Fusobacterium Infections
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Fusobacterium Infections
''Fusobacterium'' is a genus of anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends. Strains of ''Fusobacterium'' cause several human diseases, including periodontal diseases, Lemierre's syndrome, and topical skin ulcers. Although older sources state that ''Fusobacterium'' is part of the normal flora of the human oropharynx, the current consensus is that ''Fusobacterium'' should always be treated as a pathogen. ''F. prausnitzii'', a gut commensal associated with healthy patients, was completely reclassified as '' Faecalibacterium'' (''Clostridiales'':''Ruminococcaceae'') in 2002. Clinical relevance ''Fusobacterium'' is often associated with ulcerative colitis. Research of colon cancer has also shown an overrepresentation of ''Fusobacterium'', both in feces of patients and tumor issue itself. Whether ''Fusobacterium'' causes these diseases or only colonizes existing tumours, rema ...
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LPSN
List of Prokaryotic names with Standing in Nomenclature (LPSN) is an online database that maintains information on the naming and taxonomy of prokaryotes, following the taxonomy requirements and rulings of the International Code of Nomenclature of Prokaryotes The International Code of Nomenclature of Prokaryotes (ICNP) formerly the International Code of Nomenclature of Bacteria (ICNB) or Bacteriological Code (BC) governs the scientific names for Bacteria and Archaea.P. H. A. Sneath, 2003. A short hist .... The database was curated from 1997 to June 2013 by Jean P. Euzéby. From July 2013 to January 2020, LPSN was curated by Aidan C. Parte. In February 2020, a new version of LPSN was published as a service of the Leibniz Institute DSMZ, thereby also integrating the Prokaryotic Nomenclature Up-to-date service. References External links List of Prokaryotic names with Standing in Nomenclature
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Fusobacterium Pullicola
''Fusobacterium'' is a genus of anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends. Strains of ''Fusobacterium'' cause several human diseases, including periodontal diseases, Lemierre's syndrome, and topical skin ulcers. Although older sources state that ''Fusobacterium'' is part of the normal flora of the human oropharynx, the current consensus is that ''Fusobacterium'' should always be treated as a pathogen. ''F. prausnitzii'', a gut commensal associated with healthy patients, was completely reclassified as ''Faecalibacterium'' (''Clostridiales'':''Ruminococcaceae'') in 2002. Clinical relevance ''Fusobacterium'' is often associated with ulcerative colitis. Research of colon cancer has also shown an overrepresentation of ''Fusobacterium'', both in feces of patients and tumor issue itself. Whether ''Fusobacterium'' causes these diseases or only colonizes existing tumours, remains undete ...
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Skin Ulcers
An ulcer is a sore on the skin or a mucous membrane, accompanied by the disintegration of tissue. Ulcers can result in complete loss of the epidermis and often portions of the dermis and even subcutaneous fat. Ulcers are most common on the skin of the lower extremities and in the gastrointestinal tract. An ulcer that appears on the skin is often visible as an inflamed tissue with an area of reddened skin. A skin ulcer is often visible in the event of exposure to heat or cold, irritation, or a problem with blood circulation. They can also be caused due to a lack of mobility, which causes prolonged pressure on the tissues. This stress in the blood circulation is transformed to a skin ulcer, commonly known as bedsores or decubitus ulcers. Ulcers often become infected, and pus forms. Signs and symptoms Skin ulcers appear as open craters, often round, with layers of skin that have eroded. The skin around the ulcer may be red, swollen, and tender. Patients may feel pain on the skin ar ...
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Lemierre's Syndrome
Lemierre's syndrome is infectious thrombophlebitis of the internal jugular vein. It most often develops as a complication of a bacterial pharyngitis, sore throat infection in young, otherwise healthy adults. The thrombophlebitis is a serious condition and may lead to further systemic complications such as bacteremia, bacteria in the blood or Septic embolism, septic emboli. Lemierre's syndrome occurs most often when a bacterial (e.g., ''Fusobacterium necrophorum'') throat infection progresses to the formation of a peritonsillar abscess. Deep in the abscess, anaerobic bacteria can flourish. When the abscess wall ruptures internally, the drainage carrying bacteria seeps through the soft tissue and infects the nearby structures. Spread of infection to the nearby internal jugular vein provides a gateway for the spread of bacteria through the bloodstream. The inflammation surrounding the vein and compression of the vein may lead to thrombosis, blood clot formation. Pieces of the potentia ...
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Periodontal Disease
Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the tissues surrounding the teeth. In its early stage, called gingivitis, the gums become swollen and red and may bleed. It is considered the main cause of tooth loss for adults worldwide.V. Baelum and R. Lopez, “Periodontal epidemiology: towards social science or molecular biology?,”Community Dentistry and Oral Epidemiology, vol. 32, no. 4, pp. 239–249, 2004.Nicchio I, Cirelli T, Nepomuceno R, et al. Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects' Periodontal, Glycemic, and Lipid Profiles Journal of Diabetes Research. 2021 Jan;2021. PMCID: PMC8601849. In its more serious form, called periodontitis, the gums can pull away from the tooth, bone can be lost, and the teeth may loosen or fall out. Bad breath may also occur. Periodontal disease is generally due to bacteria in the mouth ...
