Hemispherectomy
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Hemispherectomy
Hemispherectomy is a neurosurgical procedure in which a cerebral hemisphere (half of the upper brain, or cerebrum) is removed or disconnected that is used to treat a variety of refractory or drug-resistant seizure disorders (epilepsy). Refractory or drug-resistant epilepsy is defined as seizures that fail to be controlled using 2 or more appropriate anti-seizure medications. About one in three patients with epilepsy have drug-resistant epilepsy and of those, about half of them have focal epilepsy that can potentially be treated with epilepsy surgery. In drug-resistant epilepsy where all or most seizures arise from one hemisphere, hemispherectomy is a highly effective procedure producing seizure freedom in about 80-90% of patients. In addition to controlling seizures and as a result of that, improved development and cognition is also very frequently achieved after hemispherectomy. Most patients who qualify for hemispherectomy already have neurological deficits such as hemibody weakne ...
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Hemispherectomy Foundation
The Hemispherectomy Foundation is a 501(c)(3) non-profit organization founded to provide a support structure for children, and the families of children who have had or are preparing to have hemispherectomy brain surgery. The foundation also provides scholarships for college, trade schools, and summer camps, as well as financial assistance and other support as needed. It is based in Aledo, Texas. History The Hemispherectomy Foundation was founded in 2008, when a six-year-old girl, Jessie Hall, was hospitalized with Rasmussen's Encephalitis at Johns Hopkins Hospital. Jessie was undergoing hemispherectomy surgery (removal or disconnection of one-half of the brain) to control continuous seizures. Although The Hemispherectomy Foundation is based in the United States of America, it provides support globally. Ben Carson, M.D., director of pediatric neurosurgery, at Johns Hopkins Hospital in Baltimore, Maryland Baltimore ( , locally: or ) is the List of municipalities in Mar ...
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Ben Carson
Benjamin Solomon Carson Sr. (born September 18, 1951) is an American retired neurosurgeon and politician who served as the 17th United States Secretary of Housing and Urban Development from 2017 to 2021. A pioneer in the field of neurosurgery, he was a candidate for President of the United States in the 2016 Republican primaries. Carson became the director of pediatric neurosurgery at the Johns Hopkins Children's Center in 1984 at age 33, then the youngest chief of pediatric neurosurgery in the United States. In 1987, he gained significant fame after leading a team of surgeons in the first known separation of conjoined twins joined at the back of the head. Although surgically a success, the twins continued to experience neurologic/medical complications. His additional accomplishments include performing the first successful neurosurgical procedure on a fetus inside the womb, developing new methods to treat brain-stem tumors, and revitalizing hemispherectomy techniques for controlli ...
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Cerebral Hemisphere
The vertebrate cerebrum (brain) is formed by two cerebral hemispheres that are separated by a groove, the longitudinal fissure. The brain can thus be described as being divided into left and right cerebral hemispheres. Each of these hemispheres has an outer layer of grey matter, the cerebral cortex, that is supported by an inner layer of white matter. In eutherian (placental) mammals, the hemispheres are linked by the corpus callosum, a very large bundle of nerve fibers. Smaller commissures, including the anterior commissure, the posterior commissure and the fornix, also join the hemispheres and these are also present in other vertebrates. These commissures transfer information between the two hemispheres to coordinate localized functions. There are three known poles of the cerebral hemispheres: the ''occipital pole'', the ''frontal pole'', and the ''temporal pole''. The central sulcus is a prominent fissure which separates the parietal lobe from the frontal lobe and the prim ...
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Walter Dandy
Walter Edward Dandy (April 6, 1886 – April 19, 1946) was an American neurosurgeon and scientist. He is considered one of the founding fathers of neurosurgery, along with Victor Horsley (1857–1916) and Harvey Cushing (1869–1939). Dandy is credited with numerous neurosurgical discoveries and innovations, including the description of the circulation of cerebrospinal fluid in the brain, surgical treatment of hydrocephalus, the invention of air ventriculography and pneumoencephalography, the description of brain endoscopy, the establishment of the first intensive care unit ( Fox 1984, p. 82), and the first clipping of an intracranial aneurysm, which marked the birth of cerebrovascular neurosurgery. During his 40-year medical career, Dandy published five books and more than 160 peer-reviewed articles while conducting a full-time, ground-breaking neurosurgical practice in which he performed during his peak years about 1000 operations per year ( Sherman et al. 2006). He was re ...
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Epilepsy
Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical activity in the brain. These episodes can result in physical injuries, either directly such as broken bones or through causing accidents. In epilepsy, seizures tend to recur and may have no immediate underlying cause. Isolated seizures that are provoked by a specific cause such as poisoning are not deemed to represent epilepsy. People with epilepsy may be treated differently in various areas of the world and experience varying degrees of social stigma due to the alarming nature of their symptoms. The underlying mechanism of epileptic seizures is excessive and abnormal neuronal activity in the cortex of the brain which can be observed in the electroencephalogram (EEG) of an individual. The reason this occurs in most cases of epilepsy is u ...
