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Fingernail
A nail is a claw-like plate found at the tip of the fingers and toes on most primates. Nails correspond to the claws found in other animals. Fingernails and toenails are made of a tough protective protein called alpha-keratin, which is a polymer. Alpha-keratin is found in the hooves, claws, and horns of vertebrates. Structure The nail consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. Parts of the nail The matrix, sometimes called the ''matrix unguis'', keratogenous membrane, nail matrix, or onychostroma, is the active tissue (or germinal matrix) that generates cells, which harden as they move outward from the nail root to the nail plate. It is the part of the nail bed that is beneath the nail and contains nerves, lymph and blood vessels. The matrix produces cells that become the nail plate. The width and thickness of the nail plate is determined by the size, length, and thickness of the matrix, while the shape of the finger ...
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Lunula (anatomy)
The lunula, or lunulae (pl.) (), is the crescent-shaped whitish area of the bed of a fingernail or toenail. In humans, it appears by week 14 of gestation, and has a primary structural role in defining the free edge of the distal nail plate (the part of the nail that grows outward). Appearance It is located at the end of the nail (that is closest to the skin of the finger), but it still lies under the nail. It is not actually white but only appears so when it is seen through the nail. Outlining the nail matrix, the lunula is a very delicate part of the nail structure. If one damages the lunula, the nail will be permanently deformed. Even when the totality of the nail is removed, the lunula remains in place and is similar in appearance to another smaller fingernail embedded in the nail bed. In most cases, it is half-moon-shaped and has unique histologic features. Examinations concluded that the lunula is an area of loose dermis with lesser developed collagen bundles. It appears ...
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Primate
Primates are a diverse order of mammals. They are divided into the strepsirrhines, which include the lemurs, galagos, and lorisids, and the haplorhines, which include the tarsiers and the simians (monkeys and apes, the latter including humans). Primates arose 85–55 million years ago first from small terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment, including large brains, visual acuity, color vision, a shoulder girdle allowing a large degree of movement in the shoulder joint, and dextrous hands. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the 2010s, and three in the 2020s. Primates have large bra ...
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Eponychium
In human anatomy, the eponychium is the thickened layer of skin at the base of the fingernails and toenails. It can also be called the medial or proximal nail fold. The eponychium differs from the cuticle; the eponychium comprises live skin cells whilst the cuticle is dead skin cells. Its function is to protect the area between the nail and epidermis from exposure to bacteria. The vascularization pattern is similar to that of perionychium. In hoofed animals, the eponychium is the deciduous hoof capsule in fetuses and newborn foals, and is a part of the permanent hoof in older animals. The word ''eponychium'' comes . See also * Hyponychium The hyponychium is the area of epithelium, particularly the thickened portion, underlying the free edge of the nail plate on the nail. Its proximal border is immediately distal to distal limit of nail bed—a.k.a. the onychodermal band (the line ... * Lunula References Nail anatomy {{anatomy-stub ...
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Integumentary System
The integumentary system is the set of organs forming the outermost layer of an animal's body. It comprises the skin and its appendages, which act as a physical barrier between the external environment and the internal environment that it serves to protect and maintain the body of the animal. Mainly it is the body's outer skin. The integumentary system includes hair, scales, feathers, hooves, and nails. It has a variety of additional functions: it may serve to maintain water balance, protect the deeper tissues, excrete wastes, and regulate body temperature, and is the attachment site for sensory receptors which detect pain, sensation, pressure, and temperature. Structure Skin The skin is one of the largest organs of the body. In humans, it accounts for about 12 to 15 percent of total body weight and covers 1.5 to 2 m2 of surface area. The skin (integument) is a composite organ, made up of at least two major layers of tissue: the epidermis and the dermis. The epidermis is ...
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Paronychia
Paronychia is an inflammation of the skin around the nail, which can occur suddenly, when it is usually due to the bacterium '' Staphylococcus aureus'', or gradually when it is commonly caused by the fungus ''Candida albicans''. The term is from el, παρωνυχία from ''para'' 'around', ''onyx'' 'nail', and the abstract noun suffix '' -ia''. Risk factors include repeatedly washing hands and trauma to the cuticle such as may occur from repeated nail biting or hangnails. Treatment includes antibiotics and antifungals, and if pus is present, the consideration of incision and drainage. Paronychia is commonly misapplied as a synonym for herpetic whitlow or felon. Definition and etymology Paronychia is an inflammation of the skin around the nail, which can occur suddenly (acute), when it is usually due to the bacterium ''Staphylococcus aureus'', or gradually (chronic) when it is commonly caused by ''Candida albicans''. The term is from el, παρωνυχία from ''par ...
