Homoorientin
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Homoorientin
Isoorientin (or homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-C-glucoside. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic component in ''Gentiana olivieri''. Studies also showed that isoorientin is a potential neuroprotective compound against Alzheimer's disease. Natural occurrences Isoorientin can be isolated from the passion flower, ''Vitex negundo'', ''Terminalia myriocarpa'', the Açaí palm and '' Swertia japonica''. Metabolism * Isoorientin 3'-O-methyltransferase See also * Orientin, the 8-C glucoside of luteolin Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the fir .... References Flavone glucosides C-glycoside natural phenols {{aromatic-stub ...
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Açaí Palm
The açaí palm (, , from Nheengatu ''asai''), ''Euterpe oleracea,'' is a species of palm tree (Arecaceae) cultivated for its fruit (açaí berries, or simply açaí), hearts of palm (a vegetable), leaves, and trunk wood. Global demand for the fruit has expanded rapidly in the 21st century, and the tree is cultivated for that purpose primarily. The species is native to eastern Amazonia, especially in Brazil, mainly in swamps and floodplains. Açaí palms are tall, slender trees growing to more than tall, with pinnate leaves up to long. The fruit is small, round, and black-purple in color. The fruit became a staple food in floodplain areas around the 18th century, but its consumption in urban areas and promotion as a health food only began in the mid 1990s along with the popularization of other Amazonian fruits outside the region. Name The common name comes from the Portuguese adaptation of the Tupian word ', meaning "ruit thatcries or expels water". The importance of the fru ...
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Orientin
Orientin is a flavone, a chemical flavonoid-like compound. It is the 8-C glucoside of luteolin. Natural occurrences Orientin is found in ''Adonis vernalis'', in ''Anadenanthera colubrina'' and ''Anadenanthera peregrina'', and in the ''Phyllostachys nigra'' bamboo leaves ; In food Orientin is also reported in the passion flower, the Açaí palm, buckwheat sprouts, and in millets. Identification in Natural Plants The identification of orientin has been reported widely. Its identification using mass spectrometry is established Welch, C., Zhen, J., Bassène, E., Raskin, I., Simon, J.E. and Wu, Q., 2017. Bioactive polyphenols in kinkéliba tea (Combretum micranthum) and their glucose-lowering activities. Journal of Food and Drug Analysis. See also Isoorientin Isoorientin (or homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-C-glucoside. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic comp ...
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Passion Flower
''Passiflora'', known also as the passion flowers or passion vines, is a genus of about 550 species of flowering plants, the type genus of the family Passifloraceae. They are mostly tendril-bearing vines, with some being shrubs or trees. They can be woody or herbaceous. Passion flowers produce regular and usually showy flowers with a distinctive corona. There can be as many as eight coronal series, as in the case of ''P. xiikzodz''. The flower is pentamerous and ripens into an indehiscent fruit with numerous seeds. List of species Distribution ''Passiflora'' has a largely neotropic distribution, unlike other genera in the family Passifloraceae, which includes more Old World species (such as the genus ''Adenia''). The vast majority of ''Passiflora'' are found in Mexico, Central America, the United States and South America, although there are additional representatives in Southeast Asia and Oceania. New species continue to be identified: for example, '' P. xishuangbannaensis ...
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Luteolin
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul. The luteolin empirical formula was determined by the Austrian chemists Heinrich Hlasiwetz and Leopold Pfaundler in 1864. In 1896, the English chemist Arthur George Perkin proposed the correct structure for luteolin. Perkin's proposed structure for luteolin was confirmed in 1900 when the Polish-Swiss chemist Stanislaw Kostanecki (1860–1910) and his students A. Różycki and J. Tambor synthesized luteolin. Natural occurrences Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen. It has also been isolated from the aromatic flowering plant, ''Salvia t ...
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Luteolin
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul. The luteolin empirical formula was determined by the Austrian chemists Heinrich Hlasiwetz and Leopold Pfaundler in 1864. In 1896, the English chemist Arthur George Perkin proposed the correct structure for luteolin. Perkin's proposed structure for luteolin was confirmed in 1900 when the Polish-Swiss chemist Stanislaw Kostanecki (1860–1910) and his students A. Różycki and J. Tambor synthesized luteolin. Natural occurrences Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen. It has also been isolated from the aromatic flowering plant, ''Salvia t ...
