Dibenzoxazepine
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Dibenzoxazepine
CR gas or dibenzoxazepine (chemical name dibenz 'b'',''f''1,4]oxazepine, is an incapacitating agent and a lachrymatory agent. CR was developed by the British Ministry of Defence as a riot control agent in the late 1950s and early 1960s. A report from the Porton Down laboratories described exposure as "like being thrown blindfolded into a bed of stinging nettles", and it earned the nickname "firegas". In its effects, the CR gas is very similar (but twice as potent) to o-chlorobenzylidene malononitrile CS gas, even though there is little structural resemblance between the two. For example, 2 mg of dry CR cause skin redness in 10 min, 5 mg cause burning and erythremia, 20 mg- strong pain. Water usually amplifies the pain effect of CR on skin. CR aerosols cause irritation as 0.0002 mg/L, which becomes intolerable at 0.003 mg/L. The lethal dose of CR through air inhalation is LD50 = 350 mg·min/L. Physical properties and deployment CR is a pale yellow ...
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Loxapine
Loxapine, sold under the brand names Loxitane and Adasuve (''inhalation'' only) among others, is an antipsychotic medication used primarily in the treatment of schizophrenia. The medicine is a member of the dibenzoxazepine class and structurally very similar to clozapine. Several researchers have argued that loxapine, initially classified as a typical antipsychotic, behaves as an atypical antipsychotic. Loxapine may be metabolized by ''N''-demethylation to amoxapine, a tricyclic antidepressant. Medical uses The US Food and Drug Administration (FDA) has approved loxapine inhalation powder for the acute treatment of agitation associated with schizophrenia or bipolar I disorder in adults. A brief review of loxapine found no conclusive evidence that it was particularly effective in patients with schizophrenia. A subsequent systematic review considered that the limited evidence did not indicate a clear difference in its effects from other antipsychotics. Available forms Loxapine ...
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Oxazepine
Oxazepines are a family of unsaturated heterocycles containing seven atoms, with a nitrogen replacing a carbon at one position and with an oxygen replacing a carbon at one position. See also * Azepine * Benzazepines * Diazepine * Oxepin * Borepin * CR gas CR gas or dibenzoxazepine (chemical name dibenz 'b'',''f''1,4]oxazepine, is an incapacitating agent and a lachrymatory agent. CR was developed by the British Ministry of Defence as a riot control agent in the late 1950s and early 1960s. A report ... (dibenzoxazepine) References Oxazepines, {{Heterocyclic-stub ...
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Incapacitating Agent
The term incapacitating agent is defined by the United States Department of Defense as: :"An agent that produces temporary physiological or mental effects, or both, which will render individuals incapable of concerted effort in the performance of their assigned duties." It describes an agent which renders a person unable to harm themselves or others, regardless of consciousness. Lethal agents are primarily intended to kill, but incapacitating agents can also kill if administered in a potent enough dose, or in certain scenarios. The term "incapacitation," when used in a general sense, is not equivalent to the term "disability" as used in occupational medicine and denotes the inability to perform a task because of a quantifiable physical or mental impairment. In this sense, any of the chemical warfare agents may incapacitate a victim; however, by the military definition of this type of agent, incapacitation refers to impairments that are temporary and nonlethal. Thus, riot-contr ...
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Carcinogen
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis (the formation of cancer). This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes. Several radioactive substances are considered carcinogens, but their carcinogenic activity is attributed to the radiation, for example gamma rays and alpha particles, which they emit. Common examples of non-radioactive carcinogens are inhaled asbestos, certain dioxins, and tobacco smoke. Although the public generally associates carcinogenicity with synthetic chemicals, it is equally likely to arise from both natural and synthetic substances. Carcinogens are not necessarily immediately toxic; thus, their effect can be insidious. Carcinogens, as mentioned, are agents in the environment capable of contributing to cancer growth. Carcinogens can be categorized into two different types: activation-dependent and activation-independent, and each nature impacts their level ...
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Lachrymatory Agents
Lachrymatory or lacrymatory may refer to: * Something that has the effect of ''lachrymation'', causing the secretion of tears * Tear gas Tear gas, also known as a lachrymator agent or lachrymator (), sometimes colloquially known as "mace" after the early commercial aerosol, is a chemical weapon that stimulates the nerves of the lacrimal gland in the eye to produce tears. In ad ..., known formally as a ''lachrymatory agent'' or ''lachrymator'' * A lacrymatory, a small vessel of terracotta or glass found in Roman and late Greek tombs, thought to have been used to collect the tears of mourners at funerals {{disambiguation ...
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Tear Gas
Tear gas, also known as a lachrymator agent or lachrymator (), sometimes colloquially known as "mace" after the early commercial aerosol, is a chemical weapon that stimulates the nerves of the lacrimal gland in the eye to produce tears. In addition, it can cause severe eye and respiratory pain, skin irritation, bleeding, and blindness. Common lachrymators both currently and formerly used as tear gas include pepper spray (OC gas), PAVA spray (nonivamide), CS gas, CR gas, CN gas (phenacyl chloride), bromoacetone, xylyl bromide and Mace (a branded mixture). While lachrymatory agents are commonly deployed for riot control by law enforcement and military personnel, its use in warfare is prohibited by various international treaties.E.g. the Geneva Protocol of 1925 prohibited the use of "asphyxiating gas, or any other kind of gas, liquids, substances or similar materials". During World War I, increasingly toxic and deadly lachrymatory agents were used. The short and long-term effec ...
