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Hard Flaccid Syndrome
Hard flaccid syndrome (HFS), also known as hard flaccid (HF), is a chronic painful condition characterized by a semi-rigid penis at the flaccid state, a soft Glans penis, glans at the erect state, pelvic pain, low libido, erectile dysfunction, erectile pain, pain on ejaculation, penile sensory changes (numbness or coldness), lower urinary tract symptoms, contraction of the pelvic floor muscles, and psychological distress. Other complaints include Rectum, rectal and Perineum, perineal discomfort, cold hands and feet, and a hollow or detached feeling inside the penile shaft. The majority of HFS patients are in their 20s–30s and symptoms significantly affect one's quality of life. Sufferers typically report the onset of symptoms after trauma due to a mishap during sexual intercourse or tough masturbation, specifically a traumatic injury at the base of the erect penis, possibly affecting the dorsal artery of the penis, the Bulbourethral artery, bulbourethral and the pudendal arteries ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Penis
A penis (plural ''penises'' or ''penes'' () is the primary sexual organ that male animals use to inseminate females (or hermaphrodites) during copulation. Such organs occur in many animals, both vertebrate and invertebrate, but males do not bear a penis in every animal species, and in those species in which the male does bear a so-called penis, the penises in the various species are not necessarily homologous. The term ''penis'' applies to many intromittent organs, but not to all. As an example, the intromittent organ of most cephalopoda is the hectocotylus, a specialized arm, and male spiders use their pedipalps. Even within the Vertebrata there are morphological variants with specific terminology, such as Hemipenis, hemipenes. In most species of animals in which there is an organ that might reasonably be described as a penis, it has no major function other than intromission, or at least conveying the sperm to the female, but in the Eutheria, placental mammals the peni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chronic Prostatitis/chronic Pelvic Pain Syndrome
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), previously known as chronic nonbacterial prostatitis, is long-term pelvic pain and lower urinary tract symptoms (LUTS) without evidence of a bacterial infection. It affects about 2–6% of men. Together with IC/BPS, it makes up urologic chronic pelvic pain syndrome (UCPPS). The cause is unknown. Diagnosis involves ruling out other potential causes of the symptoms such as bacterial prostatitis, benign prostatic hypertrophy, overactive bladder, and cancer. Recommended treatments include multimodal therapy, physiotherapy, and a trial of alpha blocker medication or antibiotics in certain newly diagnosed cases. Some evidence supports some non medication based treatments. Signs and symptoms Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is characterized by pelvic or perineal pain without evidence of urinary tract infection, lasting longer than 3 months, as the key symptom. Symptoms may wax and wane. Pain can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biofeedback
Biofeedback is the process of gaining greater awareness of many physiology, physiological functions of one's own body by using Electronics, electronic or other instruments, and with a goal of being able to Manipulation (psychology), manipulate the body's systems at will. Humans conduct biofeedback naturally all the time, at varied levels of consciousness and intentionality. Biofeedback and the biofeedback loop can also be thought of as Emotional self-regulation, self-regulation. Some of the processes that can be controlled include Electroencephalography, brainwaves, muscle tone, skin conductance, heart rate and pain perception. Biofeedback may be used to improve health, performance, and the physiological changes that often occur in conjunction with changes to thoughts, emotions, and behavior. Recently, technologies have provided assistance with intentional biofeedback. Eventually, these changes may be maintained without the use of extra equipment, for no equipment is necessaril ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurogenic Inflammation
Neurogenic inflammation is inflammation arising from the local release by afferent neurons of inflammatory mediators such as Substance P, Calcitonin Gene-Related Peptide (CGRP), neurokinin A (NKA), and endothelin-3 (ET-3). In such neurons, release of these pro-inflammatory mediators is thought to be triggered by the activation of ion channels that are the principal detectors of noxious environmental stimuli. In particular, the heat/capsaicin receptor TRPV1 and the irritant/wasabi receptor TRPA1. TRPA1 channels stimulated by lipopolysaccharide (LPS) may also cause acute neurogenic inflammation. Once released, these neuropeptides induce the release of histamine from adjacent mast cells. In turn, histamine evokes the release of substance P and calcitonin gene-related peptide; thus, a bidirectional link between histamine and neuropeptides in neurogenic inflammation is established. Neurogenic inflammation appears to play an important role in the pathogenesis of numerous diseases includ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myoneuropathy
Interstitial cystitis (IC), a type of bladder pain syndrome (BPS), is chronic pain in the bladder and pelvic floor of unknown cause. It is the urologic chronic pelvic pain syndrome of women. Symptoms include feeling the need to urinate right away, needing to urinate often, and pain with sex. IC/BPS is associated with depression and lower quality of life. Many of those affected also have irritable bowel syndrome and fibromyalgia. The cause of interstitial cystitis is unknown. While it can, it does not typically run in a family. The diagnosis is usually based on the symptoms after ruling out other conditions. Typically the urine culture is negative. Ulceration or inflammation may be seen on cystoscopy. Other conditions which can produce similar symptoms include overactive bladder, urinary tract infection (UTI), sexually transmitted infections, prostatitis, endometriosis in females, and bladder cancer. There is no cure for interstitial cystitis and management of this condition ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deep Dorsal Vein Of Penis
