Lumbar Ganglia
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Lumbar Ganglia
The lumbar ganglia are paravertebral ganglia located in the inferior portion of the sympathetic trunk. The lumbar portion of the sympathetic trunk typically has 4 lumbar ganglia. The lumbar splanchnic nerves arise from the ganglia here, and contribute sympathetic efferent fibers to the nearby plexuses. The first two lumbar ganglia have both white and gray rami communicates. Function Paravertebral ganglia are divided into cervical, thoracic, lumbar, and sacral ganglia. Each controls different glands and muscle groups since each muscle and gland receives input from postganglionic neurons that originated from different levels of paravertebral ganglia. The lumbar part of the sympathetic trunk contains four interconnected ganglia. Superiorly, it is continuous with thoracic sympathetic ganglion and inferiorly continuous with sacral sympathetic ganglion. Presynaptic neurons traveling from the spinal cord terminate in the paravertebral ganglia (cervical, thoracic, lumbar, sacral) or the ...
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Paravertebral Ganglia
The sympathetic ganglia, or paravertebral ganglia are autonomic ganglia, of the sympathetic nervous system. Ganglia are 20,000 to 30,000 afferent and efferent nerve cell bodies that run along on either side of the spinal cord. Afferent nerve cell bodies bring information from the body to the brain and spinal cord, while efferent nerve cell bodies bring information from the brain and spinal cord to the rest of the body. The cell bodies create long sympathetic chains that are on either side of the spinal cord. They also form para- or pre-vertebral ganglia of gross anatomy. The efferent nerve cell bodies bring information from the brain to the body regarding perceptions of danger. This perception of danger can instigate the fight-or-flight response associated with the sympathetic nervous system. The fight-or-flight response is adaptive when there is a real and present danger which can be avoided or diminished through increased sympathetic activity. Sympathetic activity could be incr ...
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Sympathetic Trunk
The sympathetic trunks (sympathetic chain, gangliated cord) are a paired bundle of nerve fibers that run from the base of the skull to the coccyx. They are a major component of the sympathetic nervous system. Structure The sympathetic trunk lies just lateral to the vertebral bodies for the entire length of the vertebral column. It interacts with the anterior rami of spinal nerves by way of rami communicantes. The sympathetic trunk permits preganglionic fibers of the sympathetic nervous system to ascend to spinal levels superior to T1 and descend to spinal levels inferior to L2/3.Greenstein B., Greenstein A. (2002): Color atlas of neuroscience – Neuroanatomy and neurophysiology. Thieme, Stuttgart – New York, . The superior end of it is continued upward through the carotid canal into the skull, and forms a plexus on the internal carotid artery; the inferior part travels in front of the coccyx, where it converges with the other trunk at a structure known as the ganglion impar. ...
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Lumbar Splanchnic Nerves
The lumbar splanchnic nerves are splanchnic nerves that arise from the lumbar part of the sympathetic trunk and travel to an adjacent plexus near the aorta. They originate from L1 and L2. These nerves contain preganglionic sympathetic and general visceral afferent fibers. The site of synapse is found in the inferior mesenteric ganglion and the postsynaptic fibers innervate the smooth muscle and glands of the pelvic viscera and hindgut The hindgut (or epigaster) is the posterior ( caudal) part of the alimentary canal. In mammals, it includes the distal one third of the transverse colon and the splenic flexure, the descending colon, sigmoid colon and up to the ano-rectal juncti .... External links * Nerves {{neuroanatomy-stub ...
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Ganglion
A ganglion is a group of neuron cell bodies in the peripheral nervous system. In the somatic nervous system this includes dorsal root ganglia and trigeminal ganglia among a few others. In the autonomic nervous system there are both sympathetic and parasympathetic ganglia which contain the cell bodies of postganglionic sympathetic and parasympathetic neurons respectively. A pseudoganglion looks like a ganglion, but only has nerve fibers and has no nerve cell bodies. Structure Ganglia are primarily made up of somata and dendritic structures which are bundled or connected. Ganglia often interconnect with other ganglia to form a complex system of ganglia known as a plexus. Ganglia provide relay points and intermediary connections between different neurological structures in the body, such as the peripheral and central nervous systems. Among vertebrates there are three major groups of ganglia: *Dorsal root ganglia (also known as the spinal ganglia) contain the cell bodies of se ...
