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Gout Suppressants
Gout suppressants are agents which control and prevent gout Flare-up, attacks after the first episode. They can be generally classified into two groups by their purpose: drugs used for induction therapy (a therapy used to induce Remission (medicine), remission during the acute attack of a disease) and that for maintenance therapy. Drugs for induction therapy are used during acute gout flare-up to relieve gout symptoms at the acute setting. Standard agents involve Nonsteroidal anti-inflammatory drug, non-steroidal anti-inflammatory drugs (NSAIDs), colchicine and glucocorticoids. On the other hand, drugs for maintenance therapy are used during remission to prevent future flare-ups in long term. They include uricostatic agents, in particular allopurinol and Febuxostat, and Uricosuric, uricosuric agents, such as probenecid and benzbromarone. Drugs for induction therapy Induction therapy of gout targets to relieve acute pain and inflammation during the flare-up. Nonsteroidal anti-in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gout2010
Gout ( ) is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot and Joint effusion, swollen joint, caused by deposition of monosodium urate monohydrate crystals. Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. The Metatarsophalangeal articulations, joint at the base of the big toe is affected in about half of cases. It may also result in Tophus, tophi, kidney stones, or Urate nephropathy, kidney damage. Gout is due to persistently elevated levels of uric acid in the blood. This occurs from a combination of diet, other health problems, and genetic factors. At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout. Gout occurs more commonly in those who: regularly drink beer or sugar-sweetened beverages; eat foods that are high in purines such as liver, shellfish, or anchovies; or are overweight. Diagnosis of gout may be confi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
