DdRNAi
DNA detailed study DNA-directed RNA interference (DRNAI) is a gene silencing, gene-silencing technique that utilizes DNA constructs to activate an animal cell's endogenous RNA interference (RNAI) pathways. DNA constructs are designed to express self-complementary Double-stranded RNA, double-stranded RNAs, typically Short hairpin RNA, short-hairpin RNAs , that bring about the silencing of a target gene or genes once processed. Any RNA, including endogenous messenger RNA (mRNAs) or viral RNAs, can be silenced by designing constructs to express double-stranded RNA complementary to the desired mRNA target. This mechanism has been demonstrated to work as a novel therapeutic to silence disease-causing genes across a range of disease models, including viral diseases such as HIV, hepatitis B or hepatitis C, or diseases associated with altered expression of endogenous genes such as drug-resistant non-small cell lung cancer, lung cancer, neuropathic pain, advanced cancer, and retinitis pig ...
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DdRNAi Constructs Jpg
DNA detailed study DNA-directed RNA interference (DRNAI) is a gene silencing, gene-silencing technique that utilizes DNA constructs to activate an animal cell's endogenous RNA interference (RNAI) pathways. DNA constructs are designed to express self-complementary Double-stranded RNA, double-stranded RNAs, typically Short hairpin RNA, short-hairpin RNAs , that bring about the silencing of a target gene or genes once processed. Any RNA, including endogenous messenger RNA (mRNAs) or viral RNAs, can be silenced by designing constructs to express double-stranded RNA complementary to the desired mRNA target. This mechanism has been demonstrated to work as a novel therapeutic to silence disease-causing genes across a range of disease models, including viral diseases such as HIV, hepatitis B or hepatitis C, or diseases associated with altered expression of endogenous genes such as drug-resistant non-small cell lung cancer, lung cancer, neuropathic pain, advanced cancer, and retinitis pig ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]