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Galactomannan
Galactomannans are polysaccharides consisting of a mannose backbone with galactose side groups, more specifically, a (1-4)-linked beta-D-mannopyranose backbone with branchpoints from their 6-positions linked to alpha-D-galactose, (i.e. 1-6-linked alpha-D-galactopyranose). In order of increasing number of mannose-to-galactose ratio: *fenugreek, fenugreek gum, mannose:galactose ~1:1 *guar gum, mannose:galactose ~2:1 *tara gum, mannose:galactose ~3:1 *locust bean gum or ''carob gum'', mannose:galactose ~4:1 *cassia gum, mannose:galactose ~5:1 Galactomannans are often used in food products to increase the viscosity of the water phase. Guar gum has been used to add viscosity to artificial tears, but is not as stable as Carboxymethyl cellulose, carboxymethylcellulose. Food use Galactomannans are used in foods as stabilizer (chemistry), stabilisers. Guar and locust bean gum (LBG) are commonly used in ice cream to improve texture and reduce ice cream meltdown. LBG is also used extensiv ...
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Galactomannan
Galactomannans are polysaccharides consisting of a mannose backbone with galactose side groups, more specifically, a (1-4)-linked beta-D-mannopyranose backbone with branchpoints from their 6-positions linked to alpha-D-galactose, (i.e. 1-6-linked alpha-D-galactopyranose). In order of increasing number of mannose-to-galactose ratio: *fenugreek, fenugreek gum, mannose:galactose ~1:1 *guar gum, mannose:galactose ~2:1 *tara gum, mannose:galactose ~3:1 *locust bean gum or ''carob gum'', mannose:galactose ~4:1 *cassia gum, mannose:galactose ~5:1 Galactomannans are often used in food products to increase the viscosity of the water phase. Guar gum has been used to add viscosity to artificial tears, but is not as stable as Carboxymethyl cellulose, carboxymethylcellulose. Food use Galactomannans are used in foods as stabilizer (chemistry), stabilisers. Guar and locust bean gum (LBG) are commonly used in ice cream to improve texture and reduce ice cream meltdown. LBG is also used extensiv ...
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Cassia Gum
Cassia gum is the flour and food additives made from the endosperms of the seeds of ''Senna obtusifolia'' and ''Senna tora'' (also called '' Cassia obtusifolia'' or ''Cassia tora''). It is composed of at least 75% polysaccharide, primarily galactomannan with a mannose:galactose ratio of 5:1, resulting in a high molecular mass of 200,000-300,000 Da. Approval Japan In 1995, cassia gum was added to the list of approved food additives in Japan by the Japanese Ministry of Health and Welfare. United States Two GRAS notices were filed to the U.S. Food and Drug Administration (FDA), one on June 23, 2000 (GRN 51) and one on November 21, 2003 (GRN 139), both of which were not evaluated due to notifier's request to cease evaluation. In June 2008, specialty firm Lubrizol Advanced Material filed a petition to the FDA proposing that food regulations be amended to provide for the use of cassia gum as a stabilizer in frozen dairy desserts. Approval in the US is still pending, with no clear indic ...
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Stabilizer (chemistry)
In industrial chemistry, a stabilizer or stabiliser is a chemical that is used to prevent degradation. File:BigPhosphite31570-04-4.png, Tris(2,4-di-tert-butylphenyl)phosphite is a widely used stabilizer in polymers. File:HALSgeneric.png, Partial structure of typical hindered amine light stabilizers, widely used to protect automotive paints from degradation by UV-light. File:Salpn.png, Salpn is a typical metal deactivator used as a fuel additive to suppress oxidation processes that lead to gums and solids. Metal deactivators like salpn form stable complexes with the metals, suppressing their catalytic activity. Overview Heat and light stabilizers are added to plastics because they ensure safe processing and protect products against aging and weathering. The trend is towards fluid systems, pellets, and increased use of masterbatches. There are monofunctional, bifunctional, and polyfunctional stabilizers. In economic terms the most important product groups on the market for stabili ...
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Carbohydrates
In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or may not be different from ''n''), which does not mean the H has covalent bonds with O (for example with , H has a covalent bond with C but not with O). However, not all carbohydrates conform to this precise stoichiometric definition (e.g., uronic acids, deoxy-sugars such as fucose), nor are all chemicals that do conform to this definition automatically classified as carbohydrates (e.g. formaldehyde and acetic acid). The term is most common in biochemistry, where it is a synonym of saccharide (), a group that includes sugars, starch, and cellulose. The saccharides are divided into four chemical groups: monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Monosaccharides and disaccharides, the smallest (lower molecular weight) ...
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Polysaccharides
Polysaccharides (), or polycarbohydrates, are the most abundant carbohydrates found in food. They are long chain polymeric carbohydrates composed of monosaccharide units bound together by glycosidic linkages. This carbohydrate can react with water (hydrolysis) using amylase enzymes as catalyst, which produces constituent sugars (monosaccharides, or oligosaccharides). They range in structure from linear to highly branched. Examples include storage polysaccharides such as starch, glycogen and galactogen and structural polysaccharides such as cellulose and chitin. Polysaccharides are often quite heterogeneous, containing slight modifications of the repeating unit. Depending on the structure, these macromolecules can have distinct properties from their monosaccharide building blocks. They may be amorphous or even insoluble in water. When all the monosaccharides in a polysaccharide are the same type, the polysaccharide is called a homopolysaccharide or homoglycan, but when more t ...
