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Encephalitozoonosis
Encephalitozoonosis is a parasitic disease caused by the protozoan ''Encephalitozoon cuniculi'', which mainly affects rabbits in Europe. Other Strain (biology), strains of the pathogen cause disease in Murinae, Old World mice and Canidae, canines. Encephalitozoonosis occurs mainly in immunocompromised animals and is a potential zoonosis. Although very rare, it can also occur in immunocompromised humans. Wright and Craighead first described the disease in 1922. The pathogen primarily affects the kidneys and brain, causing Neurological disorder, neurological disorders. The most common symptom is a tilted head. Fenbendazole, an antiparasitic drug, can be used to combat the pathogen and prevent new infections. If clinical symptoms occur, treatment must be extended by administering antibiotics and supportive measures. The prospects of recovery are uncertain. Pathogen and occurrence ''Encephalitozoon cuniculi'' is a microsporidian protozoan that is an obligate intracellular parasite. It ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Encephalitozoon Cuniculi
''Encephalitozoon cuniculi'' (''E. cuniculi'') is a mammalian microsporidial pathogen with world-wide distribution. An important cause of neurologic and renal disease in rabbits, ''E. cuniculi'' can also cause disease in immunocompromised people. Classification and cell structure ''E. cuniculi'' is a spore-forming unicellular parasite belonging to the phylum Microsporidia. Microsporidia are obligate intracellular parasitic fungi infecting many animal groups. Lacking mitochondria and peroxysomes, these unicellular eukaryotes were first considered a deeply branching protist lineage that diverged before the endosymbiotic event that led to mitochondria. The discovery of a gene for a mitochondrial-type chaperone combined with molecular phylogenetic data later implied that microsporidia are atypical fungi that lost mitochondria during evolution. Genome The genome consists of approximately 2.9-megabases (Mbs) in 11 chromosomes, with a total of 1,997 potential protein-coding genes. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