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Bacillus (shape)
A bacillus (), also called a bacilliform bacterium or often just a rod (when the context makes the sense clear), is a rod-shaped bacterium or archaeon. Bacilli are found in many different taxonomic groups of bacteria. However, the name ''Bacillus'', capitalized and italicized, refers to a specific genus of bacteria. The name Bacilli, capitalized but not italicized, can also refer to a less specific taxonomic group of bacteria that includes two orders, one of which contains the genus ''Bacillus''. When the word is formatted with lowercase and not italicized, 'bacillus', it will most likely be referring to shape and not to the genus at all. Bacilliform bacteria are also often simply called rods when the bacteriologic context is clear. Bacilli usually divide in the same plane and are solitary, but can combine to form diplobacilli, streptobacilli, and palisades. * Diplobacilli: Two bacilli arranged side by side with each other. * Streptobacilli: Bacilli arranged in chains. * Coccobac ...
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Cell (biology)
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body
in Chapter 21 of
Molecular Biology of the Cell
'' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos. It is also common to describe small molecules such as ...
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Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', ''Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipo ...
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Anaerobic Organism
An anaerobic organism or anaerobe is any organism that does not require molecular oxygen for growth. It may react negatively or even die if free oxygen is present. In contrast, an aerobic organism (aerobe) is an organism that requires an oxygenated environment. Anaerobes may be unicellular (e.g. protozoans, bacteria) or multicellular. Most fungi are obligate aerobes, requiring oxygen to survive. However, some species, such as the Chytridiomycota that reside in the rumen of cattle, are obligate anaerobes; for these species, anaerobic respiration is used because oxygen will disrupt their metabolism or kill them. Deep waters of the ocean are a common anoxic environment. First observation In his letter of 14 June 1680 to The Royal Society, Antonie van Leeuwenhoek described an experiment he carried out by filling two identical glass tubes about halfway with crushed pepper powder, to which some clean rain water was added. Van Leeuwenhoek sealed one of the glass tubes using a flame an ...
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Fusobacterium Watanabei
''Fusobacterium'' is a genus of anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends. Strains of ''Fusobacterium'' cause several human diseases, including periodontal diseases, Lemierre's syndrome, and topical skin ulcers. Although older sources state that ''Fusobacterium'' is part of the normal flora of the human oropharynx, the current consensus is that ''Fusobacterium'' should always be treated as a pathogen. ''F. prausnitzii'', a gut commensal associated with healthy patients, was completely reclassified as ''Faecalibacterium'' (''Clostridiales'':''Ruminococcaceae'') in 2002. Clinical relevance ''Fusobacterium'' is often associated with ulcerative colitis. Research of colon cancer has also shown an overrepresentation of ''Fusobacterium'', both in feces of patients and tumor issue itself. Whether ''Fusobacterium'' causes these diseases or only colonizes existing tumours, remains undete ...
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Fusobacterium Vincentii
''Fusobacterium'' is a genus of anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends. Strains of ''Fusobacterium'' cause several human diseases, including periodontal diseases, Lemierre's syndrome, and topical skin ulcers. Although older sources state that ''Fusobacterium'' is part of the normal flora of the human oropharynx, the current consensus is that ''Fusobacterium'' should always be treated as a pathogen. ''F. prausnitzii'', a gut commensal associated with healthy patients, was completely reclassified as ''Faecalibacterium'' (''Clostridiales'':''Ruminococcaceae'') in 2002. Clinical relevance ''Fusobacterium'' is often associated with ulcerative colitis. Research of colon cancer has also shown an overrepresentation of ''Fusobacterium'', both in feces of patients and tumor issue itself. Whether ''Fusobacterium'' causes these diseases or only colonizes existing tumours, remains undete ...
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Fusobacterium Varium
''Fusobacterium'' is a genus of anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. Individual cells are slender, rod-shaped bacilli with pointed ends. Strains of ''Fusobacterium'' cause several human diseases, including periodontal diseases, Lemierre's syndrome, and topical skin ulcers. Although older sources state that ''Fusobacterium'' is part of the normal flora of the human oropharynx, the current consensus is that ''Fusobacterium'' should always be treated as a pathogen. ''F. prausnitzii'', a gut commensal associated with healthy patients, was completely reclassified as ''Faecalibacterium'' (''Clostridiales'':''Ruminococcaceae'') in 2002. Clinical relevance ''Fusobacterium'' is often associated with ulcerative colitis. Research of colon cancer has also shown an overrepresentation of ''Fusobacterium'', both in feces of patients and tumor issue itself. Whether ''Fusobacterium'' causes these diseases or only colonizes existing tumours, remains undete ...
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