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Formononetin
Formononetin is an O-methylated isoflavone. Natural occurrences Formononetin is found in a number of plants and herbs such as red clover. Along with other phytoestrogens, it predominantly occurs in leguminous plants and Fabaceae, particularly in beans, such as green beans, lima beans, soy and many others, as the free aglycone or in form of its glucoside ononin. It can also be found in ''Maackia amurensis'' cell cultures. Pharmacodynamics Formononetin promotes angiogenesis. It is also involved in expressing the gene and proteins that are needed to make IgE Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) " isotype") that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε c .... Derivatives Ononin is the 7-''O''-β-D-glucopyranoside of formononetin. References {{Isoflavone O-methylated isoflavones ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ononin
Ononin is an isoflavone glycoside, the 7-''O''-β-D-glucopyranoside of formononetin, which in turn is the 4'-''O''-methoxy derivative of the parent isoflavone daidzein. Natural sources Ononin is a major isoflavone found in a number of plants and herbs like soybean and Glycyrrhiza uralensis. Pharmacokinetics Intestinal bacterial metabolic pathways may include demethylation and deglycosylation. It follows that formation of formononetin and/or daidzein is possible. Pharmacodynamics An ''in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology ...'' anti-inflammatory effect on lipopolysaccharide (LPS)-induced inflammation has been demonstrated in one study. References {{Isoflavone O-methylated isoflavones Isoflavone glucosides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ononin
Ononin is an isoflavone glycoside, the 7-''O''-β-D-glucopyranoside of formononetin, which in turn is the 4'-''O''-methoxy derivative of the parent isoflavone daidzein. Natural sources Ononin is a major isoflavone found in a number of plants and herbs like soybean and Glycyrrhiza uralensis. Pharmacokinetics Intestinal bacterial metabolic pathways may include demethylation and deglycosylation. It follows that formation of formononetin and/or daidzein is possible. Pharmacodynamics An ''in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called " test-tube experiments", these studies in biology ...'' anti-inflammatory effect on lipopolysaccharide (LPS)-induced inflammation has been demonstrated in one study. References {{Isoflavone O-methylated isoflavones Isoflavone glucosides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Red Clover
''Trifolium pratense'', the red clover, is a herbaceous species of flowering plant in the bean family Fabaceae, native to Europe, Western Asia, and northwest Africa, but planted and naturalized in many other regions. Description Red clover is a herbaceous, short-lived perennial plant, variable in size, growing to tall. It has a deep taproot which makes it tolerant to drought and gives it a good soil structuring effect. The leaves are alternate, trifoliate (with three leaflets), each leaflet long and broad, green with a characteristic pale crescent in the outer half of the leaf; the petiole is long, with two basal stipules that are abruptly narrowed to a bristle-like point. The flowers are dark pink with a paler base, long, produced in a dense inflorescence, and are mostly visited by bumblebees. Distribution The red clover is native to Europe, Western Asia, and northwest Africa, but it has been naturalized in other continents, like North and South America. Specifical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytoestrogens
A phytoestrogen is a plant-derived xenoestrogen (see estrogen) not generated within the endocrine system, but consumed by eating plants or manufactured foods. Also called a "dietary estrogen", it is a diverse group of naturally occurring nonsteroidal plant compounds that, because of its structural similarity with estradiol (17-β-estradiol), have the ability to cause estrogenic or antiestrogenic effects. Phytoestrogens are not essential nutrients because their absence from the diet does not cause a disease, nor are they known to participate in any normal biological function. Common foods containing phytoestrogens are soy protein, beans, oats, barley, rice, coffee, apples, carrots (see Food Sources section below for bigger list). Its name comes from the Greek ''phyto'' ("plant") and ''estrogen'', the hormone which gives fertility to female mammals. The word "estrus" - Greek οίστρος - means "sexual desire", and "gene" - Greek γόνο - is "to generate". It has been hypoth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leguminous
A legume () is a plant in the family Fabaceae (or Leguminosae), or the fruit or seed of such a plant. When used as a dry grain, the seed is also called a pulse. Legumes are grown agriculturally, primarily for human consumption, for livestock forage and silage, and as soil-enhancing green manure. Well-known legumes include beans, soybeans, chickpeas, peanuts, lentils, lupins, mesquite, carob, tamarind, alfalfa, and clover. Legumes produce a botanically unique type of fruit – a simple dry fruit that develops from a simple carpel and usually dehisces (opens along a seam) on two sides. Legumes are notable in that most of them have symbiotic nitrogen-fixing bacteria in structures called root nodules. For that reason, they play a key role in crop rotation. Terminology The term ''pulse'', as used by the United Nations' Food and Agriculture Organization (FAO), is reserved for legume crops harvested solely for the dry seed. This excludes green beans and green peas, which are consid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fabaceae
