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Jet Injector
A jet injector is a type of medical injecting syringe device used for a method of drug delivery known as jet injection, in which a narrow, high-pressure stream of liquid penetrates the outermost layer of the skin (stratum corneum) to deliver medication to targeted underlying tissues of the epidermis or dermis ("cutaneous" injection, also known as classical "intradermal" injection), fat ("subcutaneous" injection), or muscle ("intramuscular" injection). The jet stream is usually generated by the pressure of a piston in an enclosed liquid-filled chamber. The piston is usually pushed by the release of a compressed metal spring, although investigational devices may use piezoelectric effects and other novel technologies to pressurize the liquid in the chamber. The springs of currently-marketed and historical devices may be compressed by operator muscle power, hydraulic fluid, built-in battery-operated motors, compressed air or gas, and other means. Gas-powered and hydraulically powere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lactate Dehydrogenase Elevating Virus
Lactate dehydrogenase elevating virus (LDV) constitutes the species ''Gamamaarterivirus lacdeh'' which is part of the family ''Arteriviridae'' and order '' Nidovirales''. The order ''Nidovirales'' also includes the family of coronaviruses. Arteriviruses infect macrophages in animals and cause a variety of diseases. LDV specifically causes lifelong persistent viremia in mice, but does not harm the host and only slightly harms the immune system. The main clinical sign is an increased level of the plasma enzyme lactate dehydrogenase (LDH). LDV has a remarkably narrow cell type specificity, meaning nothing homologous with LDV in mice has been found in another species. Discovery LDV was discovered in 1960 by Dr. Vernon Riley and his colleagues while they were working with plasma enzymes in tumor-bearing mice. They found that many types of transplantable tumors caused a five to tenfold increase in the plasma lactate dehydrogenase (LDH) activity within three days of the transplantation. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aaron Ismach
Aaron Ismach (1920 in Brooklyn Brooklyn () is a borough of New York City, coextensive with Kings County, in the U.S. state of New York. Kings County is the most populous county in the State of New York, and the second-most densely populated county in the United States, be ..., New York (state), New York - 2007) was an American scientist and inventor, who made a significative contribution to smallpox eradication by inventing the Subcutaneous injection, subcutaneous jet injector. Biography Born in Brooklyn, he earned a bachelor's degree in chemical engineering from the City College of New York, College of the City of New York in 1943, then a master's degree from the New York University Tandon School of Engineering, Polytechnic Institute of Brooklyn in 1953 and a MEE from the New York University in 1956. In the early 1960, Ismach developed a jet injector with an hydraulic pump operated by a foot pedal, known as the Ped-O-Jet. In 1964, Aaron Ismach invented an intradermal no ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