In human anatomy, the dorsal veins of the penis comprise the superficial dorsal vein of the penis and the deep dorsal vein of the penis. Superficial dorsal vein The ''superficial dorsal vein of the penis'' drains the prepuce and skin of the penis, and, running backward in the subcutaneous tissue, inclines to the right or left, and opens into the corresponding superficial external pudendal vein, a tributary of the great saphenous vein. In contrast to the deep dorsal vein, it lies ''outside'' Buck's fascia. It is possible for the vein to rupture, which presents in a manner similar to penile fracture. Deep dorsal vein The ''deep dorsal vein of the penis'' lies beneath the deep fascia of the penis; it receives the blood from the glans penis and corpora cavernosa penis and courses backward in the middle line between the dorsal arteries; near the root of the penis it passes between the two parts of the suspensory ligament and then through an aperture between the arcuate pubic liga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Levator Ani
The levator ani is a broad, thin muscle group, situated on either side of the pelvis. It is formed from three muscle components: the pubococcygeus, the iliococcygeus, and the puborectalis. It is attached to the inner surface of each side of the lesser pelvis, and these unite to form the greater part of the pelvic floor. The coccygeus muscle completes the pelvic floor, which is also called the ''pelvic diaphragm''. It supports the viscera in the pelvic cavity, and surrounds the various structures that pass through it. The levator ani is the main pelvic floor muscle and painfully contracts during vaginismus. It also contracts rhythmically during orgasm. Structure The levator ani is made up of 3 parts: * Iliococcygeus muscle * Pubococcygeus muscle * Puborectalis muscle The iliococcygeus arises from the inner side of the ischium (the lower and back part of the hip bone) and from the posterior part of the tendinous arch of the obturator fascia, and is attached to the coccyx and a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ischiocavernosus Muscle
The ischiocavernosus muscle (erectores penis ''or'' erector clitoridis in older texts) is a muscle just below the surface of the perineum, present in both men and women. Structure It arises by tendinous and fleshy fibers from the inner surface of the tuberosity of the ischium, behind the crus penis; and from the inferior pubic rami and ischium on either side of the crus. From these points fleshy fibers succeed, and end in an aponeurosis which is inserted into the sides and under surface of the crus penis. Function In females, the ischiocavernosus muscle assists with clitoral erection. In males, it helps to stabilize the erect penis by compressing the crus penis For their anterior three-fourths the corpora cavernosa penis lie in intimate apposition with one another, but behind they diverge in the form of two tapering processes, known as the crura, which are firmly connected to the ischial rami. Traced ... and retarding the return of blood through the veins. Additional imag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bulbospongiosus Muscle
The bulbospongiosus muscle (bulbocavernosus in older texts) is one of the superficial muscles of the perineum. It has a slightly different origin, insertion and function in males and females. In males, it covers the bulb of the penis. In females, it covers the vestibular bulb. In both sexes, it is innervated by the deep or muscular branch of the perineal nerve, which is a branch of the pudendal nerve. Structure In males, the bulbospongiosus is located in the middle line of the perineum, in front of the anus. It consists of two symmetrical parts, united along the median line by a tendinous perineal raphe. It arises from the central tendinous point of the perineum and from the median perineal raphe in front. In females, there is no union, nor a tendinous perineal raphe; the parts are disjoint primarily and arise from the same central tendinous point of the perineum, which is the tendon that is formed at the point where the bulbospongiosus muscle, superficial transverse perinea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortisol
Cortisol is a steroid hormone, in the glucocorticoid class of hormones. When used as a medication, it is known as hydrocortisone. It is produced in many animals, mainly by the ''zona fasciculata'' of the adrenal cortex in the adrenal gland. It is produced in other tissues in lower quantities. It is released with a diurnal cycle and its release is increased in response to stress and low blood-glucose concentration. It functions to increase blood sugar through gluconeogenesis, to suppress the immune system, and to aid in the metabolism of fat, protein, and carbohydrates. It also decreases bone formation. Many of these functions are carried out by cortisol binding to glucocorticoid or mineralocorticoid receptors inside the cell, which then bind to DNA to impact gene expression. Health effects Metabolic response Metabolism of glucose In general, cortisol stimulates gluconeogenesis (the synthesis of 'new' glucose from non-carbohydrate sources, which occurs mainly in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noradrenaline
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as both a hormone and neurotransmitter. The name "noradrenaline" (from Latin '' ad'', "near", and '' ren'', "kidney") is more commonly used in the United Kingdom, whereas "norepinephrine" (from Ancient Greek ἐπῐ́ (''epí''), "upon", and νεφρός (''nephrós''), "kidney") is usually preferred in the United States. "Norepinephrine" is also the international nonproprietary name given to the drug. Regardless of which name is used for the substance itself, parts of the body that produce or are affected by it are referred to as noradrenergic. The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in the so-called fight-or-flight response. In the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenaline
Adrenaline, also known as epinephrine, is a hormone and medication which is involved in regulating visceral functions (e.g., respiration). It appears as a white microcrystalline granule. Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. It plays an essential role in the fight-or-flight response by increasing blood flow to muscles, heart output by acting on the SA node, pupil dilation response, and blood sugar level. It does this by binding to alpha and beta receptors. It is found in many animals, including humans, and some single-celled organisms. It has also been isolated from the plant ''Scoparia dulcis'' found in Northern Vietnam. Medical uses As a medication, it is used to treat several conditions, including allergic reaction anaphylaxis, cardiac arrest, and superficial bleeding. Inhaled adrenaline may be used to improve the symptoms of croup. It may also be used for asthma when other treatments are not eff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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