Doramectin
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Doramectin
Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle. It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Similarly to other drugs of this family, it is produced by fermentation by selected strains of ''Streptomyces avermitilis''. Its spectrum includes: ''Haemonchus, Ostertagia, Trichostrongylus, Cooperia'', and ''Oesophagostomum'' species and ''Dictyocaulus viviparus'', ''Dermatobia hominis, Boophilus microplus'', and ''Psoroptes bovis'', among many other internal and external parasites. It is available as an injection and as a 5-mg/ml topical solution. Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufacture ...
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Veterinary Drug
An animal drug (also veterinary drug) refers to a drug intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in animals. Regulation United States The U.S. Food and Drug Administration (FDA) has the broad mandate under the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 321 et seq.) to assure the safety and effectiveness of animal drugs and their use in all animals, including farm animals. The division of the FDA responsible for this is the Center for Veterinary Medicine (CVM). The equivalents of the Investigational New Drug and New Drug Application are known as the Investigational New Animal Drug and New Animal Drug Application, respectively. Before CVM formally approves an animal drug, the sponsor or manufacturer of the drug must document in scientific testing that the drug has been found "safe and effective". The testing data also must demonstrate that a methodology is available to detect and measure any residue left in edible animal produ ...
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Oesophagostomum
''Oesophagostomum'' is a genus of parasitic nematodes (roundworms) of the family Strongylidae. These worms occur in Africa, Brazil, China, Indonesia and the Philippines. The majority of human infection with ''Oesophagostomum'' is localized to northern Togo and Ghana. Because the eggs may be indistinguishable from those of the hookworms (which are widely distributed and can also rarely cause helminthomas), the species causing human helminthomas are rarely identified with accuracy. ''Oesophagostomum'', especially ''O. bifurcum'', are common parasites of livestock and animals like goats, pigs and non-human primates, although it seems that humans are increasingly becoming favorable hosts as well. The disease they cause, oesophagostomiasis, is known for the nodule formation it causes in the intestines of its infected hosts, which can lead to more serious problems such as dysentery. Although the routes of human infection have yet to be elucidated sufficiently, it is believed that transm ...
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Horse
The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million years from a small multi-toed creature, ''Eohippus'', into the large, single-toed animal of today. Humans began domesticating horses around 4000 BCE, and their domestication is believed to have been widespread by 3000 BCE. Horses in the subspecies ''caballus'' are domesticated, although some domesticated populations live in the wild as feral horses. These feral populations are not true wild horses, as this term is used to describe horses that have never been domesticated. There is an extensive, specialized vocabulary used to describe equine-related concepts, covering everything from anatomy to life stages, size, colors, markings, breeds, locomotion, and behavior. Horses are adapted to run, allowing them to quickly escape predators, and po ...
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Sheep
Sheep or domestic sheep (''Ovis aries'') are domesticated, ruminant mammals typically kept as livestock. Although the term ''sheep'' can apply to other species in the genus ''Ovis'', in everyday usage it almost always refers to domesticated sheep. Like all ruminants, sheep are members of the order Artiodactyla, the even-toed ungulates. Numbering a little over one billion, domestic sheep are also the most numerous species of sheep. An adult female is referred to as a ''ewe'' (), an intact male as a ''ram'', occasionally a ''tup'', a castrated male as a ''wether'', and a young sheep as a ''lamb''. Sheep are most likely descended from the wild mouflon of Europe and Asia, with Iran being a geographic envelope of the domestication center. One of the earliest animals to be domesticated for agricultural purposes, sheep are raised for fleeces, meat (lamb, hogget or mutton) and milk. A sheep's wool is the most widely used animal fiber, and is usually harvested by shearing. In Commonw ...
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Cattle
Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult males are referred to as bulls. Cattle are commonly raised as livestock for meat (beef or veal, see beef cattle), for milk (see dairy cattle), and for hides, which are used to make leather. They are used as riding animals and draft animals ( oxen or bullocks, which pull carts, plows and other implements). Another product of cattle is their dung, which can be used to create manure or fuel. In some regions, such as parts of India, cattle have significant religious significance. Cattle, mostly small breeds such as the Miniature Zebu, are also kept as pets. Different types of cattle are common to different geographic areas. Taurine cattle are found primarily in Europe and temperate areas of Asia, the Americas, and Australia. Zebus (also ...
