Electron Microscope
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Electron Microscope
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a higher resolving power than light microscopes and can reveal the structure of smaller objects. A scanning transmission electron microscope has achieved better than 50  pm resolution in annular dark-field imaging mode and magnifications of up to about 10,000,000× whereas most light microscopes are limited by diffraction to about 200  nm resolution and useful magnifications below 2000×. Electron microscopes use shaped magnetic fields to form electron optical lens systems that are analogous to the glass lenses of an optical light microscope. Electron microscopes are used to investigate the ultrastructure of a wide range of biological and inorganic specimens including microorganisms, cells, large molecules, biopsy samples, ...
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Electron Microscope
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a higher resolving power than light microscopes and can reveal the structure of smaller objects. A scanning transmission electron microscope has achieved better than 50  pm resolution in annular dark-field imaging mode and magnifications of up to about 10,000,000× whereas most light microscopes are limited by diffraction to about 200  nm resolution and useful magnifications below 2000×. Electron microscopes use shaped magnetic fields to form electron optical lens systems that are analogous to the glass lenses of an optical light microscope. Electron microscopes are used to investigate the ultrastructure of a wide range of biological and inorganic specimens including microorganisms, cells, large molecules, biopsy samples, ...
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Cell (biology)
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body
in Chapter 21 of
Molecular Biology of the Cell
'' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos. It is also common to describe small molecules such as ...
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Max Knoll
Max Knoll (17 July 1897 – 6 November 1969) was a German electrical engineer. Knoll was born in Wiesbaden and studied in Munich and at the Technical University of Berlin, where he obtained his doctorate A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''l ... in the Institute for High Voltage Technology. In 1927 he became the leader of the electron research group there, where he and his co-worker, Ernst Ruska, invented the electron microscope in 1931. In April 1932, Knoll joined Telefunken in Berlin to do developmental work in the field of television design. He was also a private lecturer in Berlin. After World War II, Knoll joined the University of Munich as extraordinary professor and director of the Institute for Electromedicine. He moved to the United States, USA in 1948, to wo ...
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Ernst Ruska
Ernst August Friedrich Ruska (; 25 December 1906 – 27 May 1988) was a German physicist who won the Nobel Prize in Physics in 1986 for his work in electron optics, including the design of the first electron microscope. Life and career Ernst Ruska was born in Heidelberg, Germany. He was educated at the Technical University of Munich from 1925 to 1927 and then entered the Technical University of Berlin, where he posited that microscopes using electrons, with wavelengths 1000 times shorter than those of light, could provide a more detailed picture of an object than a microscope utilizing light, in which magnification is limited by the size of the wavelengths. In 1931, he demonstrated that a magnetic coil could act as an electron lens, and used several coils in a series to build the first electron microscope in 1933. After completing his PhD in 1933, Ruska continued to work in the field of electron optics, first at Fernseh AG in Berlin-Zehlendorf, and then from 1937 at Siemens ...
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Leo Szilard
Leo Szilard (; hu, Szilárd Leó, pronounced ; born Leó Spitz; February 11, 1898 – May 30, 1964) was a Hungarian-German-American physicist and inventor. He conceived the nuclear chain reaction in 1933, patented the idea of a nuclear fission reactor in 1934, and in late 1939 wrote the letter for Albert Einstein's signature that resulted in the Manhattan Project that built the atomic bomb. According to György Marx, he was one of the Hungarian scientists known as The Martians. Szilard initially attended Palatine Joseph Technical University in Budapest, but his engineering studies were interrupted by service in the Austro-Hungarian Army during World War I. He left Hungary for Germany in 1919, enrolling at Technische Hochschule (Institute of Technology) in Berlin-Charlottenburg, but became bored with engineering and transferred to Friedrich Wilhelm University, where he studied physics. He wrote his doctoral thesis on Maxwell's demon, a long-standing puzzle in the ph ...
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Dennis Gabor
Dennis Gabor ( ; hu, Gábor Dénes, ; 5 June 1900 – 9 February 1979) was a Hungarian-British electrical engineer and physicist, most notable for inventing holography, for which he later received the 1971 Nobel Prize in Physics. He obtained British citizenship in 1934, and spent most of his life in England. Life and career Gabor was born as Günszberg Dénes, into a Jewish family in Budapest, Hungary. In 1918, his family converted to Lutheranism. Dennis was the first-born son of Günszberg Bernát and Jakobovits Adél. Despite having a religious background, religion played a minor role in his later life and he considered himself agnostic. In 1902, the family received permission to change their surname from Günszberg to Gábor. He served with the Hungarian artillery in northern Italy during World War I. He began his studies in engineering at the Technical University of Budapest in 1918, later in Germany, at the Charlottenburg Technical University in Berlin, now known as t ...
