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Mushroom Gene
Identified in 2014, the mushroom gene is a recessive dilution gene that affects red pigment in horses. On a chestnut base coat the horse is born a pale beige with sometimes a greyish or pinkish tint and often keeps that color when it becomes an adult, but some turn darker when an adult. On a bay base the horse is born a yellowish beige with a dark contrast stripe on the back, and as it grows older the horse will resemble a buckskin. Prevalence As of 2019, the dilution has only been found in Shetland ponies in the United Kingdom. The effect of mushroom on chestnut is very similar to silver dapple on black, especially because both silver and mushroom give a coat with no reddish tinge. Several ponies with this colour have been tested for the extension gene and results showed they were chestnut, thus verifying that it affects the "red" pigment pheomelanin. In 2019 the gene was mapped to the p.Asp201fs frameshift mutation in ''MFSD12'' on equine chromosome 7. MSDF12 (major f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dilution Gene
A dilution gene is any one of a number of genes that act to create a lighter coat color in living creatures. There are many examples of such genes: General Diluted coat colors have melanocytes, but vary from darker colors due to the concentration or type of these pigment-producing cells, not their absence. Pigment dilution, sometimes referred to as hypomelanism, has been called leucism, albinism (perfect, impartial, or dilute), ghosting, paling, and isabellinism. *Albinism describes a condition where pigment cells synthesize little or no pigment *Leucism describes a condition that creates loss of pigment cells Cats *Cat coat genetics discusses many dilution genes in cats Dogs In dogs, a mutation of the MLPH locus known as the dilute gene causes eumelanin to lighten while pheomelanin remains almost unchanged. Dogs of some breeds with the dilute gene often suffer from Colour dilution alopecia (CDA). Appearance Of the colour shades found in the coat of dogs, the light brown cau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chestnut (coat)
Chestnut is a hair coat color of horses consisting of a reddish-to-brown coat with a mane and tail the same or lighter in color than the coat. Chestnut is characterized by the absolute absence of true black hairs. It is one of the most common horse coat colors, seen in almost every breed of horse. Chestnut is a very common coat color but the wide range of shades can cause confusion. The lightest chestnuts may be mistaken for palominos, while the darkest shades can be so dark they appear black. Chestnuts have dark brown eyes and black skin, and typically are some shade of red or reddish brown. The mane, tail, and legs may be lighter or darker than the body coat, but unlike the bay they are never truly black. Like any other color of horse, chestnuts may have pink skin with white hair where there are white markings, and if such white markings include one or both eyes, the eyes may be blue. Chestnut foals may be born with pinkish skin, which darkens shortly afterwards. Chestnu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bay (horse)
Bay is a hair coat color of horses, characterized by a reddish-brown or brown body color with a black point coloration on the mane, tail, ear edges, and lower legs. Bay is one of the most common coat colors in many horse breeds. The black areas of a bay horse's hair coat are called "black points", and without them, a horse is not a bay horse. Black points may sometimes be covered by white markings; however such markings do not alter a horse's classification as "bay". Bay horses have dark skin – except under white markings, where the skin is pink. Genetically, bay occurs when a horse carries both the Agouti gene and a black base coat. While the basic genetics that create bay coloring are fairly simple, the genes themselves and the mechanisms that cause shade variations within the bay family are quite complex and, at times, disputed. The genetics of dark shades of bay are still under study. The genetic mechanism that produces seal brown has yet to be isolated. Sooty genet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Buckskin (horse)
Buckskin is a hair coat color of horses, referring to a color that resembles certain shades of tanned deerskin. Similar colors in some breeds of dogs are also called buckskin. The horse has a tan or gold colored coat with black points (mane, tail, and lower legs). Buckskin occurs as a result of the cream dilution gene acting on a bay horse. Therefore, a buckskin has the Extension, or "black base coat" (E) gene, the agouti gene (A) gene (see bay for more on the agouti gene), which restricts the black base coat to the points, and one copy of the cream gene (CCr), which lightens the red/brown color of the bay coat to a tan/gold. Buckskins should not be confused with dun-colored horses, which have the dun dilution gene, not the cream gene. Duns always have primitive markings (shoulder blade stripes, dorsal stripe, zebra stripes on legs, webbing). However, it is possible for a horse to carry both dilution genes; these are called "buckskin duns" or sometimes "dunskins." Also, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shetland Pony
The Shetland pony is a Scottish breed of pony originating in the Shetland Isles in the north of Scotland. It may stand up to at the withers. It has a heavy coat and short legs, is strong for its size, and is used for riding, driving, and pack purposes. History Shetland ponies originated in the Shetland Isles, located northeast of mainland Scotland. Small horses have been kept in the Shetland Isles since the Bronze Age. People who lived on the islands probably later crossed the native stock with ponies imported by Norse settlers. Shetland ponies also were probably influenced by the Celtic pony, brought to the islands by settlers between 2000 and 1000 BCE. The harsh climate and scarce food developed the ponies into extremely hardy animals. Shetland ponies were first used for pulling carts and for carrying peat, coal and other items, and ploughing land. Then, as the Industrial Revolution increased the need for coal in the mid-nineteenth century, thousands of Shetland ponie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silver Dapple
The silver or silver dapple (''Z'') gene is a dilution gene that affects the black base coat color and is associated with Multiple Congenital Ocular Abnormalities. It will typically dilute a black mane and tail to a silvery gray or flaxen color, and a black body to a chocolaty brown, sometimes with dapples."Horse coat color tests -Silver Dilution" from the Veterinary Genetics Lab It is responsible for a group of coat colors in horses called "silver dapple" in the west, or "taffy" in Australia. The most common colors in this category are '' |
Extension Gene
The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a G protein–coupled receptor that binds to a class of pituitary peptide hormones known as the melanocortins, which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH). It is coupled to Gαs and upregulates levels of cAMP by activating adenylyl cyclase in cells expressing this receptor. It is normally expressed in skin and melanocytes, and to a lesser degree in periaqueductal gray matter, astrocytes and leukocytes. In skin cancer, MC1R is highly expressed in melanomas but not carcinomas. MC1R is one of the key proteins involved in regulating mammalian skin color and hair color. It is located on the plasma membrane of specialized cells known as melanocytes, which produce the pigment melanin through the process of melanogenesis. It works by controlling the type of me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanocyte
Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. Function Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the skin, eyes, hair, nasal cavity, and inner ear. This melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from oxidation of already-existing melanin. There are both ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