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Cuticle
A cuticle (), or cuticula, is any of a variety of tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Various types of "cuticle" are non- homologous, differing in their origin, structure, function, and chemical composition. Human anatomy In human anatomy, "cuticle" can refer to several structures, but it is used in general parlance, and even by medical professionals, to refer to the thickened layer of skin surrounding fingernails and toenails (the eponychium), and to refer to the superficial layer of overlapping cells covering the hair shaft ( cuticula pili), consisting of dead cells, that locks the hair into its follicle. It can also be used as a synonym for the epidermis, the outer layer of skin. Cuticle of invertebrates In zoology, the invertebrate cuticle or cuticula is a multi-layered structure outside the epidermis of many invertebrates, notably roundworms and arthropods, in which it forms an exoskeleton ...
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Keratin
Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. Alpha-keratin (α-keratin) is a type of keratin found in vertebrates. It is the key structural material making up scales, hair, nails, feathers, horns, claws, hooves, and the outer layer of skin among vertebrates. Keratin also protects epithelial cells from damage or stress. Keratin is extremely insoluble in water and organic solvents. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong unmineralized epidermal appendages found in reptiles, birds, amphibians, and mammals. Excessive keratinization participate in fortification of certain tissues such as in horns of cattle and rhinos, and armadillos' osteoderm. The only other biological matter known to approximate the toughness of keratinized tissue is chitin. Keratin comes in two types, the primitive, softer forms found in all vertebrates and harder, derived forms found only amon ...
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Dehydration
In physiology, dehydration is a lack of total body water, with an accompanying disruption of metabolic processes. It occurs when free water loss exceeds free water intake, usually due to exercise, disease, or high environmental temperature. Mild dehydration can also be caused by immersion diuresis, which may increase risk of decompression sickness in divers. Most people can tolerate a 3-4% decrease in total body water without difficulty or adverse health effects. A 5-8% decrease can cause fatigue and dizziness. Loss of over ten percent of total body water can cause physical and mental deterioration, accompanied by severe thirst. Death occurs at a loss of between fifteen and twenty-five percent of the body water.Ashcroft F, Life Without Water in Life at the Extremes. Berkeley and Los Angeles, 2000, 134-138. Mild dehydration is characterized by thirst and general discomfort and is usually resolved with oral rehydration. Dehydration can cause hypernatremia (high levels of sodium ...
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Finger
A finger is a limb of the body and a type of digit, an organ of manipulation and sensation found in the hands of most of the Tetrapods, so also with humans and other primates. Most land vertebrates have five fingers ( Pentadactyly). Chambers 1998 p. 603 Oxford Illustrated pp. 311, 380 Land vertebrate fingers The five-rayed anterior limbs of terrestrial vertebrates can be derived phylogenetically from the pectoral fins of fish. Within the taxa of the terrestrial vertebrates, the basic pentadactyl plan, and thus also the fingers and phalanges, undergo many variations. Morphologically the different fingers of terrestrial vertebrates are homolog. The wings of birds and those of bats are not homologous, they are analogue flight organs. However, the phalanges within them are homologous. Chimpanzees have lower limbs that are specialized for manipulation, and (arguably) have fingers on their lower limbs as well. In the case of Primates in general, the digits of the hand a ...
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Vertebrate
Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, with currently about 69,963 species described. Vertebrates comprise such groups as the following: * jawless fish, which include hagfish and lampreys * jawed vertebrates, which include: ** cartilaginous fish (sharks, rays, and ratfish) ** bony vertebrates, which include: *** ray-fins (the majority of living bony fish) *** lobe-fins, which include: **** coelacanths and lungfish **** tetrapods (limbed vertebrates) Extant vertebrates range in size from the frog species ''Paedophryne amauensis'', at as little as , to the blue whale, at up to . Vertebrates make up less than five percent of all described animal species; the rest are invertebrates, which lack vertebral columns. The vertebrates traditionally include the hagfish, which do no ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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Hereditary
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents. Through heredity, variations between individuals can accumulate and cause species to evolve by natural selection. The study of heredity in biology is genetics. Overview In humans, eye color is an example of an inherited characteristic: an individual might inherit the "brown-eye trait" from one of the parents. Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype. The complete set of observable traits of the structure and behavior of an organism is called its phenotype. These traits arise from the interaction of its genotype with the environment. As a result, many aspects of an organism's phenotype are not inherited. For example, suntanned skin ...
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