroids, and neuroamines. Collectively, hormones regulate many physiological processes. The neuroendocrine system is the mechanism by which the hypothalamus maintains homeostasis, regulating reproduction, metab ...
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