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Rami Communicates
Ramus communicans (plural rami communicantes) is the Latin term used for a nerve which connects two other nerves, and can be translated as "communicating branch". Structure When used without further definition, it almost always refers to a communicating branch between a spinal nerve and the sympathetic trunk. More specifically, it usually refers to one of the following : * Gray ramus communicans * White ramus communicans The grey and white rami communicantes are responsible for conveying autonomic signals, specifically for the sympathetic nervous system. Their difference in coloration is caused by differences in myelination of the nerve fibres contained within, i.e. there are more myelinated than unmyelinated fibres in the white rami communicantes while the converse is true for the grey rami communicantes. Gray ramus communicans The grey rami communicantes exist at every level of the spinal cord and are responsible for carrying postganglionic nerve fibres from the paraverte ...
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Paravertebral Ganglia
The sympathetic ganglia, or paravertebral ganglia are autonomic ganglia, of the sympathetic nervous system. Ganglia are 20,000 to 30,000 afferent and efferent nerve cell bodies that run along on either side of the spinal cord. Afferent nerve cell bodies bring information from the body to the brain and spinal cord, while efferent nerve cell bodies bring information from the brain and spinal cord to the rest of the body. The cell bodies create long sympathetic chains that are on either side of the spinal cord. They also form para- or pre-vertebral ganglia of gross anatomy. The efferent nerve cell bodies bring information from the brain to the body regarding perceptions of danger. This perception of danger can instigate the fight-or-flight response associated with the sympathetic nervous system. The fight-or-flight response is adaptive when there is a real and present danger which can be avoided or diminished through increased sympathetic activity. Sympathetic activity could be incr ...
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Presynaptic Neuron
Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body. At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are contained within small sacs called synaptic vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to neurotransmitter receptors on the postsynaptic cell. Finally, the neurotransmitters are cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell or on ...
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Nerve Block
Nerve block or regional nerve blockade is any deliberate interruption of signals traveling along a nerve, often for the purpose of pain relief. Local anesthetic nerve block (sometimes referred to as simply "nerve block") is a short-term block, usually lasting hours or days, involving the injection of an anesthetic, a corticosteroid, and other agents onto or near a nerve. Neurolytic block, the deliberate temporary degeneration of nerve fibers through the application of chemicals, heat, or freezing, produces a block that may persist for weeks, months, or indefinitely. Neurectomy, the cutting through or removal of a nerve or a section of a nerve, usually produces a permanent block. Because neurectomy of a sensory nerve is often followed, months later, by the emergence of new, more intense pain, sensory nerve neurectomy is rarely performed. The concept of nerve block sometimes includes ''central nerve block'', which includes epidural and spinal anaesthesia. Local anesthetic nerve bl ...
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Complex Regional Pain Syndrome
Complex regional pain syndrome (CRPS) is any of several painful conditions that are characterized by a continuing (spontaneous and/or evoked) regional pain that is seemingly disproportionate in time or degree to the usual course of any known trauma or other lesion. Usually starting in a limb, it manifests as extreme pain, swelling, limited range of motion, and changes to the skin and bones. It may initially affect one limb and then spread throughout the body; 35% of affected people report symptoms throughout their whole bodies. Two types exist: reflex sympathetic dystrophy (RSD) and causalgia. Having both types is possible. Classification The classification system in use by the International Association for the Study of Pain (IASP) divides CRPS into two types. It is recognised that people may exhibit both types of CRPS. Signs and symptoms Clinical features of CRPS have been found to be neurogenic inflammation, inflammation resulting from the release of certain proinflammat ...
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Neuropathic
Peripheral neuropathy, often shortened to neuropathy, is a general term describing disease affecting the peripheral nerves, meaning nerves beyond the brain and spinal cord. Damage to peripheral nerves may impair sensation, movement, gland, or organ function depending on which nerves are affected; in other words, neuropathy affecting motor, sensory, or autonomic nerves result in different symptoms. More than one type of nerve may be affected simultaneously. Peripheral neuropathy may be acute (with sudden onset, rapid progress) or chronic (symptoms begin subtly and progress slowly), and may be reversible or permanent. Common causes include systemic diseases (such as diabetes or leprosy), hyperglycemia-induced glycation, vitamin deficiency, medication (e.g., chemotherapy, or commonly prescribed antibiotics including metronidazole and the fluoroquinolone class of antibiotics (such as ciprofloxacin, levofloxacin, moxifloxacin)), traumatic injury, ischemia, radiation therapy, excessiv ...
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