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Edible Thickening Agents
An edible item is any item that is safe for humans to eat. "Edible" is differentiated from "eatable" because it does not indicate how an item tastes, only whether it is fit to be eaten. Nonpoisonous items found in nature – such as some mushrooms, insects, seaweed, and so forth – are referred to as edible. Processed items that normally are not ingested but are specially manufactured to be so, like edible underwear or edible packaging, are also labeled as edible. Edible items in nature It is estimated that approximately half of about 400,000 plant species on earth are edible, yet ''Homo sapiens'' consume only about 200 plant species, because these are the simplest to domesticate. Edible plants found in nature include certain types of mushrooms, flowers, seeds, berries, seaweed, and cacti. Being able to identify the versions of these plants that are safe to eat is an important survival skill. Many animals are also edible, including domesticated livestock as well as wild insec ...
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Hematopoietic
Haematopoiesis (, from Greek , 'blood' and 'to make'; also hematopoiesis in American English; sometimes also h(a)emopoiesis) is the formation of blood cellular components. All cellular blood components are derived from haematopoietic stem cells. In a healthy adult person, approximately – new blood cells are produced daily in order to maintain steady state levels in the peripheral circulation.Semester 4 medical lectures at Uppsala University 2008 by Leif Jansson Process Haematopoietic stem cells (HSCs) Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types and tissues. HSCs are self-renewing cells: when they differentiate, at least some of their daughter cells remain as HSCs so the pool of stem cells is not depleted. This phenomenon is called asymmetric division. The other daughters of HSCs ( myeloid and lymphoid progenitor cells) can follow any of the other ...
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Bio-Rad
Bio-Rad Laboratories, Inc. is an American developer and manufacturer of specialized technological products for the life science research and clinical diagnostics markets. The company was founded in 1952 in Berkeley, California, by husband and wife team David and Alice Schwartz, both graduates of the University of California, Berkeley. Bio-Rad is based in Hercules, California, and has operations worldwide. Business segments Bio-Rad’s life science products primarily include instruments, software, consumables, reagents, and content for the areas of cell biology, gene expression, protein purification, protein quantitation, drug discovery and manufacture, food safety, and science education. These products are based on technologies to separate, purify, identify, analyze, and amplify biological materials such as antibodies, proteins, nucleic acids, cells, and bacteria.Bio-Rad Annual Report 2016 , http://www.bio-rad.com/webroot/web/pdf/corporate/annualreport/Annual_Report_2016.p ...
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ELISA
The enzyme-linked immunosorbent assay (ELISA) (, ) is a commonly used analytical biochemistry assay, first described by Eva Engvall and Peter Perlmann in 1971. The assay uses a solid-phase type of enzyme immunoassay (EIA) to detect the presence of a ligand (commonly a protein) in a liquid sample using antibodies directed against the protein to be measured. ELISA has been used as a diagnostic tool in medicine, plant pathology, and biotechnology, as well as a quality control check in various industries. In the most simple form of an ELISA, antigens from the sample to be tested are attached to a surface. Then, a matching antibody is applied over the surface so it can bind the antigen. This antibody is linked to an enzyme and then any unbound antibodies are removed. In the final step, a substance containing the enzyme's substrate is added. If there was binding, the subsequent reaction produces a detectable signal, most commonly a color change. Performing an ELISA involves at least ...
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Aspergillosis
Aspergillosis is a fungal infection of usually the lungs, caused by the genus ''Aspergillus'', a common mould that is breathed in frequently from the air around, but does not usually affect most people. It generally occurs in people with lung diseases such as asthma, cystic fibrosis or tuberculosis, or those who have had a stem cell or organ transplant, and those who cannot fight infection because of medications they take such as steroids and some cancer treatments. Rarely, it can affect skin. Aspergillosis occurs in humans, birds and other animals. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in people with severely compromised immune systems, e.g. those undergoing bone marrow transplantation. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses, such as asthma, cystic fibrosis, sarcoidosis, tuberculosis, or chronic obstructive pulmonary disease. Most ...
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Aspergillus
'''' () is a genus consisting of several hundred mold species found in various climates worldwide. ''Aspergillus'' was first catalogued in 1729 by the Italian priest and biologist Pier Antonio Micheli. Viewing the fungi under a microscope, Micheli was reminded of the shape of an ''aspergillum'' (holy water sprinkler), from Latin ''spargere'' (to sprinkle), and named the genus accordingly. Aspergillum is an asexual spore-forming structure common to all ''Aspergillus'' species; around one-third of species are also known to have a sexual stage. While some species of ''Aspergillus'' are known to cause fungal infections, others are of commercial importance. Taxonomy Species ''Aspergillus'' consists of 837 species of fungi. Growth and distribution ''Aspergillus'' is defined as a group of conidial fungi—that is, fungi in an asexual state. Some of them, however, are known to have a teleomorph (sexual state) in the Ascomycota. With DNA evidence, all members of the genus '' ...
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Investigative Ophthalmology & Visual Science
''Investigative Ophthalmology & Visual Science'' (''IOVS'') is an online journal published by the Association for Research in Vision and Ophthalmology (ARVO). History The journal was established as an official publication of the Association for Research in Ophthalmology (later renamed the Association for Research in Vision and Ophthalmology). The first issue of ''Investigative Ophthalmology'' was published in January 1962, with Bernard Becker, MD, as the Executive Editor. The title was changed to ''Investigative Ophthalmology & Visual Science'' in 1977.Colson, KS. Brief history of ''Investigative Ophthalmology & Visual Science''. In Chader GJ, Frank RN, Kaufman PL, Beebe DC, eds. ''The Best of'' Investigative Ophthalmology & Visual Science'': The First 50 Years 1962-2012''. Rockville, MD: ARVO; 2012:1-5. Abstracts from the ARVO Annual Meeting have been published as an issue of ''IOVS'' since 1977. Also in 1977, ''IOVS'' was accepted for inclusion in ''Index Medicus'' (and later ...
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