Farmyard Pox
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Farmyard Pox
Farmyard pox is a group of closely related ''Parapoxviruses'' of sheep and cattle that can cause bovine papular stomatitis, orf and milker's nodule in humans. See also * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ... References Virus-related cutaneous conditions {{Cutaneous-infection-stub ...
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Orf (disease)
Orf is a farmyard pox, a type of zoonosis. It causes small pustules in the skin of primarily sheep and goats, but can also occur on the hands of humans. A pale halo forms around a red centre. It may persist for several weeks before crusting and then either resolves or leaves a hard lump. There is usually only one lesion, but there may be many, and they are not painful. Sometimes there are swollen lymph glands. It is caused by a ''Parapoxvirus''. It can occur in humans who handle infected animals or contaminated objects. One third of cases may develop erythema multiforme. Once resolved, a person can still be infected again. Generally, treatment options are limited. Injecting the lesion with cidofovir or applying imiquimod has been tried. It is sometimes necessary to cut them out. The vaccine used in sheep to prevent orf is live and has been known to cause disease in humans. The disease is endemic in livestock herds worldwide. A recent outbreak emerged in southwest Ethiopia betw ...
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Infectious Diseases
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis'' ...
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Bovine Papular Stomatitis
Bovine papular stomatitis is a farmyard pox caused by ''Bovine papular stomatitis virus'' (BPSV), which can spread from infected cattle to cause disease in milkers, farmers and veterinarians. Generally there is usually one or a few skin lesions typically on the hands or forearm. The disease is generally mild. BPSV is a member of the family ''Poxviridae'' and the genus ''Parapoxvirus''. Spread typically occurs by direct contact with the infected animal, but has been reported in people without direct contact. It may appear similar to foot-and-mouth disease. It occurs worldwide in cattle Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult mal .... In other animals the lesions are reddish, raised, sometimes ulcerative lesions on the lips, muzzle, and in the mouth. It usually occurs before the ...
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Milker's Nodule
Milker's nodules are a cutaneous condition that is most commonly transmitted from the udders of infected cows. Milker's nodule is caused by Paravaccinia virus. The disease in humans is nearly identical to Orf. __TOC__ Pathogen Milker's nodules is a zoonotic dermatosis. It was caused by double-stranded DNA virus of the ''Parapoxvirus'' genus. ''Parapoxvirus'' usually presents in the saliva, nasal secretions, and in lesions over the udder, trunk, and limbs of affected bovine cattle. It may transmitted by direct or indirect contact of lesion. See also * Farmyard pox * List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ... References Virus-related cutaneous conditions {{Cutaneous-infection-stub ...
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Parapoxvirus
''Parapoxvirus'' is a genus of viruses, in the family ''Poxviridae'', in the subfamily ''Chordopoxvirinae''. Like all members of the family Poxviridae, they are oval, relatively large, double-stranded DNA viruses. Parapoxviruses have a unique spiral coat that distinguishes them from other poxviruses. Parapoxviruses infect vertebrates, including a wide selection of mammals, and humans. Not all parapoxviruses are zoonotic. Notable zoonotic hosts of parapoxviruses include sheep, goats, and cattle. The most recent species of parapoxviruses has been found in New Zealand red deer. There are also some tentative species in the genus, including Auzduk disease virus, Chamois contagious ecthyma virus, and sealpox virus. Structure Viruses in ''Parapoxvirus'' are enveloped, with ovoid geometries. These viruses are about 140–170 nm wide and 220–300 nm long, and have a regular surface structure; tubules with a diameter of 10–20 nm form a criss-cross pattern. Genomes ar ...
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Bovine Papular Stomatitis
Bovine papular stomatitis is a farmyard pox caused by ''Bovine papular stomatitis virus'' (BPSV), which can spread from infected cattle to cause disease in milkers, farmers and veterinarians. Generally there is usually one or a few skin lesions typically on the hands or forearm. The disease is generally mild. BPSV is a member of the family ''Poxviridae'' and the genus ''Parapoxvirus''. Spread typically occurs by direct contact with the infected animal, but has been reported in people without direct contact. It may appear similar to foot-and-mouth disease. It occurs worldwide in cattle Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult mal .... In other animals the lesions are reddish, raised, sometimes ulcerative lesions on the lips, muzzle, and in the mouth. It usually occurs before the ...
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Skin Lesion
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails). While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described. Classification of these conditions often presents many nosological challenges, since underlying causes and pathogenetics are often not known. Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology ( chronic blistering conditions), cause (skin conditions resul ...
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