|
Mamba
Mambas are fast moving highly venomous snakes of the genus ''Dendroaspis'' (which literally means "tree asp") in the family Elapidae. Four extant species are recognised currently; three of those four species are essentially arboreal and green in colour, whereas the black mamba, ''Dendroaspis polylepis'', is largely terrestrial and generally brown or grey in colour. All are native to various regions in sub-Saharan Africa and all are feared throughout their ranges, especially the black mamba. In Africa there are many legends and stories about mambas. also at/ref> Behaviour The three green species of mambas are arboreal, whereas the black mamba is largely terrestrial. The black mamba is one of the largest and most venomous snakes in Africa. All four species are active diurnal hunters, preying on birds, lizards, and small mammals. At nightfall some species, especially the terrestrial black mamba, shelter in a lair. A mamba may retain the same lair for years. Mambas and cobras ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Black Mamba
The black mamba (''Dendroaspis polylepis'') is a species of highly venomous snake belonging to the family Elapidae. It is native to parts of sub-Saharan Africa. First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed and commonly grow to . Specimens of have been reported. Its skin colour varies from grey to dark brown. Juvenile black mambas tend to be paler than adults and darken with age. The species is both terrestrial (ground-living) and arboreal (tree-living); it inhabits savannah, woodland, rocky slopes and in some regions, dense forest. It is diurnal and is known to prey on birds and small mammals. Over suitable surfaces, it can move at speeds up to for short distances. Adult black mambas have few natural predators. In a threat display, the black mamba usually opens its inky-black mouth, spreads its narrow neck-flap and sometimes hisses. It is capable of striking at c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Black Mamba
The black mamba (''Dendroaspis polylepis'') is a species of highly venomous snake belonging to the family Elapidae. It is native to parts of sub-Saharan Africa. First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed and commonly grow to . Specimens of have been reported. Its skin colour varies from grey to dark brown. Juvenile black mambas tend to be paler than adults and darken with age. The species is both terrestrial (ground-living) and arboreal (tree-living); it inhabits savannah, woodland, rocky slopes and in some regions, dense forest. It is diurnal and is known to prey on birds and small mammals. Over suitable surfaces, it can move at speeds up to for short distances. Adult black mambas have few natural predators. In a threat display, the black mamba usually opens its inky-black mouth, spreads its narrow neck-flap and sometimes hisses. It is capable of striking at c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dendroaspis Polylepis
The black mamba (''Dendroaspis polylepis'') is a species of highly venomous snake belonging to the family Elapidae. It is native to parts of sub-Saharan Africa. First formally described by Albert Günther in 1864, it is the second-longest venomous snake after the king cobra; mature specimens generally exceed and commonly grow to . Specimens of have been reported. Its skin colour varies from grey to dark brown. Juvenile black mambas tend to be paler than adults and darken with age. The species is both terrestrial (ground-living) and arboreal (tree-living); it inhabits savannah, woodland, rocky slopes and in some regions, dense forest. It is diurnal and is known to prey on birds and small mammals. Over suitable surfaces, it can move at speeds up to for short distances. Adult black mambas have few natural predators. In a threat display, the black mamba usually opens its inky-black mouth, spreads its narrow neck-flap and sometimes hisses. It is capable of striking at con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dendroaspis Angusticeps
The eastern green mamba (''Dendroaspis angusticeps'') is a highly venomous snake species of the mamba genus ''Dendroaspis'' native to the coastal regions of southern East Africa. Species description, Described by Scottish people, Scottish surgeon and zoologist Andrew Smith (zoologist), Andrew Smith in 1849, it has a slender build with a bright green back and green-yellow ventral scales. Adult females average around in length, and males are slightly sexual dimorphism, smaller. A shy and elusive species, the eastern green mamba is rarely seen. This elusiveness is usually attributed to its arboreal habitat and green colouration, which acts as camouflage in its natural environment. It has also been observed to use Ambush predator, ambush predation, like many viper, vipers, contrary to the active foraging style typical of other Elapidae, elapid snakes. It preys on birds, egg, eggs, bat, bats, and rodents such as Mouse, mice, rat, rats, and Gerbillinae, gerbils. Its venom consists of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eastern Green Mamba
The eastern green mamba (''Dendroaspis angusticeps'') is a highly venomous snake species of the mamba genus ''Dendroaspis'' native to the coastal regions of southern East Africa. Described by Scottish surgeon and zoologist Andrew Smith in 1849, it has a slender build with a bright green back and green-yellow ventral scales. Adult females average around in length, and males are slightly smaller. A shy and elusive species, the eastern green mamba is rarely seen. This elusiveness is usually attributed to its arboreal habitat and green colouration, which acts as camouflage in its natural environment. It has also been observed to use ambush predation, like many vipers, contrary to the active foraging style typical of other elapid snakes. It preys on birds, eggs, bats, and rodents such as mice, rats, and gerbils. Its venom consists of both neurotoxins and cardiotoxins. Symptoms of envenomation include swelling of the injection site, dizziness, and nausea, accompanied by diff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dendroaspis Viridis
The western green mamba (''Dendroaspis viridis'') is a long, thin, and highly venomous snake species of the mamba genus, ''Dendroaspis''. This species was first described in 1844 by American herpetologist Edward Hallowell. The western green mamba is a fairly large and predominantly arboreal species, capable of navigating through trees swiftly and gracefully. It will also descend to ground level to pursue prey such as rodents and other small mammals. The western green mamba is a shy and agile snake that lives mainly in the coastal tropical rainforest, thicket, and woodland regions of western Africa. Its venom is a highly potent mixture of rapid-acting presynaptic and postsynaptic neurotoxins (dendrotoxins), cardiotoxins and fasciculins. Some consider this species not to be a particularly aggressive snake, but others have suggested that they are extremely nervous and are prone to attack aggressively when cornered. Conflict with humans is low compared to some other species found i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dendroaspis Jamesoni