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Pepper Spray
Pepper spray, oleoresin capsicum spray, OC spray, capsaicin spray, or capsicum spray is a lachrymatory agent (a compound that irritates the eyes to cause a burning sensation, pain, and temporary blindness) used in policing, riot control, crowd control, and self-defense, including defense against dogs and bears. Its inflammatory effects cause the eyes to close, temporarily taking away vision. This temporary blindness allows officers to more easily restrain subjects and permits people in danger to use pepper spray in self-defense for an opportunity to escape. It also causes temporary discomfort and burning of the lungs which causes shortness of breath. Pepper spray was engineered into a spray originally for defense against bears, mountain lions, wolves and other dangerous predators, and is often referred to colloquially as bear spray. Kamran Loghman, the person who developed it for use in riot control, wrote the guide for police departments on how it should be used. It was s ...
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2013 Protests In Turkey
A wave of demonstrations and civil unrest in Turkey began on 28 May 2013, initially to contest the urban development plan for Istanbul's Taksim Gezi Park. The protests were sparked by outrage at the violent eviction of a sit-in at the park protesting the plan. Subsequently, supporting protests and strikes took place across Turkey, protesting against a wide range of concerns at the core of which were issues of freedom of the press, of expression and of assembly, as well as the alleged political Islamist government's erosion of Turkey's secularism. With no centralised leadership beyond the small assembly that organised the original environmental protest, the protests have been compared to the Occupy movement and the May 1968 events. Social media played a key part in the protests, not least because much of the Turkish media downplayed the protests, particularly in the early stages. Three and a half million people (out of Turkey's population of 80 million) are estimated to have tak ...
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South Africa
South Africa, officially the Republic of South Africa (RSA), is the southernmost country in Africa. It is bounded to the south by of coastline that stretch along the South Atlantic and Indian Oceans; to the north by the neighbouring countries of Namibia, Botswana, and Zimbabwe; and to the east and northeast by Mozambique and Eswatini. It also completely enclaves the country Lesotho. It is the southernmost country on the mainland of the Old World, and the second-most populous country located entirely south of the equator, after Tanzania. South Africa is a biodiversity hotspot, with unique biomes, plant and animal life. With over 60 million people, the country is the world's 24th-most populous nation and covers an area of . South Africa has three capital cities, with the executive, judicial and legislative branches of government based in Pretoria, Bloemfontein, and Cape Town respectively. The largest city is Johannesburg. About 80% of the population are Black South Afri ...
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Human Rights Watch
Human Rights Watch (HRW) is an international non-governmental organization, headquartered in New York City, that conducts research and advocacy on human rights. The group pressures governments, policy makers, companies, and individual human rights abusers to denounce abuse and respect human rights, and the group often works on behalf of refugees, children, migrants, and political prisoners. Human Rights Watch, in 1997, shared the Nobel Peace Prize as a founding member of the International Campaign to Ban Landmines, and it played a leading role in the 2008 treaty banning cluster munitions. The organization's annual expenses totaled $50.6 million in 2011, $69.2 million in 2014, and $75.5 million in 2017. History Human Rights Watch was co-founded by Robert L. Bernstein Jeri Laber and Aryeh Neier as a private American NGO in 1978, under the name Helsinki Watch, to monitor the then-Soviet Union's compliance with the Helsinki Accords. Helsinki Watch adopted a practice of public ...
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Mohammed ElBaradei
Mohamed Mustafa ElBaradei ( ar, محمد مصطفى البرادعي, Muḥammad Muṣṭafá al-Barādaʿī, ; born 17 June 1942) is an Egyptian law scholar and diplomat who served as the vice president of Egypt on an interim basis from 14 July 2013 until his resignation on 14 August 2013. He was the Director General of the International Atomic Energy Agency (IAEA), an intergovernmental organization under the auspices of the United Nations, from 1997 to 2009. He and the IAEA were jointly awarded the Nobel Peace Prize in 2005 "for their efforts to prevent nuclear energy from being used for military purposes and to ensure that nuclear energy for peaceful purposes is used in the safest possible way". ElBaradei was also featured in the Western press regarding recent politics in Egypt, particularly the 2011 revolution which ousted President Hosni Mubarak and the 2013 Egyptian coup d'état. Family and personal life ElBaradei was born and raised in Giza Governorate, Greater Cairo, E ...
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2011 Egyptian Revolution
The 2011 Egyptian revolution, also known as the 25 January revolution ( ar, ثورة ٢٥ يناير; ), began on 25 January 2011 and spread across Egypt. The date was set by various youth groups to coincide with the annual Egyptian "Police holiday" as a statement against increasing police brutality during the last few years of Hosni Mubarak's presidency. It consisted of demonstrations, marches, occupations of plazas, non-violent civil resistance, acts of civil disobedience and strike action, strikes. Millions of protesters from a range of socio-economic and religious backgrounds demanded the overthrow of Egyptian President Hosni Mubarak. Violent clashes between security forces and protesters resulted in at least 846 people killed and over 6,000 injured. Protesters retaliated by burning over 90 police stations across the country. The Egyptian protesters' grievances focused on legal and political issues, including police brutality, state-of-emergency laws, lack of political free ...
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