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Neuropsychology
Neuropsychology is a branch of psychology concerned with how a person's cognition and behavior are related to the brain and the rest of the nervous system. Professionals in this branch of psychology often focus on how injuries or illnesses of the brain affect cognitive and behavioral functions. It is both an experimental and clinical field of psychology, thus aiming to understand how behavior and cognition are influenced by brain function and concerned with the medical diagnosis, diagnosis and therapy, treatment of behavioral and cognitive effects of neurological disorders. Whereas classical neurology focuses on the pathology of the nervous system and classical psychology is largely divorced from it, neuropsychology seeks to discover how the brain neural correlates of consciousness, correlates with the mind through the study of neurological patients. It thus shares concepts and concerns with neuropsychiatry and with behavioral neurology in general. The term ''neuropsychology'' h ...
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Corpus Callosotomy
Corpus callosotomy is a palliative surgical procedure for the treatment of medically refractory epilepsy. In this procedure the corpus callosum is cut through in an effort to limit the spread of epileptic activity between the two halves of the brain. After the operation the brain has much more difficulty sending messages between the hemispheres. Although the corpus callosum is the largest white matter tract connecting the hemispheres, some limited interhemispheric communication is still possible via the anterior commissure and posterior commissure. "Efficacy and relatively low permanent morbidity in corpus callosotomy for medically intractable epilepsy have been demonstrated by more than six decades of experience. In addition to seizure reduction, behavior and quality of life may improve." History The first examples of corpus callosotomy were performed in the 1940s by Dr. William P. van Wagenen, who co-founded and served as president of the American Association of Neurologica ...
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Ahad Israfil
Ahad Israfil (August 23, 1972 – October 18, 2019) was a man from Dayton, Ohio, known for his recovery from a gunshot injury that destroyed most of one of his cerebral hemispheres. Injury In 1987, at age 14, Ahad was shot in the head at work when his employer allegedly knocked a firearm to the floor. After a five-hour operation, doctors were amazed when he attempted to speak. The bullet destroyed brain tissue and damaged half of his skull, but the skin of his scalp survived. The void in his skull was filled in with silicone by Dr. James Apesos. Repairs to his scalp allowed the regrowth of hair, giving him a fairly normal appearance. Life post-injury Ahad used a wheelchair and regained most of his faculties and successfully obtained a degree. He appeared on television programs such as ''World of Pain'' (Bravo, UK), and ''Ripley's Believe it or Not''. Ahad died on October 18, 2019, while in a nursing home. See also * Cognitive neuropsychology * HM (patient) * Hemispherectom ...
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Associated Press
The Associated Press (AP) is an American non-profit news agency headquartered in New York City. Founded in 1846, it operates as a cooperative, unincorporated association. It produces news reports that are distributed to its members, U.S. newspapers and broadcasters. The AP has earned 56 Pulitzer Prizes, including 34 for photography, since the award was established in 1917. It is also known for publishing the widely used '' AP Stylebook''. By 2016, news collected by the AP was published and republished by more than 1,300 newspapers and broadcasters, English, Spanish, and Arabic. The AP operates 248 news bureaus in 99 countries. It also operates the AP Radio Network, which provides newscasts twice hourly for broadcast and satellite radio and television stations. Many newspapers and broadcasters outside the United States are AP subscribers, paying a fee to use AP material without being contributing members of the cooperative. As part of their cooperative agreement with the AP, most ...
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Cognitive Function
Cognitive skills, also called cognitive functions, cognitive abilities or cognitive capacities, are brain-based skills which are needed in acquisition of knowledge, manipulation of information and reasoning. They have more to do with the mechanisms of how people learn, remember, solve problems and pay attention, rather than with actual knowledge. Cognitive skills or functions encompass the domains of perception, attention, memory, learning, decision making, and language abilities. Specialisation of functions Cognitive science has provided theories of how the brain works, and these have been of great interest to researchers who work in the empirical fields of brain science. A fundamental question is whether cognitive functions, for example visual processing and language, are autonomous modules, or to what extent the functions depend on each other. Research evidence points towards a middle position, and it is now generally accepted that there is ''a degree'' of modularity in aspect ...
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Brain
A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons. These neurons typically communicate with one another by means of long fibers called axons, which carry trains of signal pulses called action potentials to distant parts of the brain or body targeting specific recipient cells. Physiologically, brains exert centralized control over a body's other organs. They act on the rest of the body both by generating patterns of muscle activity and by driving the secretion of chemicals called hormones. This centralized control allows rapid and coordinated respon ...
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Humor
Humour (English in the Commonwealth of Nations, Commonwealth English) or humor (American English) is the tendency of experiences to provoke laughter and provide amusement. The term derives from the humorism, humoral medicine of the ancient Greeks, which taught that the balance of fluids in the human body, known as humours (Latin: ', "body fluid"), controlled human health and emotion. People of all ages and cultures respond to humour. Most people are able to experience humour—be amused, smile or laugh at something funny (such as a pun or joke)—and thus are considered to have a ''sense of humour''. The hypothetical person lacking a sense of humour would likely find the behaviour to be inexplicable, strange, or even irrational. Though ultimately decided by personal taste (aesthetics), taste, the extent to which a person finds something humorous depends on a host of variables, including geographical location, culture, Maturity (psychological), maturity, level of education, inte ...
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