Jameson's mamba (''Dendroaspis jamesoni'') is a species of highly venomous snake native to equatorial Africa. A member of the mamba genus, ''Dendroaspis'', it is slender with dull green upper parts and cream underparts and generally ranges from in length. Described by Scottish naturalist Thomas Traill in 1843, it has two recognised subspecies: the nominate subspecies from central and west sub-Saharan Africa and the eastern black-tailed subspecies from eastern sub-Saharan Africa, mainly western Kenya. Predominantly arboreal, Jameson's mamba preys mainly on birds and mammals. Its venom consists of both neurotoxins and cardiotoxins. Symptoms of envenomation in humans include pain and swelling at the bite site, followed by swelling, chills, sweating, abdominal pain and vomiting, with subsequent slurred speech, difficulty breathing and paralysis. Fatalities have been recorded within three to four hours of being bitten. The venom of the eastern subspecies is around twice as poten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dendroaspis Polylepis Striking
Mambas are fast moving highly venomous snakes of the genus ''Dendroaspis'' (which literally means "tree asp") in the family Elapidae. Four extant species are recognised currently; three of those four species are essentially arboreal and green in colour, whereas the black mamba, ''Dendroaspis polylepis'', is largely terrestrial and generally brown or grey in colour. All are native to various regions in sub-Saharan Africa and all are feared throughout their ranges, especially the black mamba. In Africa there are many legends and stories about mambas. also at/ref> Behaviour The three green species of mambas are arboreal, whereas the black mamba is largely terrestrial. The black mamba is one of the largest and most venomous snakes in Africa. All four species are active diurnal hunters, preying on birds, lizards, and small mammals. At nightfall some species, especially the terrestrial black mamba, shelter in a lair. A mamba may retain the same lair for years. Mambas and cob ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calciseptine
Calciseptine (CaS) is a natural neurotoxin isolated from the black mamba ''Dendroaspis p. polylepis'' venom. This toxin consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type calcium channels, but not other voltage-dependent Ca2+ channels such as N-type and T-type channels. History The black mamba (''Dendroaspis polylepis'') is generally considered to be one of the deadliest snakes on the planet, and is responsible for many fatalities throughout its sub-Saharan Africa range. Without treatment, the bite of a Black Mamba causes a 100% mortality rate. The venom of the Black Mamba consists of more than 28 peptides. One of these peptides is calciseptine. It makes up 2.8% of the venom of the Black Mamba. When first purified, the peptide was called protein E3, which was later changed to calciseptine by Weille et al. Importance Calciseptine has been shown to specifically inhibit the L-type voltage-gated Ca2+ channels and was the first natura ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elapidae
Elapidae (, commonly known as elapids ; grc, ἔλλοψ ''éllops'' "sea-fish") is a family of snakes characterized by their permanently erect fangs at the front of the mouth. Most elapids are venomous, with the exception of the genus Emydocephalus. Many members of this family exhibit a threat display of rearing upwards while spreading out a neck flap. Elapids are endemic to tropical and subtropical regions around the world, with terrestrial forms in Asia, Australia, Africa, and the Americas and marine forms in the Pacific and Indian Oceans. Members of the family have a wide range of sizes, from the white-lipped snake to the king cobra. Most species have neurotoxic venom which is channeled by their hollow fangs, and some may contain other toxic components in various proportions. The family includes 55 genera with some 360 species and over 170 subspecies. Description Terrestrial elapids look similar to the Colubridae; almost all have long, slender bodies with smooth scal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fasciculin
Fasciculins are a class of toxic proteins found in certain snake venoms, notably some species of mamba. Investigations have revealed distinct forms in some green mamba venoms, in particular FAS1 and FAS2 Fasciculins are so called because they cause intense fasciculation in muscle fascicles of susceptible organisms, such as the preferred prey of the snakes. This effect helps to incapacitate the muscles, either killing the prey, or paralysing it so that the snake can swallow it. Fundamental mechanism of action The mechanism of action of the FAS proteins is associated with their ability to attach to molecules of the acetylcholinesterase in the muscles and their neuromuscular junctions, and thereby interfere with their necessary neuromodulatory inhibition. Molecular nature and physiological effect Fasciculins from mambas inhibit mammalian and fish acetylcholinesterases intensely, but are less active against the corresponding enzymes in insects, reptiles and birds. As one might ex ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calcicludine
Calcicludine (CaC) is a protein toxin from the venom of the green mamba that inhibits high-voltage-activated calcium channels, especially L-type calcium channels. Sources Calcicludine is a toxin in the venom of the green mamba ''(Dendroaspis angusticeps)''. Chemistry Calcicludine is a 60-amino acid polypeptide with six cysteines forming three disulfide bridges. Calcicludine structurally resembles dendrotoxin, but works differently, since even at high concentrations, calcicludine has no effect on dendrotoxin-sensitive potassium channels in chicken and rat neurons. Target Calcicludine is a blocker of high-voltage-activated calcium channels (L-, N- and P-type channels). It has highest affinity to the L-type calcium channel ( IC50 = 88nM . However, sensitivity of the drug on the channel depends on the species and the tissue. For example, the IC50 for block of L-type calcium channels on a cerebellar granule cell is 0.2 nM, but the IC50 of the block of rat peripheral DRG neu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
