Bio-Rad Laboratories, Inc. is an American developer and manufacturer of specialized technological products for the

life science Life is a quality that distinguishes matter that has biological processes, such as signaling and self-sustaining processes, from that which does not, and is defined by the capacity for growth, reaction to stimuli, metabolism, energy t ...

research and clinical diagnostics markets. The company was founded in 1952 in

Berkeley, California Berkeley ( ) is a city on the eastern shore of San Francisco Bay in northern Alameda County, California, United States. It is named after the 18th-century Irish bishop and philosopher George Berkeley. It borders the cities of Oakland and Emer ...

, by husband and wife team David and

Alice Schwartz Alice Schwartz (born 1925/1926) is an American billionaire businesswoman. According to ''Forbes'', Schwartz has an estimated net worth of US$2.4 billion as of July 2022. Biography Schwartz graduated from the University of California, Berkeley ...

, both graduates of the University of California, Berkeley. Bio-Rad is based in Hercules, California, and has operations worldwide.

Business segments

Bio-Rad’s life science products primarily include instruments, software, consumables, reagents, and content for the areas of

cell biology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and ...

gene expression Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect. The ...

protein purification Protein purification is a series of processes intended to isolate one or a few proteins from a complex mixture, usually cells, tissues or whole organisms. Protein purification is vital for the specification of the function, structure and interact ...

, protein quantitation,

drug discovery In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by ...

and manufacture,

food safety Food safety (or food hygiene) is used as a scientific method/discipline describing handling, preparation, and storage of food in ways that prevent food-borne illness. The occurrence of two or more cases of a similar illness resulting from t ...

, and science education. These products are based on technologies to separate, purify, identify, analyze, and amplify biological materials such as

antibodies An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...

proteins Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

nucleic acids Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main clas ...

, cells, and

bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...

.Bio-Rad Annual Report 2016 , http://www.bio-rad.com/webroot/web/pdf/corporate/annualreport/Annual_Report_2016.pdf Bio-Rad’s diagnostic products and systems use a range of technologies and provide clinical information in the blood transfusion, diabetes monitoring, autoimmune, and infectious disease testing markets. These products are used to support the diagnosis, monitoring, and treatment of diseases and other medical conditions.

History

Bio-Rad Laboratories was founded in 1952 by David Schwartz and his wife Alice, both recent graduates of the

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...

. In 1976, Bio-Rad acquired Environmental Chemical Specialties (ECS), a producer of human control serum. In 2011, Bio-Rad acquired a new technology, droplet digital PCR. Droplet digital PCR allows scientists to distinguish rare sequences in tumors and precisely measure copy number variation. In January 2013, Bio-Rad purchased AbD Serotec, a division of MorphoSys AG. This added Serotec’s more than 15,000 antibodies, kits, and accessories to Bio-Rad’s portfolio of research and clinical diagnostic products. In 2016, the company had direct distribution channels in over 35 countries outside the United States through subsidiaries whose focus is sales, customer service and product distribution. In some locations outside and inside these 35 countries, sales efforts were supplemented by distributors and agents. In 2017, Bio-Rad acquired RainDance Technologies, a droplet-based PCR systems manufacturer. In March 2021, Bio-Rad announced a partnership with

Roche F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX ...

Vickers Instruments

In 1989, Bio-Rad purchased the British instrument-making firm,

Vickers Vickers was a British engineering company that existed from 1828 until 1999. It was formed in Sheffield as a steel foundry by Edward Vickers and his father-in-law, and soon became famous for casting church bells. The company went public in 18 ...

(1828 - 1999), apart from their defense products, which were sold to

British Aerospace British Aerospace plc (BAe) was a British aircraft, munitions and defence-systems manufacturer. Its head office was at Warwick House in the Farnborough Aerospace Centre in Farnborough, Hampshire. Formed in 1977, in 1999 it purchased Marconi ...

. This company had been known until 1963 as Cooke, Troughton & Simms. Cooke, Troughton & Simms was formed in 1922 by the merging of T. Cooke & Sons, a York-based instrument maker founded in 1837 by the self-taught schoolmaster Thomas Cooke, and the London instrument-maker,

Troughton & Simms Troughton & Simms was a British scientific instrument firm. It was formed when Edward Troughton in his old age took on William Simms as a partner in 1826. It became a limited company in 1915 and in 1922 it merged with T. Cooke & Sons to form ...

founded in 1828 by

Edward Troughton Edward Troughton FRS FRSE FAS (October 1753 – 12 June 1835) was a British instrument maker who was notable for making telescopes and other astronomical instruments. Life Troughton was born at Corney, Cumberland, the youngest of six child ...

who began his apprenticeship in 1773.

Bioradiations

''Bioradiations'' is an online

magazine A magazine is a periodical publication, generally published on a regular schedule (often weekly or monthly), containing a variety of content. They are generally financed by advertising, purchase price, prepaid subscriptions, or by a combinatio ...

created by Bio-Rad that offers researchers case studies, whitepapers, tips, techniques, and topics related to Bio-Rad products and services. ''Bioradiations'' began as a print magazine that was launched in 1965BioCompare
/ref> and was printed until 2011 and replaced with the online publication.

References

External links