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Mandrake
A mandrake is the root of a plant, historically derived either from plants of the genus '' Mandragora'' found in the Mediterranean region, or from other species, such as ''Bryonia alba'', the English mandrake, which have similar properties. The plants from which the root is obtained are also called "mandrakes". Mediterranean mandrakes are perennial herbaceous plants with ovate leaves arranged in a rosette, a thick upright root, often branched, and bell-shaped flowers followed by yellow or orange berries. They have been placed in different species by different authors. They are highly variable perennial herbaceous plants with long thick roots (often branched) and almost no stem. The leaves are borne in a basal rosette, and are variable in size and shape, with a maximum length of . They are usually either elliptical in shape or wider towards the end (obovate), with varying degrees of hairiness. Because mandrakes contain deliriant hallucinogenic tropane alkaloids and the shape of t ...
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Mandrake Root, England, 1501-1700 Wellcome L0058458
A mandrake is the root of a plant, historically derived either from plants of the genus '' Mandragora'' found in the Mediterranean region, or from other species, such as ''Bryonia alba'', the English mandrake, which have similar properties. The plants from which the root is obtained are also called "mandrakes". Mediterranean mandrakes are perennial herbaceous plants with ovate leaves arranged in a rosette, a thick upright root, often branched, and bell-shaped flowers followed by yellow or orange berries. They have been placed in different species by different authors. They are highly variable perennial herbaceous plants with long thick roots (often branched) and almost no stem. The leaves are borne in a basal rosette, and are variable in size and shape, with a maximum length of . They are usually either elliptical in shape or wider towards the end (obovate), with varying degrees of hairiness. Because mandrakes contain deliriant hallucinogenic tropane alkaloids and the shape of t ...
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Mandragora Autumnalis1432
Mandragora may refer to: Biology * Any of the species of the plant genus ''Mandragora'', including ** ''Mandragora autumnalis'', mandrake or autumn mandrake ** ''Mandragora caulescens'', Himalayan mandrake ** ''Mandragora officinarum'', mandrake or Mediterranean mandrake, the type species of the genus ** ''Mandragora turcomanica'', Turkmenian mandrake * ''Bryonia alba'', known as false mandrake and English mandrake Arts and entertainment * ''Mandragora'' (novel), 1991 novel by David McRobbie * ''Mandragora'' (film), 1997 film by Wiktor Grodecki * Mandragora (band), UK psychedelic rock band * Mandragora (publisher), Polish publisher of comics, manga and manhwa * Mandragora Movies, Romanian film production company * La Mandrágora, Chilean Surrealist group * ''Mandragora'', ballet by Karol Szymanowski Other uses * Rolando Mandragora (born 1997), Italian footballer * Mandragora (demon), familiar demons who appear in the figures of little men without beards See also * Ma ...
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Mandragora (genus)
''Mandragora'' is a plant genus belonging to the nightshade family (Solanaceae). Members of the genus are known as mandrakes. Between three and five species are placed in the genus. The one or two species found around the Mediterranean constitute the mandrake of ancient writers such as Dioscorides. Two or three further species are found eastwards into China. All are perennial herbaceous plants, with large tap roots and leaves in the form of a rosette. Individual flowers are bell-shaped, whitish through to violet, and followed by yellow or orange berries. Like many members of the Solanaceae, species of ''Mandragora'' contain highly biologically active alkaloids that make the plants poisonous. Their roots in particular have a long use in traditional medicine. Mandrakes are involved in many myths and superstitions. Description Species of ''Mandragora'' are perennial herbaceous plants. They have large vertical tap roots, sometimes forked. Their stems are short or virtually absent. ...
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Atropine
Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia. The intravenous solution usually begins working within a minute and lasts half an hour to an hour. Large doses may be required to treat some poisonings. Common side effects include a dry mouth, large pupils, urinary retention, constipation, and a fast heart rate. It should generally not be used in people with angle closure glaucoma. While there is no evidence that its use during pregnancy causes birth defects, that has not been well studied. It is likely safe during breastfeeding. It is an antimuscarinic (a type of anticholinergic) that works by inhibiting the parasympathetic nervous system. Atropine occurs n ...
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Deliriant
Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics and dissociatives such as LSD and ketamine, respectively, due to their primary effect of causing delirium, as opposed to the more lucid and less disturbed states produced by other types of hallucinogens.Duncan, D. F., and Gold, R. S. (1982). Drugs and the Whole Person. New York: John Wiley & Sons The term generally refers to anticholinergic drugs, which are substances that inhibit the function of the neurotransmitter acetylcholine. Common examples of deliriants include plants of the genera ''Datura'' and ''Brugmansia'' (both containing scopolamine) as well as higher than recommended dosages of diphenhydramine (Benadryl). A number of plant deliriants such as that of the Solanaceae family, particularly in the Americas have been used by some indigenous cultures to reach delirious and altered states for traditions or rituals, such as rites of passage, divin ...