The Fabaceae or Leguminosae,International Code of Nomenclature for algae, fungi, and plants. Article 18.5 states: "The following names, of long usage, are treated as validly published: ....Leguminosae (nom. alt.: Fabaceae; type: Faba Mill. Vicia L.; ... When the Papilionaceae are regarded as a family distinct from the remainder of the Leguminosae, the name Papilionaceae is conserved against Leguminosae." English pronunciations are as follows: , and . commonly known as the legume, pea, or bean family, are a large and agriculturally important of |
Beans
A bean is the seed of several plants in the family Fabaceae, which are used as vegetables for human or animal food. They can be cooked in many different ways, including boiling, frying, and baking, and are used in many traditional dishes throughout the world. Terminology The word "bean" and its Germanic cognates (e.g. German '' Bohne'') have existed in common use in West Germanic languages since before the 12th century, referring to broad beans, chickpeas, and other pod-borne seeds. This was long before the New World genus '' Phaseolus'' was known in Europe. After Columbian-era contact between Europe and the Americas, use of the word was extended to pod-borne seeds of ''Phaseolus'', such as the common bean and the runner bean, and the related genus ''Vigna''. The term has long been applied generally to many other seeds of similar form, such as Old World soybeans, peas, other vetches, and lupins, and even to those with slighter resemblances, such as coffee beans, vanilla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Green Beans
Green beans are young, unripe fruits of various cultivars of the common bean (''Phaseolus vulgaris''), although immature or young pods of the runner bean (''Phaseolus coccineus''), yardlong bean ( ''Vigna unguiculata'' subsp. ''sesquipedalis''), and hyacinth bean (''Lablab purpureus'') are used in a similar way. Green beans are known by many common names, including French beans (), string beans (although most modern varieties are "stringless"), and snap beans or simply "snaps". In the Philippines, they are also known as "Baguio beans" or "" to distinguish them from yardlong beans. They are distinguished from the many other varieties of beans in that green beans are harvested and consumed with their enclosing pods, before the bean seeds inside have fully matured. An analogous practice is the harvest and consumption of unripened pea pods, as is done with snow peas or sugar snap peas. Culinary use As common food in many countries, green beans are sold fresh, canned, and fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lima Beans
A lima bean (''Phaseolus lunatus''), also commonly known as the butter bean, sieva bean, double bean, Madagascar bean, or wax bean is a legume grown for its edible seeds or beans. Origin and uses ''Phaseolus lunatus'' is found in Meso- and South America. Two gene pools of cultivated lima beans point to independent domestication events. The Mesoamerican lima bean is distributed in neotropical lowlands, while the other is found in the western Andes. They were discovered in Peru and may have been the first plant that was brought up under civilization by the native farmers. The Andes domestication took place around 2000 BC and produced a large-seeded variety (lima type), while the second, taking place in Mesoamerica around 800 AD, produced a small-seeded variety (Sieva type). By around 1300, cultivation had spread north of the Rio Grande, and, in the 1500s, the plant began to be cultivated in the Old World. The small-seeded (Sieva) type is found distributed from Mexico to Argent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aglycone
An aglycone (aglycon or genin) is the compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. For example, the aglycone of a cardiac glycoside would be a steroid molecule. Detection A way to identify aglycone is proposed to extract it from Agave spp. by using H-NMR and Heteronuclear multiple bond correlation (HMBC) experiments. The HMBC experiment can be combined with other techniques such as mass spectrometry to further examine the structure and the function of aglycone. Samples of glycones and glycosides from limonoids can be simultaneously quantified through a high performance liquid chromatography (HPLC) method, where a binary solvent system and a diode array detector separate and detect them at a sensitivity of 0.25-0.50 µg. Clinical significance A study on molecular markers in human aortic endothelial cells published that aglycone stopped cell migration but not monocyte adhesion, which is the initial step of atherosclerotic plaq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucoside
A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes. The name was originally given to plant products of this nature, in which the other part of the molecule was, in the greater number of cases, an aromatic aldehydic or phenolic compound (exceptions are Jinigrin and Jalapin or Scammonin). It has now been extended to include synthetic ethers, such as those obtained by acting on alcoholic glucose solutions with hydrochloric acid, and also the polysaccharoses, e.g. cane sugar, which appear to be ethers also. Although glucose is the most common sugar present in glucosides, many are known which yield rhamnose or iso-dulcite; these may be termed pentosides. Much attention has been given to the non-sugar parts (aglyca) of the molecules; the constitutions of many have been determined, and the compounds synthesi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
