Densitometry
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Densitometry
Densitometry is the quantitative measurement of optical density in light-sensitive materials, such as photographic paper or photographic film, due to exposure to light. Overview Optical density is a result of the darkness of a developed picture and can be expressed absolutely as the number of dark spots (i.e., silver grains in developed films) in a given area, but usually it is a relative value, expressed in a scale. Since density is usually measured by the decrease in the amount of light which shines through a transparent film, it is also called ''absorptiometry'', the measure of light absorption through the medium. The corresponding measuring device is called a densitometer (''absorptiometer''). The decadic (base-10) logarithm of the reciprocal of the transmittance is called the absorbance or ''density''. ''DMax'' and ''DMin'' refer to the maximum and minimum density that can be produced by the material. The difference between the two is the ''density range''. The density ra ...
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Dual-energy X-ray Absorptiometry
Dual-energy X-ray absorptiometry (DXA, or DEXA) is a means of measuring bone mineral density (BMD) using spectral imaging. Two X-ray beams, with different energy levels, are aimed at the patient's bones. When soft tissue absorption is subtracted out, the bone mineral density (BMD) can be determined from the absorption of each beam by bone. Dual-energy X-ray absorptiometry is the most widely used and most thoroughly studied bone density measurement technology. The DXA scan is typically used to diagnose and follow osteoporosis, as contrasted to the nuclear bone scan, which is sensitive to certain metabolic diseases of bones in which bones are attempting to heal from infections, fractures, or tumors. It is also sometimes used to assess body composition. Physics Soft tissue and bone have different attenuation coefficients to X-rays. A single X-ray beam passing through the body will be attenuated by both soft tissue and bone, and it is not possible to determine, from a single beam, ...
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Binary Logarithm
In mathematics, the binary logarithm () is the power to which the number must be raised to obtain the value . That is, for any real number , :x=\log_2 n \quad\Longleftrightarrow\quad 2^x=n. For example, the binary logarithm of is , the binary logarithm of is , the binary logarithm of is , and the binary logarithm of is . The binary logarithm is the logarithm to the base and is the inverse function of the power of two function. As well as , an alternative notation for the binary logarithm is (the notation preferred by ISO 31-11 and ISO 80000-2). Historically, the first application of binary logarithms was in music theory, by Leonhard Euler: the binary logarithm of a frequency ratio of two musical tones gives the number of octaves by which the tones differ. Binary logarithms can be used to calculate the length of the representation of a number in the binary numeral system, or the number of bits needed to encode a message in information theory. In computer ...
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Osteoporosis
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to bone fragility, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, and the hip. Until a broken bone occurs there are typically no symptoms. Bones may weaken to such a degree that a break may occur with minor stress or spontaneously. After the broken bone heals, the person may have chronic pain and a decreased ability to carry out normal activities. Osteoporosis may be due to lower-than-normal maximum bone mass and greater-than-normal bone loss. Bone loss increases after the menopause due to lower levels of estrogen, and after ' andropause' due to lower levels of testosterone. Osteoporosis may also occur due to a number of diseases or treatments, including alcoholism, anorexia, hyperthyroidism, ...
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Absorption (electromagnetic Radiation)
In physics, absorption of electromagnetic radiation is how matter (typically electrons bound in atoms) takes up a photon's energy — and so transforms electromagnetic energy into internal energy of the absorber (for example, thermal energy). A notable effect is attenuation, or the gradual reduction of the intensity of light waves as they propagate through a medium. Although the absorption of waves does not usually depend on their intensity (linear absorption), in certain conditions (optics) the medium's transparency changes by a factor that varies as a function of wave intensity, and saturable absorption (or nonlinear absorption) occurs. Quantifying absorption Many approaches can potentially quantify radiation absorption, with key examples following. * The absorption coefficient along with some closely related derived quantities * The attenuation coefficient (NB used infrequently with meaning synonymous with "absorption coefficient") * The Molar attenuation coefficient (a ...
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Measurement
Measurement is the quantification of attributes of an object or event, which can be used to compare with other objects or events. In other words, measurement is a process of determining how large or small a physical quantity is as compared to a basic reference quantity of the same kind. The scope and application of measurement are dependent on the context and discipline. In natural sciences and engineering, measurements do not apply to nominal properties of objects or events, which is consistent with the guidelines of the ''International vocabulary of metrology'' published by the International Bureau of Weights and Measures. However, in other fields such as statistics as well as the social and behavioural sciences, measurements can have multiple levels, which would include nominal, ordinal, interval and ratio scales. Measurement is a cornerstone of trade, science, technology and quantitative research in many disciplines. Historically, many measurement systems existed fo ...
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Diagnosis
Diagnosis is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines, with variations in the use of logic, analytics, and experience, to determine " cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions. Computer science and networking * Bayesian networks * Complex event processing * Diagnosis (artificial intelligence) * Event correlation * Fault management * Fault tree analysis * Grey problem * RPR Problem Diagnosis * Remote diagnostics * Root cause analysis * Troubleshooting * Unified Diagnostic Services Mathematics and logic * Bayesian probability * Block Hackam's dictum * Occam's razor * Regression diagnostics * Sutton's law copy right remover block Medicine * Medical diagnosis * Molecular diagnostics Methods * CDR Computerized Assessment System * Computer-assisted diagnosis * Differential diagnosis * Medical di ...