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Bryonia Alba
''Bryonia alba'' (also known as white bryony or wild hop) is a vigorous vine in the family Cucurbitaceae, found in Europe and Northern Iran. It has a growth habit similar to kudzu, which gives it a highly destructive potential outside its native range as a noxious weed. Other common names include false mandrake, English mandrake, wild vine, and wild hops, wild nep, tamus, ladies' seal, and tetterbury. Description An herbaceous, perennial vine of the cucumber family, white bryony is monoecious but diclinous (separate male and female flowers found on the same plant) with a tuberous yellow root. Greenish-white flowers are across. Long curling tendrils, flowers, and fruit all stem from axils of palmately lobed leaves. The fruit is a berry which blackens as it ripens. Distribution White bryony is native to Europe and Northern Iran. It has also been introduced to the United States, where it is listed as a noxious weed in Washington (U.S. state), Washington, Idaho, and Montana. ...
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Tropane Alkaloid
Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloids such as cocaine and scopolamine are notorious for their psychoactive effects, related usage and cultural associations. Particular tropane alkaloids such as these have pharmacological properties and can act as anticholinergics or stimulants. Classification Anticholinergics Anticholinergic drugs and deliriants: * Atropine, racemate, racemic hyoscyamine, from the deadly nightshade (''Atropa belladonna'') * Hyoscyamine, the ''levo''-isomer of atropine, from henbane (''Hyoscyamus niger''), mandrake (''Mandragora officinarum'') and the sorcerers' tree (''Latua pubiflora''). * Hyoscine hydrobromide, Scopolamine, from henbane and ''Datura'' species (Jimson weed) All three acetylcholine-inhibiting chemicals can also be found in the leave ...
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Narcotic
The term narcotic (, from ancient Greek ναρκῶ ''narkō'', "to make numb") originally referred medically to any psychoactive compound with numbing or paralyzing properties. In the United States, it has since become associated with opiates and opioids, commonly morphine and heroin, as well as derivatives of many of the compounds found within raw opium latex. The primary three are morphine, codeine, and thebaine (while thebaine itself is only very mildly psychoactive, it is a crucial precursor in the vast majority of semi-synthetic opioids, such as oxycodone or hydrocodone). Legally speaking, the term "narcotic" may be imprecisely defined and typically has negative connotations. When used in a legal context in the U.S., a narcotic drug is totally prohibited, such as heroin, or one that is used in violation of legal regulation (in this word sense, equal to any controlled substance or illicit drug). In the medical community, the term is more precisely defined and genera ...
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Anticholinergic
Anticholinergics (anticholinergic agents) are substances that block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system. These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, sweat glands, and many other parts of the body. In broad terms, anticholinergics are divided into two categories in accordance with their specific targets in the central and peripheral nervous system and at the neuromuscular junction: antimuscarinic agents, and antinicotinic agents ( ganglionic blockers, neuromuscular blockers). The term "anticholinergic" is typically used to refer to antimuscarinics which competitively inhibit the binding of ACh to muscarinic acetylcholine receptors; such agen ...
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Asphyxia
Asphyxia or asphyxiation is a condition of deficient supply of oxygen to the body which arises from abnormal breathing. Asphyxia causes generalized hypoxia, which affects primarily the tissues and organs. There are many circumstances that can induce asphyxia, all of which are characterized by the inability of a person to acquire sufficient oxygen through breathing for an extended period of time. Asphyxia can cause coma or death. In 2015, about 9.8 million cases of unintentional suffocation occurred which resulted in 35,600 deaths. The word asphyxia is from Ancient Greek "without" and , "squeeze" (throb of heart). Causes Situations that can cause asphyxia include but are not limited to: airway obstruction, the constriction or obstruction of airways, such as from asthma, laryngospasm, or simple blockage from the presence of foreign materials; from being in environments where oxygen is not readily accessible: such as underwater, in a low oxygen atmosphere, or in a vacuum; envir ...
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Mydriasis
Mydriasis is the dilation of the pupil, usually having a non-physiological cause, or sometimes a physiological pupillary response. Non-physiological causes of mydriasis include disease, trauma, or the use of certain types of drugs. Normally, as part of the pupillary light reflex, the pupil dilates in the dark and constricts in the light to respectively improve vividity at night and to protect the retina from sunlight damage during the day. A ''mydriatic'' pupil will remain excessively large even in a bright environment. The excitation of the radial fibres of the iris which increases the pupillary aperture is referred to as a mydriasis. More generally, mydriasis also refers to the natural dilation of pupils, for instance in low light conditions or under sympathetic stimulation. Fixed, unilateral mydriasis could be a symptom of raised intracranial pressure. The opposite, constriction of the pupil, is referred to as miosis. Both mydriasis and miosis can be physiological. Anisocori ...
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Mandragoras 454 Dodoens 1583
In European folklore, mandragoras are familiar demons who appear in the figures of little men without beards. Mandragoras are thought to be little dolls or figures given to sorcerers by the Devil for the purpose of being consulted by them in time of need; and it would seem as if this conception had sprung directly from that of the '' fetish'', which is nothing else than a dwelling-place made by a shaman or medicine-man for the reception of any wandering spirit who chooses to take up his abode therein. See also * Mandrake * Imp * Golem * Homunculus A homunculus ( , , ; "little person") is a representation of a small human being, originally depicted as small statues made out of clay. Popularized in sixteenth-century alchemy and nineteenth-century fiction, it has historically referred to the ... References Demons {{reli-stub ...
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