Frog Test
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Frog Test
The frog test is a pregnancy testing method relying on frogs to show the pregnancy status of women. Provided that immunological pregnancy tests were not yet developed before 1960s, women living a century ago relied on urine-based pregnancy tests using different animals, ranging from mice to frogs. Nowadays, the advancement in Medical Technology, medical technology has enabled women to accurately check their pregnancy status by using 'pee-on-a-stick' pregnancy test kits at home. Before these accessible and convenient test kits were invented, scientists strived to discover a way in spotting pregnancy-related hormones by a natural, simple test, where animals were often included as clinical tools to facilitate the process. The frog test or frog pregnancy test is one of the past prevalent pregnancy scanning methods. Throughout history, there have been different frog tests with the aim of indicating the pregnancy status of women. The most well known frog test, is the Hogben test, which ...
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Pregnancy
Pregnancy is the time during which one or more offspring develops ( gestates) inside a woman's uterus (womb). A multiple pregnancy involves more than one offspring, such as with twins. Pregnancy usually occurs by sexual intercourse, but can also occur through assisted reproductive technology procedures. A pregnancy may end in a live birth, a miscarriage, an induced abortion, or a stillbirth. Childbirth typically occurs around 40 weeks from the start of the last menstrual period (LMP), a span known as the gestational age. This is just over nine months. Counting by fertilization age, the length is about 38 weeks. Pregnancy is "the presence of an implanted human embryo or fetus in the uterus"; implantation occurs on average 8–9 days after fertilization. An '' embryo'' is the term for the developing offspring during the first seven weeks following implantation (i.e. ten weeks' gestational age), after which the term ''fetus'' is used until birth. Signs an ...
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Human Chorionic Gonadotropin
Human chorionic gonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells that are surrounding a growing embryo (syncytiotrophoblast initially), which eventually forms the placenta after implantation. The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant may lead to a cancer diagnosis and, if high enough, paraneoplastic syndromes, however, it is not known whether this production is a contributing cause, or an effect of carcinogenesis. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages. Various endogenous forms of hCG exist. The measurement of these diverse forms is used in the diagnosis of pregnancy and a variety of disease states. Preparations of hCG from various sources have also been used therapeutically, by ...
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Selmar Aschheim
Selmar Aschheim (4 October 1878 – 15 February 1965) was a German gynecologist who was a native resident of Berlin. Born into a Jewish family, in 1902 he received a doctorate of medicine in Freiburg, and later became director of the laboratory of the ''Universitäts-Frauenklinik'' at the Berlin Charité. In 1930 Aschheim attained the chair of biological research in gynecology at the University of Berlin. In 1933 he fled Nazi Germany and moved to Paris, where he worked in medical research at the Hôpital Beaujon. Aschheim was a specialist concerning gynecological histology and hormone research. In 1928 with endocrinologist Bernhard Zondek (1891–1966), he isolated the gonadotropic hormone known as human chorionic gonadotropin (hCG), which was discovered in the urine of pregnant women. From their research the "Aschheim-Zondek test" for pregnancy was created, which involved injection of a patient's urine into an immature laboratory mouse. If the rodent displayed an estrous rea ...
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European Tree Frog
The European tree frog (''Hyla arborea'') is a small tree frog. As traditionally defined, it was found throughout much of Europe, Asia and northern Africa,Frost, Darrel R. ''Amphibian Species of the World''. Allen Press, Inc., 1985, p. 126. but based on molecular genetic and other data several populations formerly included in it are now recognized as separate species (for example, '' H. intermedia'' of Italy and nearby, '' H. molleri'' of the Iberian Peninsula, '' H. meridionalis'' of parts of southwestern Europe and northern Africa, and '' H. orientalis'' of parts of Eastern Europe, Turkey and the Black Sea and Caspian Sea regions), limiting the true European tree frog to Europe from France to Poland and Greece.Duellman, William E. (2003). ''Grzimek's Animal Encyclopedia''. 2nd Ed., Vol. 2. Gale, p. 235.Stöck M., Dufresnes C., Litvinchuk S.N., Lymberakis P., Biollay S., Berroneau M., Borzée A., Ghali K., Ogielska M., and Perrin N. (2012). Cryptic diversity among Western Palearct ...
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Marsh Frog
The marsh frog (''Pelophylax ridibundus'') is a species of water frog native to Europe and parts of western Asia. Description The marsh frog is the largest type of frog in most of its range, with males growing to a size around 100 mm (3.9 in) SVL and females slightly larger (4 in) SVL. There is a large variation in colour and pattern, ranging from dark green to brown or grey, sometimes with some lighter green lines; a lighter line on the back is generally present. The frog will usually be darker coloured in early spring to absorb heat more efficiently. Tadpoles can reach up to 190 mm (7.3 in) in length, but this usually occurs in places with long winters where the tadpole has time to grow. Distribution and habitat They occur in a large part of Europe starting from western France and spreading out into the Middle East and about a quarter into Russia. There are also isolated populations in Saudi Arabia and the Russian Far East, along with some introduced populations in ...
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European Green Toad
The European green toad (''Bufotes viridis'') is a species of toad found in steppes, mountainous areas, semi-deserts, urban areas and other habitats in mainland Europe, ranging from far eastern France and Denmark to the Balkans and Western Russia. As historically defined, the species ranged east through the Middle East and Central Asia to western China, Mongolia and northwestern India, and south through Italy and the Mediterranean islands to North Africa. Following genetic and morphological reviews, 14 population (all largely or entirely Asian, except for the African and Balearic green toads) are now regarded as separate species. These species and the European green toad are placed in their own genus ''Bufotes'', but they were included in ''Bufo''. Description The spots on the back vary from green to dark brown and sometimes red spots appear, too. The underside is white or very lightly coloured. The European green toad will change colour in response to heat and light changes. ...
