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In Natura
''In natura'' (Latin for "in Nature") is a phrase to describe conditions present in a non-laboratory environment, to differentiate it from ''in vivo'' (experiments on live organisms in a lab) and ''ex vivo'' (experiments on cultivated cells isolated from multicellular organisms) conditions. See also *in vitro *in silico *ex vivo *in situ *in utero *in papyro ''In papyro'' (literally, "in/on paper") is a cod Latin term for experiments or studies carried out only on paper, for example, epidemiological studies that do not involve clinical subjects, such as meta-analysis. The term is similar to phrases su ... References {{reflist Latin biological phrases ...
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Latin Language
Latin (, or , ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the Roman Republic it became the dominant language in the Italy (geographical region), Italian region and subsequently throughout the Roman Empire. Even after the Fall of the Western Roman Empire, fall of Western Rome, Latin remained the common language of international communication, science, scholarship and academia in Europe until well into the 18th century, when other regional vernaculars (including its own descendants, the Romance languages) supplanted it in common academic and political usage, and it eventually became a dead language in the modern linguistic definition. Latin is a fusional language, highly inflected language, with three distinct grammatical gender, genders (masculine, feminine, and neuter), six or seven ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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In Silico
In biology and other experimental sciences, an ''in silico'' experiment is one performed on computer or via computer simulation. The phrase is pseudo-Latin for 'in silicon' (correct la, in silicio), referring to silicon in computer chips. It was coined in 1987 as an allusion to the Latin phrases , , and , which are commonly used in biology (especially systems biology). The latter phrases refer, respectively, to experiments done in living organisms, outside living organisms, and where they are found in nature. History The earliest known use of the phrase was by Christopher Langton to describe artificial life, in the announcement of a workshop on that subject at the Center for Nonlinear Studies at the Los Alamos National Laboratory in 1987. The expression ''in silico'' was first used to characterize biological experiments carried out entirely in a computer in 1989, in the workshop "Cellular Automata: Theory and Applications" in Los Alamos, New Mexico, by Pedro Miramontes, a ma ...
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Ex Vivo
''Ex vivo'' (Latin: "out of the living") literally means that which takes place outside an organism. In science, ''ex vivo'' refers to experimentation or measurements done in or on tissue from an organism in an external environment with minimal alteration of natural conditions. Testing the effect of compounds on skin biopsies is an example of ''ex vivo'' research, while isolating the primary cells from that biopsy and creating a 3D cell culture model is an example of ''in vitro'' research. Both use human tissues, but the former is a more complex and translational environment for drug testing. A primary advantage of using ''ex vivo'' tissues is the ability to perform tests or measurements that would otherwise not be possible or ethical in living subjects. Tissues may be experimented on in many ways, including in part (e.g. cardiac contractility models using atrial pectinate muscles) or as whole organs (e.g. isolated perfused heart model). Examples of ''ex vivo'' models include: ...
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In Situ
''In situ'' (; often not italicized in English) is a Latin phrase that translates literally to "on site" or "in position." It can mean "locally", "on site", "on the premises", or "in place" to describe where an event takes place and is used in many different contexts. For example, in fields such as physics, geology, chemistry, or biology, ''in situ'' may describe the way a measurement is taken, that is, in the same place the phenomenon is occurring without isolating it from other systems or altering the original conditions of the test. The opposite of ''in situ'' is ''ex situ''. Aerospace In the aerospace industry, equipment on-board aircraft must be tested ''in situ'', or in place, to confirm everything functions properly as a system. Individually, each piece may work but interference from nearby equipment may create unanticipated problems. Special test equipment is available for this ''in situ'' testing. It can also refer to repairs made to the aircraft structure or flight con ...
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Uterus
The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The uterus is a hormone-responsive sex organ that contains glands in its lining that secrete uterine milk for embryonic nourishment. In the human, the lower end of the uterus, is a narrow part known as the isthmus that connects to the cervix, leading to the vagina. The upper end, the body of the uterus, is connected to the fallopian tubes, at the uterine horns, and the rounded part above the openings to the fallopian tubes is the fundus. The connection of the uterine cavity with a fallopian tube is called the uterotubal junction. The fertilized egg is carried to the uterus along the fallopian tube. It will have divided on its journey to form a blastocyst that will implant itself into the lining of the uterus – the endometrium, where it will ...
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In Papyro
''In papyro'' (literally, "in/on paper") is a cod Latin term for experiments or studies carried out only on paper, for example, epidemiological studies that do not involve clinical subjects, such as meta-analysis. The term is similar to phrases such as ''in vivo'', ''in vitro'', or ''in silico''. Like the latter, ''in papyro'' has no actual Latin meaning and was constructed as an analogue to the more popular and longstanding biological sciences terms (vivo and vitro). ''In papyro'' is mutually exclusive from ''in vitro'' and ''in vivo'', but overlaps with ''in silico'' – that is, a study carried out through computer/abstract simulations can also be considered ''in papyro''. See also *''ex vivo'' *''in situ'' *''in utero'' *''in vitro'' *''in vivo'' *''in silico In biology and other experimental sciences, an ''in silico'' experiment is one performed on computer or via computer simulation. The phrase is pseudo-Latin for 'in silicon' (correct la, in silicio), referring to sil ...
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