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Glucoside
A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. The name was originally given to plant products of this nature, in which the other part of the molecule was, in the greater number of cases, an aromatic aldehydic or phenolic compound (exceptions are Jinigrin and Jalapin or Scammonin). It has now been extended to include synthetic ethers, such as those obtained by acting on alcoholic glucose solutions with hydrochloric acid, and also the polysaccharoses, e.g. cane sugar, which appear to be ethers also. Although glucose is the most common sugar present in glucosides, many are known which yield rhamnose or iso-dulcite; these may be termed pentosides. Much attention has been given to the non-sugar parts (aglyca) of the molecules; the constitutions of many have been determined, and the compounds synthesi ...
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Isoorientin 3'-O-methyltransferase
In enzymology, an isoorientin 3'-O-methyltransferase () is an enzyme that catalyzes the chemical reaction :S-adenosyl-L-methionine + isoorientin \rightleftharpoons S-adenosyl-L-homocysteine + isoscoparin Thus, the two substrates of this enzyme are S-adenosyl methionine and isoorientin, whereas its two products are S-adenosylhomocysteine and isoscoparin. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase. This enzyme is also called isoorientin 3'-methyltransferase. References * EC 2.1.1 Enzymes of unknown structure O-methylated flavones metaboli ...
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Swertia Japonica
''Swertia'' is a genus in the gentian family containing plants sometimes referred to as the felworts. Some species bear very showy purple and blue flowers. Many members of this genus have medicinal and cultural purposes. Plants of genus ''Frasera'' are sometimes considered part of this genus, sometimes as a separate genus, and sometimes as synonymous. Selected species Species in the genus ''Swertia'' include, but are not limited to: * '' Swertia angustifolia'' Buch.-Ham. ''ex'' D. Don * ''Swertia bimaculata'' (Siebold & Zucc.) C. B. Clarke ** ''Swertia bimaculata'' (Siebold & Zucc.) Hook. f. & Thoms. * '' Swertia calcicola'' Kerr. * '' Swertia chinensis'' (Griseb.) Franch. ** '' Swertia diluta'' (Turcz.) Benth. & Hook. f. * ''Swertia chirayita'' (Roxb. ''ex'' Fleming) H. Karst. ** ''Swertia chirata'' (Wall.) C. B. Clarke * '' Swertia ciliata'' (D. Don ''ex'' G. Don) B. L. Burtt. * '' Swertia cordata'' (Wall. ''ex'' G. Don) C.B. Clarke * '' Swertia dilatata'' C. B. Clarke * '' Sw ...
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Vitex Negundo
''Vitex negundo'', commonly known as the Chinese chaste tree, five-leaved chaste tree, or horseshoe vitex, or nisinda is a large aromatic shrub with quadrangular, densely whitish, tomentose branchlets. It is widely used in folk medicine, particularly in South and Southeast Asia. ''Vitex negundo'' is an erect shrub or small tree growing from in height. The bark is reddish brown. Its leaves are digitate, with five lanceolate leaflets, sometimes three. Each leaflet is around in length, with the central leaflet being the largest and possessing a stalk. The leaf edges are toothed or serrated and the bottom surface is covered in hair. The numerous flowers are borne in panicles in length. Each is around long and are white to blue in color. The petals are of different lengths, with the middle lower lobe being the longest. Both the corolla and calyx are covered in dense hairs. The fruit is a succulent drupe, in diameter, rounded to egg-shaped. It is black or purple when ripe. ...
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Terminalia Myriocarpa
''Terminalia myriocarpa'', the East Indian almond, is a tree species in the genus ''Terminalia'' found in Southeast Asia. Ecology The larvae of the moth '' Acrocercops terminaliae'' feed on ''T. myriocarpa''. Chemistry The phenolic compounds methyl (S)-flavogallonate, gallic acid, methyl gallate, ethyl gallate, 2,3-di-O- S)-4,5,6,4′,5′,6′-hexahydroxybiphenyl-2,2′-diyldicarbonyl(α/β)-D-glucopyranose, vitexin, isovitexin, orientin, iso-orientin, kaempferol 3-O-β-D-rutinoside, rutin, neosaponarin, ellagic acid, flavogallonic acid and (α/β)-punicalagin Punicalagin is an ellagitannin, a type of phenolic compound. It is found as alpha and beta isomers in pomegranates (''Punica granatum''), ''Terminalia catappa'', ''Terminalia myriocarpa'', and in ''Combretum molle'', the velvet bushwillow, a plant ... can be isolated from the leaves of ''T. myriocarpa''.Pharmacologically Active Ellagitannins from Terminalia myriocarpa. Mohamed S.A. Marzouk, Sayed A.A. El-Toumy, Fatma ...
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Flavone
Flavone is an organic compound with the formula . A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products. Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone. Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bo .... References {{Flavones ...
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term memory, remembering recent events. As the disease advances, symptoms can include primary progressive aphasia, problems with language, Orientation (mental), disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and challenging behaviour, behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an alle ...
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