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Hans Busch
Hans Walter Hugo Busch (27 February 1884 in Jüchen, North Rhine-Westphalia, Germany – 16 February 1973 in Darmstadt, Hesse) was a German physicist. He was a pioneer of electron optics and laid the theoretical basis for the electron microscope. From 1904 to 1905 he studied physics in Strasbourg, from 1905 to 1906 in Berlin and from 1907 to 1911 physics and applied physics in Göttingen. He then was assistant for applied electrical engineering in Göttingen. He received his doctorate in 1911 from the University of Göttingen. In 1920 he habilitated from the same university and was then Privatdozent of physics and applied physics. In 1921 he was Privatdozent in Jena. In 1922 he became associate professor in Jena. In 1929 he became professor at the Technical University of Berlin. In 1930 he became Professor in Electrical Engineering at the Technische Hochschule Darmstadt (TH Darmstadt) and from 1933 to 1934 the rector of the university. From 1937 to 1939 and 1944 to 1947 he was ...
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Electron Interaction With Matter
The electron ( or ) is a subatomic particle with a negative one elementary electric charge. Electrons belong to the first generation of the lepton particle family, and are generally thought to be elementary particles because they have no known components or substructure. The electron's mass is approximately 1/1836 that of the proton. Quantum mechanical properties of the electron include an intrinsic angular momentum (spin) of a half-integer value, expressed in units of the reduced Planck constant, . Being fermions, no two electrons can occupy the same quantum state, in accordance with the Pauli exclusion principle. Like all elementary particles, electrons exhibit properties of both particles and waves: They can collide with other particles and can be diffracted like light. The wave properties of electrons are easier to observe with experiments than those of other particles like neutrons and protons because electrons have a lower mass and hence a longer de Broglie wavelength ...
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Frame Grabber
A frame grabber is an electronic device that captures (i.e., "grabs") individual, digital still frames from an analog video signal or a digital video stream. It is usually employed as a component of a computer vision system, in which video frames are captured in digital form and then displayed, stored, transmitted, analyzed, or combinations of these. Historically, frame grabber expansion cards were the predominant way to interface cameras to PCs. Other interface methods have emerged since then, with frame grabbers (and in some cases, cameras with built-in frame grabbers) connecting to computers via interfaces such as USB, Ethernet and IEEE 1394 ("FireWire"). Early frame grabbers typically had only enough memory to store a single digitized video frame, whereas many modern frame grabbers can store multiple frames. Modern frame grabbers often are able to perform functions beyond capturing a single video input. For example, some devices capture audio in addition to video, and some d ...
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Micrograph
A micrograph or photomicrograph is a photograph or digital image taken through a microscope or similar device to show a magnified image of an object. This is opposed to a macrograph or photomacrograph, an image which is also taken on a microscope but is only slightly magnified, usually less than 10 times. Micrography is the practice or art of using microscopes to make photographs. A micrograph contains extensive details of microstructure. A wealth of information can be obtained from a simple micrograph like behavior of the material under different conditions, the phases found in the system, failure analysis, grain size estimation, elemental analysis and so on. Micrographs are widely used in all fields of microscopy. Types Photomicrograph A light micrograph or photomicrograph is a micrograph prepared using an optical microscope, a process referred to as ''photomicroscopy''. At a basic level, photomicroscopy may be performed simply by connecting a camera to a microscope, th ...
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Failure Analysis
Failure analysis is the process of collecting and analyzing data to determine the cause of a failure, often with the goal of determining corrective actions or liability. According to Bloch and Geitner, ”machinery failures reveal a reaction chain of cause and effect… usually a deficiency commonly referred to as the symptom…”. failure analysis can save money, lives, and resources if done correctly and acted upon. It is an important discipline in many branches of manufacturing industry, such as the electronics industry, where it is a vital tool used in the development of new products and for the improvement of existing products. The failure analysis process relies on collecting failed components for subsequent examination of the cause or causes of failure using a wide array of methods, especially microscopy and spectroscopy. Nondestructive testing (NDT) methods (such as industrial computed tomography scanning) are valuable because the failed products are unaffected by analysis, ...
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Crystalline
A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macroscopic single crystals are usually identifiable by their geometrical shape, consisting of flat faces with specific, characteristic orientations. The scientific study of crystals and crystal formation is known as crystallography. The process of crystal formation via mechanisms of crystal growth is called crystallization or solidification. The word ''crystal'' derives from the Ancient Greek word (), meaning both "ice" and "rock crystal", from (), "icy cold, frost". Examples of large crystals include snowflakes, diamonds, and table salt. Most inorganic solids are not crystals but polycrystals, i.e. many microscopic crystals fused together into a single solid. Polycrystals include most metals, rocks, ceramics, and ice. A third category of s ...
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