High Altitude Cerebral Edema
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High Altitude Cerebral Edema
High-altitude cerebral edema (HACE) is a medical condition in which the brain swells with fluid because of the physiological effects of traveling to a high altitude. It generally appears in patients who have acute mountain sickness and involves disorientation, lethargy, and nausea among other symptoms. It occurs when the body fails to acclimatize while ascending to a high altitude. It appears to be a vasogenic edema (fluid penetration of the blood–brain barrier), although cytotoxic edema (cellular retention of fluids) may play a role as well. Individuals with the condition must immediately descend to a lower altitude or coma and death can occur. Patients are usually given supplemental oxygen and dexamethasone as well. HACE can be prevented by ascending to heights slowly to allow the body more time to acclimatize. Acetazolamide also helps prevent the condition. Untreated patients usually die within 48 hours. Those who receive treatment may take weeks to fully recover. It is a rar ...
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Concise Oxford English Dictionary
The ''Concise Oxford English Dictionary'' (officially titled ''The Concise Oxford Dictionary'' until 2002, and widely abbreviated ''COD'' or ''COED'') is probably the best-known of the 'smaller' Oxford dictionaries. The latest edition contains over 240,000 entries and 1,728 pages ("concise" compared to the ''OED'' at over 21,000 pages). Its 12th edition, published in 2011, is used by both the United Nations (UN) and NATO as the current authority for spellings in documents in English for international use. It is available as an e-book for a variety of handheld device platforms. In addition to providing information for general use, it documents local variations such as United States and United Kingdom usage. It was started as a derivative of the ''Oxford English Dictionary'' (''OED''), although section S–Z had to be written before the ''Oxford English Dictionary'' reached that stage. However, starting from the 10th edition, it is based on the '' Oxford Dictionary of English'' ( ...
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