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Dolichyl Diphosphate
Dolichyl, related to Dolichol, is used in the names of: * Dolichyl beta-D-glucosyl phosphate, a molecule involved in glycosylation *Dolichyl-diphosphate—polyphosphate phosphotransferase (EC 2.7.4.20) * Dolichyl-diphosphooligosaccharide—protein glycotransferase (EC 2.4.1.119) * Dolichyl-phosphatase (EC 3.1.3.51) * Dolichyl-phosphate alpha-N-acetylglucosaminyltransferase (EC 2.4.1.153) * Dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) * Dolichyl-phosphate beta-glucosyltransferase (EC 2.4.1.117) *Dolichyl-phosphate D-xylosyltransferase (EC 2.4.2.32) * Dolichyl-phosphate-mannose—glycolipid alpha-mannosyltransferase (EC 2.4.1.130) *Dolichyl-phosphate-mannose-protein mannosyltransferase (EC 2.4.1.109) * Dolichyl-xylosyl-phosphate—protein xylosyltransferase (EC 2.4.2.33) *UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase In enzymology, an UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase () is an enzyme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dolichol
Dolichol refers to any of a group of long-chain mostly unsaturated organic compounds that are made up of varying numbers of isoprene units terminating in an α-saturated isoprenoid group, containing an alcohol functional group. Functions Dolichols play a role in the co-translational modification of proteins known as ''N''-glycosylation in the form of dolichol phosphate. Dolichols function as a membrane anchor for the formation of the oligosaccharide Glc3-Man9-GlcNAc2 (where Glc is glucose, Man is mannose, and GlcNAc is ''N''-acetylglucosamine). This oligosaccharide is transferred from the dolichol donor onto certain asparagine residues (onto a specific sequence that is "Asn-X-Ser/Thr") of newly forming polypeptide chains. Dolichol is also involved in transfer of the monosaccharides to the forming Glc3-Man9-GlcNAc2-Dolichol carrier. In addition, dolichols can be adducted to proteins as a posttranslational modification, a process in which branched carbohydrate trees are forme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |