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Dolichyl Diphosphate
Dolichyl, related to Dolichol, is used in the names of: * Dolichyl beta-D-glucosyl phosphate, a molecule involved in glycosylation *Dolichyl-diphosphate—polyphosphate phosphotransferase (EC 2.7.4.20) * Dolichyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.1.119) * Dolichyl-phosphatase (EC 3.1.3.51) * Dolichyl-phosphate alpha-N-acetylglucosaminyltransferase (EC 2.4.1.153) * Dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) * Dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) *Dolichyl-phosphate D-xylosyltransferase (EC 2.4.2.32) * Dolichyl-phosphate-mannose—glycolipid alpha-mannosyltransferase (EC 2.4.1.130) *Dolichyl-phosphate-mannose-protein mannosyltransferase (EC 2.4.1.109) * Dolichyl-xylosyl-phosphate—protein xylosyltransferase (EC 2.4.2.33) *UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase In enzymology, an UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase () is an enzyme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichol
Dolichol refers to any of a group of long-chain mostly unsaturated organic compounds that are made up of varying numbers of isoprene units terminating in an α-saturated isoprenoid group, containing an alcohol functional group. Functions Dolichols play a role in the co-translational modification of proteins known as ''N''-glycosylation in the form of dolichol phosphate. Dolichols function as a membrane anchor for the formation of the oligosaccharide Glc3-Man9-GlcNAc2 (where Glc is glucose, Man is mannose, and GlcNAc is ''N''-acetylglucosamine). This oligosaccharide is transferred from the dolichol donor onto certain asparagine residues (onto a specific sequence that is "Asn-X-Ser/Thr") of newly forming polypeptide chains. Dolichol is also involved in transfer of the monosaccharides to the forming Glc3-Man9-GlcNAc2-Dolichol carrier. In addition, dolichols can be adducted to proteins as a posttranslational modification, a process in which branched carbohydrate trees are forme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl Beta-D-glucosyl Phosphate
Dolichyl β--glucosyl phosphate is a molecule involved in glycosylation Glycosylation is the reaction in which a carbohydrate (or ' glycan'), i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor) in order to form a glycoconjugate. In biology (but not al .... It is a polyprenyl glycosyl phosphate having dolichol as the polyprenyl component and β--glucose as the glycosyl component. See also * Dolichylphosphate-glucose phosphodiesterase References Phospholipids {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-diphosphate—polyphosphate Phosphotransferase
In enzymology, a dolichyl-diphosphate-polyphosphate phosphotransferase () is an enzyme that catalyzes the chemical reaction :dolichyl diphosphate + (phosphate)n \rightleftharpoons dolichyl phosphate + (phosphate)n+1 Thus, the two substrates of this enzyme are dolichyl diphosphate and (phosphate)n, whereas its two products are dolichyl phosphate and (phosphate)n+1. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferase Phosphotransferases are a category of enzymes ( EC number 2.7) that catalyze phosphorylation reactions. The general form of the reactions they catalyze is: :A-P + B \rightleftharpoons B-P + A Where ''P'' is a phosphate group and A and B are the do ...s) with a phosphate group as acceptor. The systematic name of this enzyme class is dolichyl-diphosphate:polyphosphate phosphotransferase. This enzyme is also called dolichylpyrophosphate:polyphosphate phosphotransferase. References * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphatase
The enzyme dolichyl-phosphatase (EC 3.1.3.51) catalyzes the reaction :dolichyl phosphate + H2O \rightleftharpoons dolichol + phosphate This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... is dolichyl-phosphate phosphohydrolase. Other names in common use include dolichol phosphate phosphatase, dolichol phosphatase, dolichol monophosphatase, dolichyl monophosphate phosphatase, dolichyl phosphate phosphatase, polyisoprenyl phosphate phosphatase, polyprenylphosphate phosphatase, and Dol-''P'' phosphatase. This enzyme participates in ''N''-linked-glycan biosynthesis. References * * * EC 3.1.3 Enzymes of unknown structure {{3.1-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphate Alpha-N-acetylglucosaminyltransferase
In enzymology, a dolichyl-phosphate alpha-N-acetylglucosaminyltransferase () is an enzyme that catalyzes the chemical reaction :UDP-N-acetyl-D-glucosamine + dolichyl phosphate \rightleftharpoons UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and dolichyl phosphate Dolichol monophosphate is a fatty alcohol Fatty alcohols (or long-chain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4–6 carbons to as many as 22–26, derived from natural fat ..., whereas its two products are UDP and dolichyl N-acetyl-alpha-D-glucosaminyl phosphate. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase. Other names in common use include uridine diphosphoacetylglucosamine-doli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphate Beta-D-mannosyltransferase
In enzymology, a dolichyl-phosphate beta-D-mannosyltransferase () is an enzyme that catalyzes the chemical reaction :GDP-mannose + dolichyl phosphate \rightleftharpoons GDP + dolichyl D-mannosyl phosphate Thus, the two substrates of this enzyme are GDP-mannose and dolichyl phosphate, whereas its two products are GDP and dolichyl D-mannosyl phosphate. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase. Other names in common use include GDP-Man:DolP mannosyltransferase, dolichyl mannosyl phosphate synthase, dolichyl-phospho-mannose synthase, GDP-mannose:dolichyl-phosphate mannosyltran ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphate Beta-glucosyltransferase
In enzymology, a dolichyl-phosphate beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction :UDP-glucose + dolichyl phosphate \rightleftharpoons UDP + dolichyl beta-D-glucosyl phosphate Thus, the two substrates of this enzyme are UDP-glucose and dolichyl phosphate, whereas its two products are UDP and dolichyl beta-D-glucosyl phosphate. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase. Other names in common use include polyprenyl phosphate:UDP-D-glucose glucosyltransferase, UDP-glucose dolichyl-phosphate glucosyltransferase, uridine diphosphoglucose-dolichol glucosyltransferase, UDP-glucose:dolichol phosphate glucosyltransferase, UDP-glucose:dolicholphosphoryl glucosyltransferase, UDP-glucose:dolichyl monophosphate glucosyltransferase, and UDP-glucose:dolichyl phosphate glucosyltransferase. This enzyme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphate D-xylosyltransferase
In enzymology, a dolichyl-phosphate D-xylosyltransferase () is an enzyme that catalyzes the chemical reaction :UDP-D-xylose + dolichyl phosphate \rightleftharpoons UDP + dolichyl D-xylosyl phosphate Thus, the two substrates of this enzyme are UDP-D-xylose and dolichyl phosphate, whereas its two products are UDP and dolichyl D-xylosyl phosphate Dolichyl, related to Dolichol, is used in the names of: *Dolichyl beta-D-glucosyl phosphate, a molecule involved in glycosylation *Dolichyl-diphosphate—polyphosphate phosphotransferase (EC 2.7.4.20) * Dolichyl-diphosphooligosaccharide—protein .... This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase. References * EC 2.4.2 Enzymes of unknown structure {{2.4-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphate-mannose—glycolipid Alpha-mannosyltransferase
Dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase (, ''Man5GlcNAc2-PP-Dol mannosyltransferase'', '' ALG3'', ''dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase'', ''Not56-like protein'', ''Alg3 alpha-1,3-mannosyl transferase'', ''Dol-P-Man:Man5GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase'') is an enzyme with systematic name ''dolichyl beta-D-mannosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-mannosyltransferase''. This enzyme catalyses the following chemical reaction : dolichyl beta-D-mannosyl phosphate + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)- 6)">-Man-alpha-(1->6)D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol \rightleftharpoons D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)- 3)-D-Man-alpha-(1->6)">-Man-alpha-(1->3)-D-Man-alpha-(1->6)D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-phosphate-mannose-protein Mannosyltransferase
In enzymology, a dolichyl-phosphate-mannose-protein mannosyltransferase () is an enzyme that catalyzes the chemical reaction :dolichyl phosphate D-mannose + protein \rightleftharpoons dolichyl phosphate + O-D-mannosylprotein Thus, the two substrates of this enzyme are dolichyl phosphate D-mannose and protein, whereas its two products are dolichyl phosphate and O-D-mannosylprotein. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase. Other names in common use include dolichol phosphomannose-protein mannosyltransferase, and protein O-D-mannosyltransferase. A human gene that codes for this enzyme is POMT1 Protein O-mannosyl-transferase 1 is an enzyme that in humans is encoded by the ''POMT1'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichyl-xylosyl-phosphate—protein Xylosyltransferase
In enzymology, a dolichyl-xylosyl-phosphate-protein xylosyltransferase () is an enzyme that catalyzes the chemical reaction :dolichyl D-xylosyl phosphate + protein \rightleftharpoons dolichyl phosphate + D-xylosylprotein Thus, the two substrates of this enzyme are dolichyl D-xylosyl phosphate and protein, whereas its two products are dolichyl phosphate Dolichol monophosphate is a fatty alcohol Fatty alcohols (or long-chain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4–6 carbons to as many as 22–26, derived from natural fat ... and D-xylosylprotein. This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase. References * EC 2.4.2 Enzymes of unknown structure {{2.4-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |