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IPrEx
iPrEx (from es, Iniciativa Profilaxis Pre-Exposición, "pre-exposure prophylaxis initiative") was a phase III clinical trial to determine whether the antiretroviral medication emtricitabine/tenofovir (as tenofovir disoproxil fumarate) could safely and effectively prevent HIV acquisition through sex in men who have sex with men and transgender women. iPrEx was the first human study of an HIV prevention strategy known as pre-exposure prophylaxis, or PrEP. The study began in 2007 at four study sites in Peru and Ecuador, following three years of extensive community and stakeholder consultation. In 2008 the study expanded to seven additional sites in Brazil, South Africa, Thailand and the United States. Study sponsors iPrEx was sponsored by the US National Institutes of Health (NIH) through a grant to the Gladstone Institutes, a non-profit independent research organization affiliated to the University of California at San Francisco. Additional support for the conduct of the study w ...
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iPrEx (from es, Iniciativa Profilaxis Pre-Exposición, "pre-exposure prophylaxis initiative") was a phase III clinical trial to determine whether the antiretroviral medication emtricitabine/tenofovir (as tenofovir disoproxil, tenofovir disoproxil fumarate) could safely and effectively prevent HIV acquisition through sex in men who have sex with men and transgender women. iPrEx was the first human study of an HIV prevention strategy known as pre-exposure prophylaxis, or PrEP. The study began in 2007 at four study sites in Peru and Ecuador, following three years of extensive community and stakeholder consultation. In 2008 the study expanded to seven additional sites in Brazil, South Africa, Thailand and the United States. Study sponsors iPrEx was sponsored by the US National Institutes of Health (NIH) through a grant to the Gladstone Institutes, a non-profit independent research organization affiliated to the University of California at San Francisco. Additional support for the co ...
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Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) is the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent, usually a virus. The term typically refers to the use of antiviral drugs as a strategy for the prevention of HIV/AIDS. PrEP is one of a number of HIV prevention strategies for people who are HIV negative but who have a higher risk of acquiring HIV, including sexually active adults at increased risk of contracting HIV, people who engage in intravenous drug use (see drug injection), and serodiscordant sexually active couples. When used as directed, PrEP has been shown to be highly effective, reducing the risk of acquiring HIV by up to 99%. , the World Health Organization (WHO) recommends two drug combinations for the use as PrEP for HIV/AIDS: the combination of tenofovir disoproxil and emtricitabine (Truvada), or the combination of tenofovir disoproxil and lamivudine (Cimduo). In October 2019, the US Food and Drug Admin ...
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Fundación Ecuatoriana Equidad
Fundación Ecuatoriana Equidad was created on October 10, 2000. It is not a federal government program but is a non-profit organization. The organization maintains two main goals. One goal of the organization is to achieve social and political rights for gays, lesbians, bisexuals, transgender people, and people who identify as intersexual. Another goal for the organization is sexual health advocacy. The foundation was started because homosexuals were incarcerated due to a criminalization of sexual activity between people of the same sex by the government. Research Fundación Ecuatoriana Equidad organized local volunteers to participate in the iPrEx study, which was a clinical trial testing the efficacy of a drug used as a pre-exposure prophylaxis against HIV infection. Context Prior to current laws and regulations, Ecuadorians could be arrested for any public displays that went against their common moral value. Men were publicly and brutally attacked for being at gay bars or fo ...
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Gladstone Institutes
Gladstone Institutes is an independent, non-profit biomedical research organization whose focus is to better understand, prevent, treat and cure cardiovascular, viral and neurological conditions such as heart failure, HIV/AIDS and Alzheimer's disease. Its researchers study these diseases using techniques of basic and translational science. Another focus at Gladstone is building on the development of induced pluripotent stem cell technology by one of its investigators, 2012 Nobel Laureate Shinya Yamanaka, to improve drug discovery, personalized medicine and tissue regeneration. Founded in 1979, Gladstone is academically affiliated with the University of California, San Francisco (UCSF), and located adjacent to UCSF's Mission Bay campus. The organization comprises five major institutes, as well as multiple centers focused on various areas of research. The current president of the institute is Deepak Srivastava. History Gladstone Institutes was founded in 1979 as a research and ...
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Asociación Civil Impacta Salud Y Educación
Asociación Civil Impacta Salud y Educación is a non-profit organization which promotes public health in the Andean region of Peru. Established en 2000, Asociación Civil impacta Salud y Educación is a Peruvian non-governmental organization dedicated to clinical, biomedical and public health research as it relates to the health and human development in the fields of HIV/AIDS and other sexually transmitted infections. Conducting investigation and generating knowledge Impacta’s principal activities are the generation of scientific knowledge and the search for the best ways to enhance health conditions at a population level. In this manner, Impacta conducts a range of studies in collaboration with both national and international institutions as well as with the private and public sectors. Prevention research IMPACTA conducts projects that are directed at evaluating HIV prevention interventions as part of international research initiatives such as the HIV Prevention Trials Net ...
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Iquitos
Iquitos (; ) is the capital city of Peru's Maynas Province and Loreto Region. It is the largest metropolis in the Peruvian Amazon, east of the Andes, as well as the ninth-most populous city of Peru. Iquitos is the largest city in the world that cannot be reached by road that isn't on an island, it is accessible only by river and air. It is known as the "capital of the Peruvian Amazon". The city is located in the Great Plains of the Amazon Basin, fed by the Amazon, Nanay, and Itaya rivers. Overall, it constitutes the Iquitos metropolitan area, a conurbation of 471,993 inhabitants consisting of four districts: Iquitos, Punchana, Belén, and San Juan Bautista. The area has long been inhabited by indigenous peoples. According to Spanish historical documents, Iquitos was established around 1757 as a Spanish Jesuit reduction on the banks of the Nanay River. The Jesuits gathered local Napeano (Yameo) and Iquito natives to live here, and they named it ''San Pablo de Napeanos'' ...
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Guayaquil
, motto = Por Guayaquil Independiente en, For Independent Guayaquil , image_map = , map_caption = , pushpin_map = Ecuador#South America , pushpin_relief = 1 , pushpin_map_caption = , pushpin_mapsize = , coordinates = , subdivision_type = Country , subdivision_name = Ecuador , subdivision_type1 = Province , subdivision_name1 = Guayas , subdivision_type2 = Canton , subdivision_name2 = Guayaquil , established_title = Spanish foundation , established_date = , founder = Francisco de Orellana , named_for = Guayas and Quil , established_title2 = Independence , established_date2 = , parts_type = Urban ...
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San Francisco
San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of California cities by population, fourth most populous in California and List of United States cities by population, 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of , at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the County statistics of the United States, fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include ''SF'', ''San Fran'', ''The '', ''Frisco'', and '' ...
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Boston
Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- most populous city in the country. The city boundaries encompass an area of about and a population of 675,647 as of 2020. It is the seat of Suffolk County (although the county government was disbanded on July 1, 1999). The city is the economic and cultural anchor of a substantially larger metropolitan area known as Greater Boston, a metropolitan statistical area (MSA) home to a census-estimated 4.8 million people in 2016 and ranking as the tenth-largest MSA in the country. A broader combined statistical area (CSA), generally corresponding to the commuting area and including Providence, Rhode Island, is home to approximately 8.2 million people, making it the sixth most populous in the United States. Boston is one of the oldest ...
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Fenway Health
Fenway Health (formally Fenway Community Health Center, Inc.) is an LGBT (lesbian, gay, bisexual and transgender) health care, research and advocacy organization founded by Northeastern University students and headquartered in Boston, Massachusetts.''Bay Windows''Hannah Clay Wareham, "Fenway Health: new building, classic message," August 6, 2009 accessed January 18, 2011 History In 1971, Northeastern University students opened a drop-in center in the basement of a building owned by the Christian Science Church. They named the center the Fenway Community Health Center and staffed it with volunteer nursing students. By 1973, demand had grown to the point where Fenway incorporated as a freestanding health center and sought a larger space at 16 Haviland Street. Today, this space serves as Fenway: Sixteen, the home of Fenway's HIV Counseling, Testing & Referrals Program, Health Navigation Services, Helplines, and gay and bisexual men's health programs. The 16 Haviland Street location ha ...
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