Doramectin (Dectomax) is a

veterinary drug An animal drug (also veterinary drug) refers to a pharmaceutical drug, drug intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in animals. Regulation United States The U.S. Food and Drug Administration (FDA) ...

approved by the

Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...

(FDA) for the treatment of parasites such as gastrointestinal

roundworm The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a bro ...

lungworm Lungworms are parasitic nematode worms of the order Strongylida that infest the lungs of vertebrates. The name is used for a variety of different groups of nematodes, some of which also have other common names; what they have in common is that t ...

eyeworm ''Thelazia'' is a genus of nematode worms which parasitize the eyes and associated tissues of various bird and mammal hosts, including humans. They are often called "eyeworms", and infestation with ''Thelazia'' species is referred to as "thelaz ...

grub Grub can refer to Grub (larva), of the beetle superfamily Scarabaeoidea, or as a slang term for food. It can also refer to: Places * Grub, Appenzell Ausserrhoden, Switzerland * Grub, St. Gallen, Switzerland * Grub (Amerang), a hamlet in Bavar ...

s, sucking lice and

mange mite Mange is a type of skin disease caused by parasitic mites. Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection ...

s in cattle. It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of

ivermectin Ivermectin (, '' EYE-vər-MEK-tin'') is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. Approved for human use in 1987, today it is used to treat i ...

. Similarly to other drugs of this family, it is produced by fermentation by selected strains of ''

Streptomyces avermitilis ''Streptomyces avermitilis'' is a species of bacteria in the genus ''Streptomyces''. This bacterium was discovered by Satoshi Ōmura in Shizuoka Prefecture, Japan. The first complete genome sequence of ''S. avermitilis'' was completed in 2003. ...

''. Its spectrum includes: ''

Haemonchus ''Haemonchus'' is a genus of nematodes belonging to the family Trichostrongylidae. They are abomasal parasites that cause anemia, followed by white eye disease. The genus has cosmopolitan distribution. Species: *''Haemonchus contortus '' ...

Ostertagia ''Ostertagia'' is a genus of nematodes belonging to the family Trichostrongylidae. The genus has cosmopolitan distribution. Species: *'' Ostertagia antipini'' *'' Ostertagia arctica'' *'' Ostertagia buriatica'' *'' Ostertagia dahurica'' *' ...

Trichostrongylus ''Trichostrongylus'' species are nematodes (round worms), which are ubiquitous among herbivores worldwide, including cattle, sheep, donkeys, goats, deer, and rabbits.Garcia LS, editor. Diagnostic Medical Parasitology. 5 ed. Washington, DC: ASM Pr ...

, Cooperia'', and ''

Oesophagostomum ''Oesophagostomum'' is a genus of parasitic nematodes (roundworms) of the family Strongylidae. These worms occur in Africa, Brazil, China, Indonesia and the Philippines. The majority of human infection with ''Oesophagostomum'' is localized to no ...

'' species and ''

Dictyocaulus viviparus ''Dictyocaulus viviparus'' is a species of nematodes belonging to the family Dictyocaulidae. The species has cosmopolitan distribution In biogeography, cosmopolitan distribution is the term for the range of a taxon that extends across all ...

'', ''

Dermatobia hominis The human botfly, ''Dermatobia hominis'' (Greek δέρμα, skin + βίος, life, and Latin '' hominis'', of a human), is a species of botfly whose larvae parasitise humans (in addition to a wide range of other animals, including other primates ...

Boophilus microplus The Asian blue tick (''Rhipicephalus'' (''Boophilus'') ''microplus'', ''Rhipicephalus microplus'', or ''Boophilus microplus'') is an economically important tick that parasitises a variety of livestock species especially cattle, on which it is th ...

'', and ''

Psoroptes bovis ''Psoroptes'' is a genus of mites, including the agents that cause psoroptic mange. Psoroptic mange ''Psoroptes'' mites are responsible for causing psoroptic mange in various animals, leading to economic losses among farmers of cattle, sheep ...

'', among many other internal and external parasites. It is available as an

injection Injection or injected may refer to: Science and technology * Injective function, a mathematical function mapping distinct arguments to distinct values * Injection (medicine), insertion of liquid into the body with a syringe * Injection, in broadca ...

and as a 5-mg/ml

topical A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes ...

solution. Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufactured by Agrovet Market Animal Health) in a 1% Doramectin Long Acting Injectable Solution for

cattle Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult ma ...

sheep Sheep or domestic sheep (''Ovis aries'') are domesticated, ruminant mammals typically kept as livestock. Although the term ''sheep'' can apply to other species in the genus '' Ovis'', in everyday usage it almost always refers to domesticated ...

, swineAgrovet Market Animal Health
/ref> and others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation, extending its action up to 42 days. Doramectin is also available for

horse The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 million yea ...

s as an oral, flavored, bioadhesive gel under the name Doraquest L.A. Oral Gel.Agrovet Market Animal Health-Doraquest L.A. Oral Gel
/ref> It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.

References

{{Endectocides Anthelmintics Veterinary drugs