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Osteopenia
Osteopenia, known as "low bone mass" or "low bone density", is a condition in which bone mineral density is low. Because their bones are weaker, people with osteopenia may have a higher risk of fractures, and some people may go on to develop osteoporosis. In 2010, 43 million older adults in the US had osteopenia. Unlike osteoporosis, osteopenia does not usually cause symptoms, and losing bone density in itself does not cause pain. There is no single cause for osteopenia, although there are several risk factors, including modifiable (behavioral, including dietary and use of certain drugs) and non-modifiable (for instance, loss of bone mass with age). For people with risk factors, screening via a DXA scanner may help to detect the development and progression of low bone density. Prevention of low bone density may begin early in life and includes a healthy diet and weight-bearing exercise, as well as avoidance of tobacco and alcohol. The treatment of osteopenia is controversial: non-p ...
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Bone
A bone is a Stiffness, rigid Organ (biology), organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red blood cell, red and white blood cells, store minerals, provide structure and support for the body, and enable animal locomotion, mobility. Bones come in a variety of shapes and sizes and have complex internal and external structures. They are lightweight yet strong and hard and serve multiple Function (biology), functions. Bone tissue (osseous tissue), which is also called bone in the mass noun, uncountable sense of that word, is hard tissue, a type of specialized connective tissue. It has a honeycomb-like matrix (biology), matrix internally, which helps to give the bone rigidity. Bone tissue is made up of different types of bone cells. Osteoblasts and osteocytes are involved in the formation and mineralization (biology), mineralization of bone; osteoclasts are involved in the bone resorption, resor ...
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Calcium
Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to its heavier homologues strontium and barium. It is the fifth most abundant element in Earth's crust, and the third most abundant metal, after iron and aluminium. The most common calcium compound on Earth is calcium carbonate, found in limestone and the fossilised remnants of early sea life; gypsum, anhydrite, fluorite, and apatite are also sources of calcium. The name derives from Latin ''calx'' "lime", which was obtained from heating limestone. Some calcium compounds were known to the ancients, though their chemistry was unknown until the seventeenth century. Pure calcium was isolated in 1808 via electrolysis of its oxide by Humphry Davy, who named the element. Calcium compounds are widely used in many industries: in foods and pharma ...
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False-color
False color (or pseudo color) refers to a group of color rendering methods used to display images in color which were recorded in the visible or non-visible parts of the electromagnetic spectrum. A false-color image is an image that depicts an object in colors that differ from those a photograph (a true-color image) would show. In this image, colors have been assigned to three different wavelengths that our eyes cannot normally see. In addition, variants of ''false color'' such as pseudocolor, density slicing, and choropleths are used for information visualization of either data gathered by a single grayscale channel or data not depicting parts of the electromagnetic spectrum (e.g. elevation in relief maps or tissue types in magnetic resonance imaging). Types of color renderings True color The concept behind true color can help in understanding false color. An image is called a ''true-color'' image when it offers a natural color rendition, or when it comes close to it. ...
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Decibel
The decibel (symbol: dB) is a relative unit of measurement equal to one tenth of a bel (B). It expresses the ratio of two values of a power or root-power quantity on a logarithmic scale. Two signals whose levels differ by one decibel have a power ratio of 101/10 (approximately ) or root-power ratio of 10 (approximately ). The unit expresses a relative change or an absolute value. In the latter case, the numeric value expresses the ratio of a value to a fixed reference value; when used in this way, the unit symbol is often suffixed with letter codes that indicate the reference value. For example, for the reference value of 1 volt, a common suffix is " V" (e.g., "20 dBV"). Two principal types of scaling of the decibel are in common use. When expressing a power ratio, it is defined as ten times the logarithm in base 10. That is, a change in ''power'' by a factor of 10 corresponds to a 10 dB change in level. When expressing root-power quantities, a change in ''ampl ...
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Decadic Logarithm
In mathematics, the common logarithm is the logarithm with base 10. It is also known as the decadic logarithm and as the decimal logarithm, named after its base, or Briggsian logarithm, after Henry Briggs (mathematician), Henry Briggs, an English mathematician who pioneered its use, as well as standard logarithm. Historically, it was known as ''logarithmus decimalis'' or ''logarithmus decadis''. It is indicated by , , or sometimes with a capital (however, this notation is ambiguous, since it can also mean the complex natural logarithmic multi-valued function). On calculators, it is printed as "log", but mathematicians usually mean natural logarithm (logarithm with base e ≈ 2.71828) rather than common logarithm when they write "log". To mitigate this ambiguity, the ISO 80000-2, ISO 80000 specification recommends that should be written , and should be . Before the early 1970s, handheld electronic calculators were not available, and mechanical calculators capable of multiplica ...
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