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Israel
Israel (; he, יִשְׂרָאֵל, ; ar, إِسْرَائِيل, ), officially the State of Israel ( he, מְדִינַת יִשְׂרָאֵל, label=none, translit=Medīnat Yīsrāʾēl; ), is a country in Western Asia. It is situated on the southeastern shore of the Mediterranean Sea and the northern shore of the Red Sea, and shares borders with Lebanon to the north, Syria to the northeast, Jordan to the east, and Egypt to the southwest. Israel also is bordered by the Palestinian territories of the West Bank and the Gaza Strip to the east and west, respectively. Tel Aviv is the economic and technological center of the country, while its seat of government is in its proclaimed capital of Jerusalem, although Israeli sovereignty over East Jerusalem is unrecognized internationally. The land held by present-day Israel witnessed some of the earliest human occupations outside Africa and was among the earliest known sites of agriculture. It was inhabited by the Canaanites ...
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Gonadotropic Hormone
Gonadotropins are glycoprotein hormones secreted by gonadotropic cells of the anterior pituitary of vertebrates. This family includes the mammalian hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH), the placental/ chorionic gonadotropins, human chorionic gonadotropin (hCG) and equine chorionic gonadotropin (eCG), as well as at least two forms of fish gonadotropins. These hormones are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function. LH and FSH are secreted by the anterior pituitary gland, while hCG and eCG are secreted by the placenta in pregnant humans and mares, respectively. The gonadotropins act on the gonads, controlling gamete and sex hormone production. Gonadotropin is sometimes abbreviated ''Gn''. The alternative spelling ''gonadotrophin'' which inaccurately implies a nourishing mechanism is also used. There are various preparations of gonadotropins for therapeutic use, mainly a ...
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Carlos Galli Mainini
Carlos may refer to: Places ;Canada * Carlos, Alberta, a locality ;United States * Carlos, Indiana, an unincorporated community * Carlos, Maryland, a place in Allegany County * Carlos, Minnesota, a small city * Carlos, West Virginia ;Elsewhere * Carlos (crater), Montes Apenninus, LQ12, Moon; a lunar crater near Mons Hadley People * Carlos (given name), including a list of name holders * Carlos (surname), including a list of name holders Sportspeople * Carlos (Timorese footballer) (born 1986) * Carlos (footballer, born 1995), Brazilian footballer * Carlos (footballer, born 1985), Brazilian footballer Others * Carlos (Calusa) (died 1567), king or paramount chief of the Calusa people of Southwest Florida * Carlos (DJ) (born 1966), British DJ * Carlos (singer) (1943—2008), French entertainer * Carlos the Jackal, a Venezuelan terrorist *Carlos (DJ) (born 2010) Guyanese DJ Arts and entertainment * ''Carlos'' (miniseries), 2010 biopic about the terrorist Carlos the Jackal ...
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Menstrual Cycle
The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that make pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the uterus (womb) to receive an embryo. These cycles are concurrent and coordinated, normally last between 21 and 35 days, with a median length of 28 days, and continue for about 30–45 years. Naturally occurring hormones drive the cycles; the cyclical rise and fall of the follicle stimulating hormone prompts the production and growth of oocytes (immature egg cells). The hormone estrogen stimulates the uterus lining ( endometrium) to thicken to accommodate an embryo should fertilization occur. The blood supply of the thickened lining provides nutrients to a successfully implanted embryo. If implantation does n ...
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Pharmacist
A pharmacist, also known as a chemist (Commonwealth English) or a druggist (North American and, archaically, Commonwealth English), is a healthcare professional who prepares, controls and distributes medicines and provides advice and instructions on the correct and safe use of medicines to achieve maximum benefit, minimal side effects and to avoid drug interactions. They also serve as primary care providers in the community. Pharmacists undergo university or graduate-level education to understand the biochemical mechanisms and actions of drugs, drug uses, therapeutic roles, side effects, potential drug interactions, and monitoring parameters. This is mated to anatomy, physiology, and pathophysiology. Pharmacists interpret and communicate this specialized knowledge to patients, physicians, and other health care providers. Among other licensing requirements, different countries require pharmacists to hold either a Bachelor of Pharmacy, Master of Pharmacy, or Doctor of Pharmacy d ...
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Rabbit Test
The rabbit test, or Friedman test, was an early pregnancy test developed in 1931 by Maurice Friedman and Maxwell Edward Lapham at the University of Pennsylvania. Test The hormone human chorionic gonadotropin (hCG) is produced during pregnancy and can be found in a pregnant woman's urine and blood; it indicates the presence of an implanted fertilized egg. An earlier test, known as the AZ test, was developed by Selmar Aschheim and Bernhard Zondek. When urine from a woman in the early months of pregnancy was injected into immature female mice, their ovaries would enlarge and show follicular maturation. The test was considered reliable, with an error rate of less than 2%. Friedman and Lapham's test was essentially identical, but replaced the mouse with a rabbit. A few days after the injection, the animal would be dissected and the size of her ovaries examined. The rabbit test became a widely used bioassay (animal-based test) to test for pregnancy. The term "rabbit test" wa ...
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