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Topical
A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. Many topical medications are epicutaneous, meaning that they are applied directly to the skin. Topical medications may also be inhalational, such as asthma medications, or applied to the surface of tissues other than the skin, such as eye drops applied to the conjunctiva, or ear drops placed in the ear, or medications applied to the surface of a tooth. The word ''topical'' derives from Greek τοπικός ''topikos'', "of a place". Justification Topical drug delivery is a route of administering drugs via the skin to provide topical therapeutic effects. As skin is one of the largest and most superficial organs in the human body, pharmacists utilise it to deliver various drugs. This ...
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Injection (medicine)
An injection (often and usually referred to as a "shot" in US English, a "jab" in UK English, or a "jag" in Scottish English and Scots) is the act of administering a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe. An injection is considered a form of parenteral drug administration; it does not involve absorption in the digestive tract. This allows the medication to be absorbed more rapidly and avoid the first pass effect. There are many types of injection, which are generally named after the body tissue the injection is administered into. This includes common injections such as subcutaneous, intramuscular, and intravenous injections, as well as less common injections such as intraperitoneal, intraosseous, intracardiac, intraarticular, and intracavernous injections. Injections are among the most common health care procedures, with at least 16 billion administered in developing and transitional countries each yea ...
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Psoroptes Bovis
''Psoroptes'' is a genus of mites, including the agents that cause psoroptic mange. Psoroptic mange ''Psoroptes'' mites are responsible for causing psoroptic mange in various animals, leading to economic losses among farmers of cattle, sheep and goats. It is also known as sheep scab and cattle scab. The disease is highly infectious, and is transmitted via fenceposts and other structures that livestock use when scratching themselves. The mites have mouthparts which do not pierce the skin, but are adapted to feeding on the surface, where the mites abrade the stratum corneum. See Mites of livestock Mites are small crawling animals related to ticks and spiders. Most mites are free-living and harmless. Other mites are parasitic, and those that infest livestock animals cause many diseases that are widespread, reduce production and profit for f ... for photographs of infestations by ''Psoroptes''. Taxonomy ''Psoroptes'' has been traditionally considered to include five species ...
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Boophilus Microplus
The Asian blue tick (''Rhipicephalus'' (''Boophilus'') ''microplus'', ''Rhipicephalus microplus'', or ''Boophilus microplus'') is an economically important tick that parasitises a variety of livestock species especially cattle, on which it is the most economically significant ectoparasite in the world. It is known as the Australian cattle tick, southern cattle tick, Cuban tick, Madagascar blue tick, and Puerto Rican Texas fever tick. It is classified as a hard tick in the family Ixodidae. It is a small teardrop-shaped arachnid with a hardened plate called the scutum covering its head. Males are entirely covered in scutum on their backs with additional plates called festoons along their sides. The body can be brown or pale in nymphs and darkens as the tick matures. Adults have 8 cream-colored legs.Spickler, Anna Rovid. 2022. ''Rhipicephalus'' (''Boophilus'') ''microplus''. Retrieved from http://www.cfsph.iastate.edu/ DiseaseInfo/factsheets.php. In ''R. microplus'' the hypostome h ...
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Dermatobia Hominis
The human botfly, ''Dermatobia hominis'' (Greek δέρμα, skin + βίος, life, and Latin '' hominis'', of a human), is a species of botfly whose larvae parasitise humans (in addition to a wide range of other animals, including other primates). It is also known as the torsalo or American warble fly, though the warble fly is in the genus ''Hypoderma'' and not ''Dermatobia'', and is a parasite on cattle and deer instead of humans. ''Dermatobia'' fly eggs have been shown to be vectored by over 40 species of mosquitoes and muscoid flies, as well as one species of tick; the female captures the mosquito and attaches its eggs to its body, then releases it. Either the eggs hatch while the mosquito is feeding and the larvae use the mosquito bite area as the entry point, or the eggs simply drop off the muscoid fly when it lands on the skin. The larvae develop inside the subcutaneous layers, and after about eight weeks, they drop out to pupate for at least a week, typically in the so ...
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Dictyocaulus Viviparus
''Dictyocaulus viviparus'' is a species of nematodes belonging to the family Dictyocaulidae. The species has cosmopolitan distribution In biogeography, cosmopolitan distribution is the term for the range of a taxon that extends across all or most of the world in appropriate habitats. Such a taxon, usually a species, is said to exhibit cosmopolitanism or cosmopolitism. The ext .... It is parasitic, and has the common name of the bovine lungworm due to its negative impact on cattle. References Strongylida Nematodes described in 1782 Parasitic nematodes of mammals {{Rhabditida-stub ...
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